PMID- 37385550
OWN - NLM
STAT- Publisher
LR  - 20231020
IS  - 1097-6779 (Electronic)
IS  - 0016-5107 (Linking)
VI  - 98
IP  - 5
DP  - 2023 Nov
TI  - EUS-guided treatment of bleeding peristomal varices (with video).
PG  - 843-847
LID - S0016-5107(23)02676-7 [pii]
LID - 10.1016/j.gie.2023.06.026 [doi]
AB  - BACKGROUND AND AIMS: The use of EUS for peristomal varices (PV) is limited to 
      case reports. METHODS: Patients who underwent EUS-guided treatment of PV with 
      cyanoacrylate (CYA) and/or coils between April 2013 and December 2019 were 
      identified. All patients had failed previous therapies or had comorbidities 
      precluding other options. Endoscopic technique, adverse events (AEs), recurrent 
      bleeding, and repeat interventions were assessed. RESULTS: Twenty patients (12 
      men; median age, 62 years [interquartile range IQR, 54.8-69.5]) underwent 
      initial EUS-guided PV injection of CYA for secondary (n = 19) or primary (n = 1) 
      prophylaxis. Within 30 days, AEs occurred in 11 patients (55%), of which 8 were 
      mild. During a median 2.5 months (IQR, 2-8.5) of follow-up, confirmed (n = 6) or 
      suspected (n = 2) PV bleeding recurred; 5 of 8 recurrences were retreated with 
      CYA and/or coils without AEs. After retreatment, PV bleeding recurred in 2 
      patients a median of 6 months (IQR, 6-30) later. CONCLUSIONS: EUS appears to be a 
      safe and promising technique for treatment of PV.
CI  - Copyright (c) 2023 American Society for Gastrointestinal Endoscopy. Published by 
      Elsevier Inc. All rights reserved.
FAU - Sarkis, Yara
AU  - Sarkis Y
AD  - Department of Gastroenterology and Hepatology, Indiana University Health Medical 
      Center, Indianapolis, Indiana, USA.
FAU - Masuoka, Howard
AU  - Masuoka H
AD  - Department of Gastroenterology and Hepatology, Indiana University Health Medical 
      Center, Indianapolis, Indiana, USA.
FAU - Ghabril, Marwan
AU  - Ghabril M
AD  - Department of Gastroenterology and Hepatology, Indiana University Health Medical 
      Center, Indianapolis, Indiana, USA.
FAU - Gutta, Aditya
AU  - Gutta A
AD  - Department of Gastroenterology and Hepatology, Indiana University Health Medical 
      Center, Indianapolis, Indiana, USA.
FAU - Al-Haddad, Mohammad A
AU  - Al-Haddad MA
AD  - Department of Gastroenterology and Hepatology, Indiana University Health Medical 
      Center, Indianapolis, Indiana, USA.
FAU - DeWitt, John M
AU  - DeWitt JM
AD  - Department of Gastroenterology and Hepatology, Indiana University Health Medical 
      Center, Indianapolis, Indiana, USA.
LA  - eng
PT  - Journal Article
DEP - 20230628
PL  - United States
TA  - Gastrointest Endosc
JT  - Gastrointestinal endoscopy
JID - 0010505
SB  - IM
COIS- Disclosure The following author disclosed financial relationships: M. A. 
      Al-Haddad: Consultant for Interpace Diagnostics; research support from Amplified 
      Sciences and Creatics. All other authors disclosed no financial relationships.
EDAT- 2023/06/30 01:06
MHDA- 2023/06/30 01:06
CRDT- 2023/06/29 19:17
PHST- 2023/03/12 00:00 [received]
PHST- 2023/05/15 00:00 [revised]
PHST- 2023/06/20 00:00 [accepted]
PHST- 2023/06/30 01:06 [pubmed]
PHST- 2023/06/30 01:06 [medline]
PHST- 2023/06/29 19:17 [entrez]
AID - S0016-5107(23)02676-7 [pii]
AID - 10.1016/j.gie.2023.06.026 [doi]
PST - ppublish
SO  - Gastrointest Endosc. 2023 Nov;98(5):843-847. doi: 10.1016/j.gie.2023.06.026. Epub 
      2023 Jun 28.