PMID- 37397143 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230704 IS - 2296-2360 (Print) IS - 2296-2360 (Electronic) IS - 2296-2360 (Linking) VI - 11 DP - 2023 TI - Echocardiographic parameters predicting spontaneous closure of ductus arteriosus in preterm infants. PG - 1198936 LID - 10.3389/fped.2023.1198936 [doi] LID - 1198936 AB - OBJECTIVE: To evaluate the value of echocardiographic parameters in predicting early spontaneous closure of ductus arteriosus in premature infants. METHODS: 222 premature infants admitted to the neonatal ward of our hospital were selected, and patent ductus arteriosus was detected by echocardiography 48 h after birth. On the 7th day, whether the ductus arteriosus was closed naturally in this cohort was observed. The infants whose ductus arteriosus were not closed were identified as the PDA group (n = 109), and the other infants were included in the control group (n = 113). The echocardiographic parameters of the two groups of premature infants at 48 h after birth were single-factor statistically and Pearson correlation analyzed, and the parameters with statistically significant differences in single-factor analyzed were selected for multivariate logistic stepwise regression analysis. RESULTS: The ductus arteriosus shunt velocity and the pressure difference between the descending aorta and the pulmonary artery (DeltaPs) in the PDA group were lower than those in the control group (P < 0.05). The pulmonary artery pressure (PASP) in the PDA group was higher than that in the control group (P < 0.05). According to the multivariate logistic stepwise regression analysis, only the maximum shunt velocity of ductus arteriosus was correlated with early spontaneous closure of ductus arteriosus in 48 h first echocardiographic parameters (P = 0.049). The receiver operating characteristic (ROC) curve indicates the optimal critical point of echocardiographic ductus arteriosus shunt velocity in premature infants 48 h after birth was 1.165 m/s. CONCLUSION: Echocardiographic parameters are of great value in predicting the early spontaneous closure of ductus arteriosus in premature infants. In particular, the ductus arteriosus shunt velocity is correlated with the early spontaneous closure of ductus arteriosus. CI - (c) 2023 He, Yang, Gan, Tang, Ran and Zhang. FAU - He, Minyu AU - He M AD - Department of Ultrasound, Chongqing Health Center for Women and Children, Chongqing, China. AD - Department of Ultrasound, Women and Children's Hospital of Chongqing Medical University, Chongqing, China. FAU - Yang, Zhengchun AU - Yang Z AD - Department of Ultrasound, Chongqing Health Center for Women and Children, Chongqing, China. AD - Department of Ultrasound, Women and Children's Hospital of Chongqing Medical University, Chongqing, China. FAU - Gan, Tian AU - Gan T AD - Department of Ultrasound, Chongqing Health Center for Women and Children, Chongqing, China. AD - Department of Ultrasound, Women and Children's Hospital of Chongqing Medical University, Chongqing, China. FAU - Tang, Jing AU - Tang J AD - Department of Ultrasound, Chongqing Health Center for Women and Children, Chongqing, China. AD - Department of Ultrasound, Women and Children's Hospital of Chongqing Medical University, Chongqing, China. FAU - Ran, Suzhen AU - Ran S AD - Department of Ultrasound, Chongqing Health Center for Women and Children, Chongqing, China. AD - Department of Ultrasound, Women and Children's Hospital of Chongqing Medical University, Chongqing, China. FAU - Zhang, Kun AU - Zhang K AD - Department of Ultrasound, Chongqing Health Center for Women and Children, Chongqing, China. AD - Department of Ultrasound, Women and Children's Hospital of Chongqing Medical University, Chongqing, China. LA - eng PT - Journal Article DEP - 20230615 PL - Switzerland TA - Front Pediatr JT - Frontiers in pediatrics JID - 101615492 PMC - PMC10310433 OTO - NOTNLM OT - congenital heart disease OT - echocardiography OT - infant OT - patent ductus arteriosus OT - premature COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2023/07/03 13:05 MHDA- 2023/07/03 13:06 PMCR- 2023/06/15 CRDT- 2023/07/03 11:29 PHST- 2023/04/02 00:00 [received] PHST- 2023/06/05 00:00 [accepted] PHST- 2023/07/03 13:06 [medline] PHST- 2023/07/03 13:05 [pubmed] PHST- 2023/07/03 11:29 [entrez] PHST- 2023/06/15 00:00 [pmc-release] AID - 10.3389/fped.2023.1198936 [doi] PST - epublish SO - Front Pediatr. 2023 Jun 15;11:1198936. doi: 10.3389/fped.2023.1198936. eCollection 2023.