PMID- 37394447
OWN - NLM
STAT- MEDLINE
DCOM- 20230704
LR  - 20230705
IS  - 1472-6823 (Electronic)
IS  - 1472-6823 (Linking)
VI  - 23
IP  - 1
DP  - 2023 Jul 3
TI  - Insulinaemic potential of diet and lifestyle and risk of type 2 diabetes in the 
      Iranian adults: result from Yazd health study.
PG  - 136
LID - 10.1186/s12902-023-01364-9 [doi]
LID - 136
AB  - BACKGROUND: Previous studies have shown that insulin directly affects the risk of 
      type 2 diabetes mellitus (T2DM) but the relationship between insulinaemic 
      potential of diet and lifestyle and the T2DM risk is still unknown. Accordingly, 
      we aimed to investigate the relationship between the insulinaemic potential of 
      diet and lifestyle based on indices including empirical dietary index for 
      hyperinsulinaemia (EDIH), empirical lifestyle index for hyperinsulinaemia (ELIH), 
      empirical dietary index for insulin resistance (EDIR) and empirical lifestyle 
      index for insulin resistance (ELIR) and the T2DM risk in the Iranian adults. 
      METHODS: This study was performed on data of enrollment phase of the Yazd Health 
      Study (YaHS) and TAghzieh Mardom-e-Yazd (Yazd Nutrition Study) (TaMYZ) on 5714 
      adults aged 20-70 years (mean: 36.29 years). A validated food frequency 
      questionnaire and clinical tests were used to assess food intake and T2DM 
      ascertainment, respectively. We used the Cox regression analysis for determining 
      the relationship between the indices and T2DM risk. RESULTS: After adjusting for 
      confounding variables, our findings showed that diet with higher ELIH score is 
      2.28 times more likely for T2DM risk (RR 2.28 [95% CI 1.69-2.56]), but there was 
      no significant relationship between the EDIH, ELIR and EDIR scores and T2DM risk 
      in adults, in the entire study population. CONCLUSIONS: Our findings suggest that 
      diets with higher ELIH score increases the T2DM risk, but there was no 
      significant relationship between the EDIH, ELIR and EDIR scores and T2DM risk. 
      Further epidemiological studies are needed to confirm our findings.
CI  - (c) 2023. The Author(s).
FAU - Omrani, Morteza
AU  - Omrani M
AD  - Department of Nutrition, School of Public Health, Iran University of Medical 
      Sciences, Tehran, Iran.
FAU - Hosseinzadeh, Mahdieh
AU  - Hosseinzadeh M
AD  - Nutrition and Food Security Research Center, School of Public Health, Shahid 
      Sadoughi University of Medical Sciences, Yazd, Iran.
AD  - Department of Nutrition, School of Public Health, Shahid Sadoughi University of 
      Medical Sciences, Yazd, Iran.
FAU - Shab Bidar, Sakineh
AU  - Shab Bidar S
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences, Tehran, Iran.
FAU - Mirzaei, Masoud
AU  - Mirzaei M
AD  - Yazd Cardiovascular Research Center, Yazd Non-communicable Disease Research 
      Centre, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
FAU - Teymoori, Farshad
AU  - Teymoori F
AD  - Department of Nutrition, School of Public Health, Iran University of Medical 
      Sciences, Tehran, Iran.
AD  - Nutrition and Endocrine Research Center, Shahid Beheshti University of Medical 
      Sciences, Tehran, Iran.
FAU - Nadjarzadeh, Azadeh
AU  - Nadjarzadeh A
AD  - Nutrition and Food Security Research Center, School of Public Health, Shahid 
      Sadoughi University of Medical Sciences, Yazd, Iran.
FAU - Firouzabadi, Fatemeh Dehghani
AU  - Firouzabadi FD
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences, Tehran, Iran.
FAU - Rahideh, Seyedeh Tayebeh
AU  - Rahideh ST
AD  - Department of Nutrition, School of Public Health, Iran University of Medical 
      Sciences, Tehran, Iran. rahide.t@iums.ac.ir.
LA  - eng
PT  - Journal Article
DEP - 20230703
PL  - England
TA  - BMC Endocr Disord
JT  - BMC endocrine disorders
JID - 101088676
RN  - 0 (Insulin)
SB  - IM
MH  - Humans
MH  - Adult
MH  - *Diabetes Mellitus, Type 2/epidemiology/etiology
MH  - Iran/epidemiology
MH  - *Insulin Resistance
MH  - Diet/adverse effects
MH  - Insulin
MH  - Risk Factors
PMC - PMC10316619
OTO - NOTNLM
OT  - Empirical dietary index for hyperinsulinaemia
OT  - Empirical dietary index for insulin resistance
OT  - Empirical dietary indices for lifestyle
OT  - Empirical lifestyle index for insulin resistance
OT  - Type 2 diabetes
COIS- The authors declare that they have no conflict of interest.
EDAT- 2023/07/03 00:41
MHDA- 2023/07/04 06:42
PMCR- 2023/07/03
CRDT- 2023/07/02 23:31
PHST- 2022/11/07 00:00 [received]
PHST- 2023/05/09 00:00 [accepted]
PHST- 2023/07/04 06:42 [medline]
PHST- 2023/07/03 00:41 [pubmed]
PHST- 2023/07/02 23:31 [entrez]
PHST- 2023/07/03 00:00 [pmc-release]
AID - 10.1186/s12902-023-01364-9 [pii]
AID - 1364 [pii]
AID - 10.1186/s12902-023-01364-9 [doi]
PST - epublish
SO  - BMC Endocr Disord. 2023 Jul 3;23(1):136. doi: 10.1186/s12902-023-01364-9.