PMID- 37392471
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230724
IS  - 1944-8252 (Electronic)
IS  - 1944-8244 (Print)
IS  - 1944-8244 (Linking)
VI  - 15
IP  - 28
DP  - 2023 Jul 19
TI  - Dopamine-Based Copolymer Bottlebrushes for Functional Adhesives: Synthesis, 
      Characterization, and Applications in Surface Engineering of Antifouling 
      Polyethylene.
PG  - 34023-34030
LID - 10.1021/acsami.3c05124 [doi]
AB  - Nonpolar materials like polyolefins are notoriously challenging substrates for 
      surface modification. However, this challenge is not observed in nature. Barnacle 
      shells and mussels, for example, utilize catechol-based chemistry to fasten 
      themselves onto all kinds of materials, such as boat hulls or plastic waste. 
      Here, a design is proposed, synthesized, and demonstrated for a class of 
      catechol-containing copolymers (terpolymers) for surface functionalization of 
      polyolefins. Dopamine methacrylamide (DOMA), a catechol-containing monomer, is 
      incorporated into a polymer chain together with methyl methacrylate (MMA) and 
      2-(2-bromoisobutyryloxy)ethyl methacrylate (BIEM). DOMA serves as adhesion 
      points, BIEM provides functional sites for subsequent "grafting from" reactions, 
      and MMA provides the possibility for concentration and conformation adjustment. 
      First, the adhesive capabilities of DOMA are demonstrated by varying its content 
      in the copolymer. Then, terpolymers are spin-coated on model Si substrates. 
      Subsequently, the atom transfer initiator (ATRP) initiating group is used to 
      graft a poly(methyl methacrylate) (PMMA) layer from the copolymers, with 40% DOMA 
      content providing a coherent PMMA film. To demonstrate functionalization on a 
      polyolefin substrate, the copolymer is spin-coated on high-density polyethylene 
      (HDPE) substrates. A POEGMA layer is grafted from the ATRP initiator sites on the 
      terpolymer chain on the HDPE films to provide antifouling characteristics. Static 
      contact angle values and Fourier transform infrared (FTIR) spectra confirm the 
      presence of POEGMA on the HDPE substrate. Finally, the anticipated antifouling 
      functionality of grafted POEGMA is demonstrated by observing the inhibition of 
      nonspecific adsorption of the fluorescein-modified bovine serum albumin (BSA) 
      protein. The poly(oligoethylene glycol methacrylate) POEGMA layers grafted on 30% 
      DOMA-containing copolymers on HDPE show optimal antifouling performance 
      exhibiting a 95% reduction of BSA fluorescence compared to nonfunctionalized and 
      surface-fouled polyethylene. These results demonstrate the successful utilization 
      of catechol-based materials for functionalizing polyolefin surfaces.
FAU - Milatz, Roland
AU  - Milatz R
AUID- ORCID: 0000-0003-1755-5590
AD  - Department of Materials Science and Technology of Polymers, and Department of 
      Sustainable Polymer Chemistry, University of Twente, Enschede 7522 NB, The 
      Netherlands.
AD  - DPI, P.O. Box 902, 5600 AX Eindhoven, The Netherlands.
FAU - Duvigneau, Joost
AU  - Duvigneau J
AUID- ORCID: 0000-0002-2810-2768
AD  - Department of Materials Science and Technology of Polymers, and Department of 
      Sustainable Polymer Chemistry, University of Twente, Enschede 7522 NB, The 
      Netherlands.
FAU - Vancso, Gyula Julius
AU  - Vancso GJ
AUID- ORCID: 0000-0003-4718-0507
AD  - Department of Materials Science and Technology of Polymers, and Department of 
      Sustainable Polymer Chemistry, University of Twente, Enschede 7522 NB, The 
      Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20230701
PL  - United States
TA  - ACS Appl Mater Interfaces
JT  - ACS applied materials & interfaces
JID - 101504991
SB  - IM
PMC - PMC10360033
OTO - NOTNLM
OT  - antifouling
OT  - biomimetic adhesion
OT  - polydopamine
OT  - polyethylene grafting
OT  - surface functionalization
COIS- The authors declare no competing financial interest.
EDAT- 2023/07/01 21:09
MHDA- 2023/07/01 21:10
PMCR- 2023/07/21
CRDT- 2023/07/01 16:42
PHST- 2023/07/01 21:10 [medline]
PHST- 2023/07/01 21:09 [pubmed]
PHST- 2023/07/01 16:42 [entrez]
PHST- 2023/07/21 00:00 [pmc-release]
AID - 10.1021/acsami.3c05124 [doi]
PST - ppublish
SO  - ACS Appl Mater Interfaces. 2023 Jul 19;15(28):34023-34030. doi: 
      10.1021/acsami.3c05124. Epub 2023 Jul 1.