PMID- 37368025 OWN - NLM STAT- MEDLINE DCOM- 20230823 LR - 20230823 IS - 1432-5233 (Electronic) IS - 0940-5429 (Linking) VI - 60 IP - 10 DP - 2023 Oct TI - Convolutional neural network-based sea lion optimization algorithm for the detection and classification of diabetic retinopathy. PG - 1377-1389 LID - 10.1007/s00592-023-02122-y [doi] AB - AIMS: Diabetic retinopathy (DR) becomes a complicated type of diabetic that causes damage to the blood vessels of the retina's light-sensitive tissue. DR may initially cause mild symptoms or no symptoms. But prolonged DR results in permanent vision loss, and hence, it is necessary to detect the DR at an early stage. METHODS: Manual diagnosing of DR retina fundus image is a time-consuming process and sometimes leads to misdiagnosis. The existing DR detection model faces few shortcomings in case of improper detection accuracy, higher loss or error values, high feature dimensionality, not suitable for large datasets, high computational complexity, poor performances, unbalanced and limited number of data points, and so on. As a result, the DR is diagnosed in this paper through four critical phases to tackle the shortcomings. The retinal images are cropped during preprocessing to reduce unwanted noises and redundant data. The images are then segmented using a modified level set algorithm based on pixel characteristics. RESULTS: Here, an Aquila optimizer is employed in extracting the segmented image. Finally, for optimal classification of DR images, the study proposes a convolutional neural network-oriented sea lion optimization (CNN-SLO) algorithm. Here, the CNN-SLO algorithm classifies the retinal images into five classes (healthy, moderate, mild, proliferative and severe). CONCLUSION: The experimental investigation is performed for Kaggle datasets with respect to diverse evaluation measures to deliberate the performances of the proposed system. CI - (c) 2023. Springer-Verlag Italia S.r.l., part of Springer Nature. FAU - Hemanth, S V AU - Hemanth SV AUID- ORCID: 0000-0002-7829-6708 AD - Department of Computer Science and Engineering, Kalasalingam Academy of Research and Education (Deemed to be University), Srivilliputhur, Tamil Nadu, India. hemanth.svace@gmail.com. FAU - Alagarsamy, Saravanan AU - Alagarsamy S AD - Department of Computer Science and Engineering, Kalasalingam Academy of Research and Education (Deemed to be University), Srivilliputhur, Tamil Nadu, India. FAU - Dhiliphan Rajkumar, T AU - Dhiliphan Rajkumar T AD - Department of Computer Science and Engineering, Kalasalingam Academy of Research and Education (Deemed to be University), Srivilliputhur, Tamil Nadu, India. LA - eng PT - Journal Article DEP - 20230627 PL - Germany TA - Acta Diabetol JT - Acta diabetologica JID - 9200299 SB - IM MH - Animals MH - *Diabetic Retinopathy/diagnosis MH - *Sea Lions MH - Neural Networks, Computer MH - Algorithms MH - Retina/diagnostic imaging MH - *Diabetes Mellitus OTO - NOTNLM OT - Convolutional neural network and Kaggle datasets OT - Diabetic retinopathy OT - Modified level set OT - Sea lion optimization EDAT- 2023/06/27 13:10 MHDA- 2023/08/23 06:42 CRDT- 2023/06/27 11:06 PHST- 2022/10/06 00:00 [received] PHST- 2023/05/20 00:00 [accepted] PHST- 2023/08/23 06:42 [medline] PHST- 2023/06/27 13:10 [pubmed] PHST- 2023/06/27 11:06 [entrez] AID - 10.1007/s00592-023-02122-y [pii] AID - 10.1007/s00592-023-02122-y [doi] PST - ppublish SO - Acta Diabetol. 2023 Oct;60(10):1377-1389. doi: 10.1007/s00592-023-02122-y. Epub 2023 Jun 27.