PMID- 37401435 OWN - NLM STAT- MEDLINE DCOM- 20230705 LR - 20230705 IS - 1522-6662 (Electronic) IS - 1098-3511 (Linking) VI - 26 IP - 3 DP - 2023 Jun 14 TI - Application of Machine Learning Algorithms to Predict New-Onset Postoperative Atrial Fibrillation and Identify Risk Factors Following Isolated Valve Surgery. PG - E255-E263 LID - 10.1532/hsf.5341 [doi] AB - BACKGROUND: New-onset postoperative atrial fibrillation (POAF) is the most common complication after valvular surgery, but its etiology and risk factors are incompletely understood. This study investigates the benefits of machine learning methods in risk prediction and in identifying relative perioperative variables for POAF after valve surgery. METHODS: This retrospective study involved 847 patients, who underwent isolated valve surgery from January 2018 to September 2021 in our institution. We used machine learning algorithms to predict new-onset postoperative atrial fibrillation and to select relatively important variables from a set of 123 preoperative characteristics and intraoperative information. RESULTS: The support vector machine (SVM) model demonstrated the best area under the receiver operating characteristic (AUC) value of 0.786, followed by logistic regression (AUC = 0.745) and the Complement Naive Bayes (CNB) model (AUC = 0.672). Left atrium diameter, age, estimated glomerular filtration rate (eGFR), duration of cardiopulmonary bypass, New York Heart Association (NYHA) class III-IV, and preoperative hemoglobin were high-ranked variables. CONCLUSIONS: Risk models based on machine learning algorithms may be superior to traditional models, which were primarily based on logistic algorithms to predict the occurrence of POAF after valve surgery. Further prospective multicenter studies are needed to confirm the performance of SVM in predicting POAF. FAU - Zhu, Siming AU - Zhu S AD - Medical School of Chinese PLA, 100853 Beijing, China. 1440994567@qq.com. FAU - Che, Hebin AU - Che H AD - Department of Cardiovascular Surgery, The First Medical Center of Chinese PLA General Hospital, 100853 Beijing, China. maravich07@126.com. FAU - Fan, Yunlong AU - Fan Y AD - Medical School of Chinese PLA, 100853 Beijing, China. zhaoxiaoli15@163.com. FAU - Jiang, Shengli AU - Jiang S AD - Medical School of Chinese PLA, 100853 Beijing, China; Department of Cardiovascular Surgery, The First Medical Center of Chinese PLA General Hospital, 100853 Beijing, China. jiangsl301@sina.com. LA - eng PT - Journal Article DEP - 20230614 PL - United States TA - Heart Surg Forum JT - The heart surgery forum JID - 100891112 SB - IM MH - Humans MH - *Atrial Fibrillation/diagnosis/etiology MH - Retrospective Studies MH - Bayes Theorem MH - Predictive Value of Tests MH - Risk Factors MH - Postoperative Complications/epidemiology EDAT- 2023/07/04 06:42 MHDA- 2023/07/05 06:42 CRDT- 2023/07/04 04:32 PHST- 2022/12/01 00:00 [received] PHST- 2023/01/30 00:00 [accepted] PHST- 2023/07/05 06:42 [medline] PHST- 2023/07/04 06:42 [pubmed] PHST- 2023/07/04 04:32 [entrez] AID - 10.1532/hsf.5341 [doi] PST - epublish SO - Heart Surg Forum. 2023 Jun 14;26(3):E255-E263. doi: 10.1532/hsf.5341.