PMID- 37382484
OWN - NLM
STAT- Publisher
LR  - 20230801
IS  - 1530-8898 (Electronic)
IS  - 0898-929X (Linking)
VI  - 35
IP  - 9
DP  - 2023 Sep 1
TI  - Corticostriatal Connectivity during Prosocial Decision-making Relates to Giving 
      Behavior during Adolescence.
PG  - 1432-1445
LID - 10.1162/jocn_a_02024 [doi]
AB  - Prosocial behavior during adolescence becomes more differentiated based on the 
      recipient of the action as well as the perceived value or benefit, relative to 
      the cost to self, for the recipients. The current study investigated how 
      functional connectivity of corticostriatal networks tracked the value of 
      prosocial decisions as a function of target recipient (caregiver, friend, 
      stranger) and age of the giver, and how they related to giving behavior. Two 
      hundred sixty-one adolescents (9-15 and 19-20 years of age) completed a 
      decision-making task in which they could give money to caregivers, friends, and 
      strangers while undergoing fMRI. Results indicated that adolescents were more 
      likely to give to others as the value of the prosocial decision (i.e., the 
      difference between the benefit to other relative to the cost to self) increased; 
      this effect was stronger for known (caregiver and friends) than unknown targets, 
      and increased with age. Functional connectivity between the nucleus accumbens 
      (NAcc) and OFC increased as the value of the prosocial decisions decreased for 
      strangers, but not for known others, irrespective of choice. This differentiated 
      NAcc-OFC functional connectivity during decision-making as a function of value 
      and target also increased with age. Furthermore, regardless of age, individuals 
      who evinced greater value-related NAcc-OFC functional connectivity when 
      considering giving to strangers relative to known others showed smaller 
      differentiated rates of giving between targets. These findings highlight the role 
      of corticostriatal development in supporting the increasing complexity of 
      prosocial development across adolescence.
CI  - (c) 2023 Massachusetts Institute of Technology. Published under a Creative Commons 
      Attribution 4.0 International (CC BY 4.0) license.
FAU - Uy, Jessica P
AU  - Uy JP
AUID- ORCID: 0000-0001-7316-3562
AD  - University of California, Los Angeles.
FAU - Fuligni, Andrew J
AU  - Fuligni AJ
AD  - University of California, Los Angeles.
FAU - Eisenberger, Naomi I
AU  - Eisenberger NI
AD  - University of California, Los Angeles.
FAU - Crone, Eveline A
AU  - Crone EA
AD  - Erasmus University Rotterdam, The Netherlands.
FAU - Telzer, Eva H
AU  - Telzer EH
AD  - University of North Carolina, Chapel Hill.
FAU - Galvan, Adriana
AU  - Galvan A
AD  - University of California, Los Angeles.
LA  - eng
GR  - BSC 1551952/Division of Social and Economic Sciences/
GR  - R01HD093823-01/Eunice Kennedy Shriver National Institute of Child Health and 
      Human Development/
PT  - Journal Article
PL  - United States
TA  - J Cogn Neurosci
JT  - Journal of cognitive neuroscience
JID - 8910747
SB  - IM
EDAT- 2023/06/29 13:42
MHDA- 2023/06/29 13:42
CRDT- 2023/06/29 09:33
PHST- 2023/06/29 13:42 [pubmed]
PHST- 2023/06/29 13:42 [medline]
PHST- 2023/06/29 09:33 [entrez]
AID - 116596 [pii]
AID - 10.1162/jocn_a_02024 [doi]
PST - ppublish
SO  - J Cogn Neurosci. 2023 Sep 1;35(9):1432-1445. doi: 10.1162/jocn_a_02024.