PMID- 37375234
OWN - NLM
STAT- MEDLINE
DCOM- 20230629
LR  - 20230701
IS  - 1420-3049 (Electronic)
IS  - 1420-3049 (Linking)
VI  - 28
IP  - 12
DP  - 2023 Jun 9
TI  - Green Biosynthesis of Zinc Oxide Nanoparticles Using Pluchea indica Leaf Extract: 
      Antimicrobial and Photocatalytic Activities.
LID - 10.3390/molecules28124679 [doi]
LID - 4679
AB  - Nanotechnology is playing a critical role in several essential technologies with 
      nanoscale structures (nanoparticles) in areas of the environment and biomedicine. 
      In this work, the leaf extract of Pluchea indica was utilized to biosynthesize 
      zinc oxide nanoparticles (ZnONPs) for the first time and evaluated for 
      antimicrobial and photocatalytic activities. Different experimental methods were 
      used to characterize the biosynthesized ZnONPs. The biosynthesized ZnONPs showed 
      maximum Ultraviolet-visible spectroscopy (UV-vis) absorbance at a wavelength of 
      360 nm. The X-Ray diffraction (XRD) pattern of the ZnONPs exhibits seven strong 
      reflection peaks, and the average particle size was 21.9 nm. Fourier-transform 
      infrared spectroscopy (FT-IR) spectrum analysis reveals the presence of 
      functional groups that help in biofabrication. The existence of Zn and O was 
      confirmed by the Energy-dispersive X-ray (EDX) spectrum and the morphology by SEM 
      images. Antimicrobial studies showed that the biosynthesized ZnONPs have 
      antimicrobial efficacy against Escherichia coli, Pseudomonas aeruginosa, 
      Enterococcus faecalis, Bacillus subtilis, Staphylococcus aureus, Candida albicans 
      and Cryptococcus neoformans where inhibition zones at concentration 1000 microg/mL 
      were 21.83 +/- 0.76, 13.0 +/- 1.1, 14.9 +/- 0.85, 24.26 +/- 1.1, 17.0 +/- 1.0, 20.67 +/- 0.57 
      and 19.0 +/- 1.0 mm respectively. Under both dark and sunlight irradiation, the 
      photocatalytic activity of ZnONPs was evaluated towards the degradation of the 
      thiazine dye (methylene blue-MB). Approximately 95% of the MB dye was broken down 
      at pH 8 after 150 min of sunlight exposure. The aforementioned results, 
      therefore, suggest that ZnONPs synthesized by implementing environmentally 
      friendly techniques can be employed for a variety of environmental and biomedical 
      applications.
FAU - Al-Askar, Abdulaziz A
AU  - Al-Askar AA
AD  - Department of Botany and Microbiology, Faculty of Science, King Saud University, 
      P.O. Box 2455, Riyadh 11451, Saudi Arabia.
FAU - Hashem, Amr H
AU  - Hashem AH
AUID- ORCID: 0000-0002-0024-3606
AD  - Botany and Microbiology Department, Faculty of Science, Al-Azhar University, 
      Cairo 11884, Egypt.
FAU - Elhussieny, Nadeem I
AU  - Elhussieny NI
AD  - Department of Life Science and Chemistry, Constructor University, 28759 Bremen, 
      Germany.
AD  - Institute of Environmental Biology and Biotechnology, University of Applied 
      Sciences Bremen, Am Neustadtwall 30, 28199 Bremen, Germany.
FAU - Saied, Ebrahim
AU  - Saied E
AUID- ORCID: 0000-0002-5622-7912
AD  - Botany and Microbiology Department, Faculty of Science, Al-Azhar University, 
      Cairo 11884, Egypt.
LA  - eng
GR  - RSP2023R505/King Saud University/
PT  - Journal Article
DEP - 20230609
PL  - Switzerland
TA  - Molecules
JT  - Molecules (Basel, Switzerland)
JID - 100964009
RN  - 0 (Anti-Bacterial Agents)
RN  - SOI2LOH54Z (Zinc Oxide)
RN  - 0 (Plant Extracts)
RN  - 0 (Anti-Infective Agents)
SB  - IM
MH  - Anti-Bacterial Agents/pharmacology/chemistry
MH  - *Zinc Oxide/pharmacology/chemistry
MH  - Spectroscopy, Fourier Transform Infrared
MH  - *Metal Nanoparticles/chemistry
MH  - Plant Extracts/pharmacology/chemistry
MH  - *Anti-Infective Agents/pharmacology
MH  - Escherichia coli
MH  - Microbial Sensitivity Tests
MH  - X-Ray Diffraction
PMC - PMC10304739
OTO - NOTNLM
OT  - antimicrobial activity
OT  - green biosynthesis
OT  - photocatalytic activity
OT  - zinc oxide nanoparticles
COIS- The authors declare no conflict of interest.
EDAT- 2023/06/28 06:42
MHDA- 2023/06/29 06:43
PMCR- 2023/06/09
CRDT- 2023/06/28 01:31
PHST- 2023/05/18 00:00 [received]
PHST- 2023/05/31 00:00 [revised]
PHST- 2023/06/05 00:00 [accepted]
PHST- 2023/06/29 06:43 [medline]
PHST- 2023/06/28 06:42 [pubmed]
PHST- 2023/06/28 01:31 [entrez]
PHST- 2023/06/09 00:00 [pmc-release]
AID - molecules28124679 [pii]
AID - molecules-28-04679 [pii]
AID - 10.3390/molecules28124679 [doi]
PST - epublish
SO  - Molecules. 2023 Jun 9;28(12):4679. doi: 10.3390/molecules28124679.