PMID- 37388806
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230703
IS  - 2307-8960 (Print)
IS  - 2307-8960 (Electronic)
IS  - 2307-8960 (Linking)
VI  - 11
IP  - 17
DP  - 2023 Jun 16
TI  - Cardiac arrest secondary to pulmonary embolism treated with extracorporeal 
      cardiopulmonary resuscitation: Six case reports.
PG  - 4098-4104
LID - 10.12998/wjcc.v11.i17.4098 [doi]
AB  - BACKGROUND: Massive pulmonary embolism (PE) results in extremely high mortality 
      rates. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) can provide 
      circulatory and oxygenation support and rescue patients with massive PE. However, 
      there are relatively few studies of extracorporeal cardiopulmonary resuscitation 
      (ECPR) in patients with cardiac arrest (CA) secondary to PE. The aim of the 
      present study is to investigate the clinical use of ECPR in conjunction with 
      heparin anticoagulation in patients with CA secondary to PE. CASE SUMMARY: We 
      report the cases of six patients with CA secondary to PE treated with ECPR in the 
      intensive care unit of our hospital between June 2020 and June 2022. All six 
      patients experienced witnessed CA whilst in hospital. They had acute onset of 
      severe respiratory distress, hypoxia, and shock rapidly followed by CA and were 
      immediately given cardiopulmonary resuscitation and adjunctive VA-ECMO therapy. 
      During hospitalization, pulmonary artery computed tomography angiography was 
      performed to confirm the diagnosis of PE. Through anticoagulation management, 
      mechanical ventilation, fluid management, and antibiotic treatment, five patients 
      were successfully weaned from ECMO (83.33%), four patients survived for 30 d 
      after discharge (66.67%), and two patients had good neurological outcomes 
      (33.33%). CONCLUSION: For patients with CA secondary to massive PE, ECPR in 
      conjunction with heparin anticoagulation may improve outcomes.
CI  - (c)The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights 
      reserved.
FAU - Qiu, Min-Shan
AU  - Qiu MS
AD  - Department of Critical Care Medicine, Dongguan People's Hospital, Dongguan 
      523058, Guangdong Province, China.
FAU - Deng, Yong-Jin
AU  - Deng YJ
AD  - Department of Critical Care Medicine, Dongguan People's Hospital, Dongguan 
      523058, Guangdong Province, China.
FAU - Yang, Xue
AU  - Yang X
AD  - Department of Critical Care Medicine, Dongguan People's Hospital, Dongguan 
      523058, Guangdong Province, China.
FAU - Shao, Han-Quan
AU  - Shao HQ
AD  - Department of Critical Care Medicine, Dongguan People's Hospital, Dongguan 
      523058, Guangdong Province, China. hqshao0559@163.com.
LA  - eng
PT  - Case Reports
PL  - United States
TA  - World J Clin Cases
JT  - World journal of clinical cases
JID - 101618806
PMC - PMC10303601
OTO - NOTNLM
OT  - Cardiac arrest
OT  - Case report
OT  - Extracorporeal cardiopulmonary resuscitation
OT  - Outcomes
OT  - Pulmonary embolism
OT  - Shock
COIS- Conflict-of-interest statement: All the authors report no relevant conflicts of 
      interest for this article.
EDAT- 2023/06/30 13:11
MHDA- 2023/06/30 13:12
PMCR- 2023/06/16
CRDT- 2023/06/30 10:08
PHST- 2023/03/10 00:00 [received]
PHST- 2023/04/30 00:00 [revised]
PHST- 2023/05/22 00:00 [accepted]
PHST- 2023/06/30 13:12 [medline]
PHST- 2023/06/30 13:11 [pubmed]
PHST- 2023/06/30 10:08 [entrez]
PHST- 2023/06/16 00:00 [pmc-release]
AID - 10.12998/wjcc.v11.i17.4098 [doi]
PST - ppublish
SO  - World J Clin Cases. 2023 Jun 16;11(17):4098-4104. doi: 
      10.12998/wjcc.v11.i17.4098.