PMID- 37372507
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230701
IS  - 2304-8158 (Print)
IS  - 2304-8158 (Electronic)
IS  - 2304-8158 (Linking)
VI  - 12
IP  - 12
DP  - 2023 Jun 7
TI  - Determination of Coenzyme Q10 Content in Food By-Products and Waste by 
      High-Performance Liquid Chromatography Coupled with Diode Array Detection.
LID - 10.3390/foods12122296 [doi]
LID - 2296
AB  - Coenzyme Q10 (CoQ10) is a vitamin-like compound found naturally in plant- and 
      animal-derived materials. This study aimed to determine the level of CoQ10 in 
      some food by-products (oil press cakes) and waste (fish meat and chicken hearts) 
      to recover this compound for further use as a dietary supplement. The analytical 
      method involved ultrasonic extraction using 2-propanol, followed by 
      high-performance liquid chromatography with diode array detection (HPLC-DAD). The 
      HPLC-DAD method was validated in terms of linearity and measuring range, limits 
      of detection (LOD) and quantification (LOQ), trueness, and precision. As a 
      result, the calibration curve of CoQ10 was linear over the concentration range of 
      1-200 microg/mL, with an LOD of 22 microg/mL and an LOQ of 0.65 microg/mL. The CoQ10 content 
      varied from not detected in the hempseed press cake and the fish meat to 84.80 
      microg/g in the pumpkin press cake and 383.25 microg/g in the lyophilized chicken hearts; 
      very good recovery rates and relative standard deviations (RSDs) were obtained 
      for the pumpkin press cake (100.9-116.0% with RSDs between 0.05-0.2%) and the 
      chicken hearts (99.3-106.9% CH with RSDs between 0.5-0.7%), showing the 
      analytical method's trueness and precision and thus its accuracy. In conclusion, 
      a simple and reliable method for determining CoQ10 levels has been developed 
      here.
FAU - Semeniuc, Cristina Anamaria
AU  - Semeniuc CA
AUID- ORCID: 0000-0002-9721-4560
AD  - Faculty of Food Science and Technology, University of Agricultural Sciences and 
      Veterinary Medicine of Cluj-Napoca, 3-5 Manastur St., 400372 Cluj-Napoca, 
      Romania.
FAU - Ranga, Floricuta
AU  - Ranga F
AD  - Faculty of Food Science and Technology, University of Agricultural Sciences and 
      Veterinary Medicine of Cluj-Napoca, 3-5 Manastur St., 400372 Cluj-Napoca, 
      Romania.
FAU - Podar, Andersina Simina
AU  - Podar AS
AUID- ORCID: 0000-0001-9665-3142
AD  - Centre for Technology Transfer-BioTech, 64 Calea Floresti, 400509 Cluj-Napoca, 
      Romania.
FAU - Ionescu, Simona Raluca
AU  - Ionescu SR
AD  - Faculty of Food Science and Technology, University of Agricultural Sciences and 
      Veterinary Medicine of Cluj-Napoca, 3-5 Manastur St., 400372 Cluj-Napoca, 
      Romania.
FAU - Socaciu, Maria-Ioana
AU  - Socaciu MI
AUID- ORCID: 0000-0002-8871-1995
AD  - Faculty of Food Science and Technology, University of Agricultural Sciences and 
      Veterinary Medicine of Cluj-Napoca, 3-5 Manastur St., 400372 Cluj-Napoca, 
      Romania.
FAU - Fogarasi, Melinda
AU  - Fogarasi M
AUID- ORCID: 0000-0002-9561-1183
AD  - Faculty of Food Science and Technology, University of Agricultural Sciences and 
      Veterinary Medicine of Cluj-Napoca, 3-5 Manastur St., 400372 Cluj-Napoca, 
      Romania.
FAU - Farcas, Anca Corina
AU  - Farcas AC
AUID- ORCID: 0000-0002-1392-4080
AD  - Faculty of Food Science and Technology, University of Agricultural Sciences and 
      Veterinary Medicine of Cluj-Napoca, 3-5 Manastur St., 400372 Cluj-Napoca, 
      Romania.
FAU - Vodnar, Dan Cristian
AU  - Vodnar DC
AUID- ORCID: 0000-0001-5407-8071
AD  - Faculty of Food Science and Technology, University of Agricultural Sciences and 
      Veterinary Medicine of Cluj-Napoca, 3-5 Manastur St., 400372 Cluj-Napoca, 
      Romania.
FAU - Socaci, Sonia Ancuta
AU  - Socaci SA
AUID- ORCID: 0000-0003-0594-4628
AD  - Faculty of Food Science and Technology, University of Agricultural Sciences and 
      Veterinary Medicine of Cluj-Napoca, 3-5 Manastur St., 400372 Cluj-Napoca, 
      Romania.
LA  - eng
GR  - PN-III-P4-ID-PCE-2020-1847/The Romanian Ministry of Education and Research, 
      CNCS-UEFISCDI, project number PN-III-P4-ID-PCE-2020-1847, within PNCDI III/
PT  - Journal Article
DEP - 20230607
PL  - Switzerland
TA  - Foods
JT  - Foods (Basel, Switzerland)
JID - 101670569
PMC - PMC10297063
OTO - NOTNLM
OT  - 2-propanol extracts
OT  - coenzyme Q10
OT  - diode-array detection
OT  - food by-products
OT  - food waste
OT  - high-performance liquid chromatography
OT  - ultrasonic extraction
COIS- The authors declare no conflict of interest.
EDAT- 2023/06/28 06:42
MHDA- 2023/06/28 06:43
PMCR- 2023/06/07
CRDT- 2023/06/28 01:13
PHST- 2023/05/06 00:00 [received]
PHST- 2023/06/05 00:00 [revised]
PHST- 2023/06/06 00:00 [accepted]
PHST- 2023/06/28 06:43 [medline]
PHST- 2023/06/28 06:42 [pubmed]
PHST- 2023/06/28 01:13 [entrez]
PHST- 2023/06/07 00:00 [pmc-release]
AID - foods12122296 [pii]
AID - foods-12-02296 [pii]
AID - 10.3390/foods12122296 [doi]
PST - epublish
SO  - Foods. 2023 Jun 7;12(12):2296. doi: 10.3390/foods12122296.