PMID- 37379816
OWN - NLM
STAT- MEDLINE
DCOM- 20230728
LR  - 20240412
IS  - 1423-0356 (Electronic)
IS  - 0025-7931 (Linking)
VI  - 102
IP  - 7
DP  - 2023
TI  - Effect of Pulmonary Rehabilitation on COPD Assessment Test Items in Individuals 
      Classified as GOLD Group E.
PG  - 469-478
LID - 10.1159/000531011 [doi]
AB  - BACKGROUND: A new Global Initiative for Chronic Obstructive Lung Disease (GOLD) 
      classification has been proposed, based also on COPD Assessment Test (CAT). 
      OBJECTIVES: The aim of this large, multicenter, retrospective study was to 
      determine the impact of pulmonary rehabilitation (PR) on CAT items in individuals 
      with COPD, GOLD group E, recovering from an exacerbation (ECOPD). As secondary 
      aims, we evaluated whether gender, associated chronic respiratory failure (CRF), 
      and age might influence results. METHODS: Data of 2,213 individuals with 
      available paired pre- and post-PR CAT were analyzed. Other common outcome 
      measures were also assessed. RESULTS: After PR, total CAT improved from 20.8 +/- 
      7.8 to 12.4 +/- 6.9 (p = 0.000), and 1,911 individuals (86.4%) reached the minimal 
      clinically important difference (MCID). All CAT items improved significantly 
      without any significant difference among them. However, item "confidence with 
      disease" improved significantly more in males than in females (p = 0.009). Total 
      CAT and six out of eight items improved significantly more in individuals with 
      CRF than in those without (all p < 0.001). Total CAT and three items improved 
      significantly more in younger than in older individuals (p = 0.023). Only 
      presence of CRF was significantly associated with the probability of improving 
      total CAT more than the MCID. CONCLUSION: In individuals with COPD, GOLD group E, 
      recovering from ECOPD, PR improves all CAT items; however, gender, associated CRF 
      and age may influence the effect size, suggesting the need to evaluate all items 
      in addition to total CAT score.
CI  - (c) 2023 S. Karger AG, Basel.
FAU - Vitacca, Michele
AU  - Vitacca M
AD  - Respiratory Rehabilitation of the Institute of Lumezzane, Istituti Clinici 
      Scientifici Maugeri IRCCS, Brescia, Italy.
FAU - Paneroni, Mara
AU  - Paneroni M
AD  - Respiratory Rehabilitation of the Institute of Lumezzane, Istituti Clinici 
      Scientifici Maugeri IRCCS, Brescia, Italy.
FAU - Spanevello, Antonio
AU  - Spanevello A
AD  - Respiratory Rehabilitation of the Institute of Tradate, Istituti Clinici 
      Scientifici Maugeri IRCCS, Varese, Italy.
AD  - Department of Medicine and Surgery, University of Insubria, Varese, Italy.
FAU - Maniscalco, Mauro
AU  - Maniscalco M
AD  - Respiratory Rehabilitation of the Institute of Telese, Istituti Clinici 
      Scientifici Maugeri IRCCS, Benevento, Italy.
FAU - Diasparra, Aldo
AU  - Diasparra A
AD  - Respiratory Rehabilitation of the Institute of Ginosa, Istituti Clinici 
      Scientifici Maugeri, Taranto, Italy.
FAU - Aliani, Maria
AU  - Aliani M
AD  - Respiratory Rehabilitation of the Institute of Bari, Istituti Clinici Scientifici 
      Maugeri IRCCS, Bari, Italy.
FAU - Ambrosino, Nicolino
AU  - Ambrosino N
AD  - Respiratory Rehabilitation of the Institute of Montescano, Istituti Clinici 
      Scientifici Maugeri IRCCS, Pavia, Italy.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20230628
PL  - Switzerland
TA  - Respiration
JT  - Respiration; international review of thoracic diseases
JID - 0137356
RN  - Pulmonary Disease, Chronic Obstructive, Severe Early-Onset
SB  - IM
MH  - Male
MH  - Female
MH  - Humans
MH  - Retrospective Studies
MH  - *Pulmonary Disease, Chronic Obstructive
MH  - *Asthma/complications
MH  - Outcome Assessment, Health Care
MH  - Quality of Life
MH  - Surveys and Questionnaires
MH  - Dyspnea/rehabilitation
OTO - NOTNLM
OT  - Dyspnea
OT  - Exacerbation
OT  - Exercise capacity
OT  - Exercise training
OT  - Health status
EDAT- 2023/06/29 01:08
MHDA- 2023/07/28 06:43
CRDT- 2023/06/28 18:23
PHST- 2023/03/01 00:00 [received]
PHST- 2023/04/11 00:00 [accepted]
PHST- 2023/07/28 06:43 [medline]
PHST- 2023/06/29 01:08 [pubmed]
PHST- 2023/06/28 18:23 [entrez]
AID - 000531011 [pii]
AID - 10.1159/000531011 [doi]
PST - ppublish
SO  - Respiration. 2023;102(7):469-478. doi: 10.1159/000531011. Epub 2023 Jun 28.