PMID- 37401972 OWN - NLM STAT- MEDLINE DCOM- 20230731 LR - 20230731 IS - 2731-7072 (Electronic) IS - 2731-7064 (Linking) VI - 62 IP - 8 DP - 2023 Aug TI - [Diagnostic work-up of benign prostatic hyperplasia : The German S2e-guideline 2023 part 1]. PG - 805-817 LID - 10.1007/s00120-023-02142-0 [doi] AB - BACKGROUND: Lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH; in German guidelines: benign prostatic syndrome [BPS]) is the most frequent urological disease in men and can result in a considerable deterioration of quality-of-life. BPS can be associated with LUTS, benign prostatic enlargement (BPE), and bladder outlet obstruction (BOO) or benign prostatic obstruction (BPO), respectively. The expert group on BPS of the German Society of Urology has re-evaluated the tests for the assessment of BPH and provides evidence-based recommendations. OBJECTIVES: Presentation and evidence-based rating of tests for the assessment of patients with BPS. MATERIALS AND METHODS: Summary and overview of chapters 5, 6, and 8 of the latest long version of the German S2e guideline on BPS. RESULTS: The diagnostic work-up should clarify (1) whether the complaints of the patient are caused by BPS, (2) how relevant the complaints are and whether treatment is necessary, (3) whether complications of the lower or upper urinary tract already exist, and (4) which treatment will be most suitable. Baseline assessment should be done in all BPS patients and include history, measurement of LUTS and quality-of-life, urinalysis, serum prostate-specific antigen, post-void residual, ultrasound of the lower urinary tract, including measurements of prostate volume, intravesical prostatic protrusion and detrusor wall thickness, and ultrasound of the upper urinary tract. Additional tests can follow when questions remain unanswered after baseline assessment. These optional tests include bladder diaries, uroflowmetry, serum creatinine, urethrocystoscopy, other noninvasive tests for the determination of BOO/BPO such as penile cuff test, condom catheter method and near-infrared spectroscopy, and other imagining tests such as X‑ray and MRI investigations. CONCLUSIONS: The updated German S2e guideline summarizes evidence-based recommendations on the diagnostic work-up, including the assessment of the BPS components BPE, LUTS, and BOO/BPO. CI - (c) 2023. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature. FAU - Oelke, Matthias AU - Oelke M AD - Klinik fur Urologie, Urologische Onkologie und Roboter-assistierte Chirurgie, St. Antonius-Hospital GmbH, Mollenweg 22, 48599, Gronau, Deutschland. matthias.oelke@st-antonius-gronau.de. FAU - Abt, S Dominik AU - Abt SD AD - Klinik fur Urologie, Spitalzentrum Biel, Biel, Schweiz. FAU - Becher, Klaus F AU - Becher KF AD - Klinik fur Rehabilitation, Klinik Wartenberg Professor Dr. Selmair GmbH & Co. KG, Wartenberg, Deutschland. FAU - Dreikorn, Kurt AU - Dreikorn K AD - Urologicum, Bremen, Deutschland. FAU - Madersbacher, Stephan AU - Madersbacher S AD - Klinik fur Urologie und Andrologie, Klinik Favoriten, Wien, Osterreich. FAU - Magistro, Giuseppe AU - Magistro G AD - Klinik fur Urologie, Asklepios Westklinikum GmbH, Hamburg, Deutschland. FAU - Michel, Martin C AU - Michel MC AD - Abteilung Pharmakologie, Johannes Gutenberg Universitat, Mainz, Deutschland. FAU - Muschter, Rolf AU - Muschter R AD - Urologische Abteilung, ALTA Klinik, Bielefeld, Deutschland. FAU - Reich, Oliver AU - Reich O AD - Urologische Privatpraxis Prof. Dr. Oliver Reich, Munchen, Deutschland. FAU - Rieken, Malte AU - Rieken M AD - Praxis alta uro, Basel, Schweiz. FAU - Salem, Johannes AU - Salem J AD - CUROS urologisches Zentrum, Klinik LINKS VOM RHEIN, Koln, Deutschland. AD - Klinik fur Urologie und Kinderurologie, Universitatsklinikum, Medizinische Hochschule Brandenburg Theodor Fontane, Brandenburg a.d. Havel, Deutschland. FAU - Schonburg, Sandra AU - Schonburg S AD - Universitatsklinik und Poliklinik fur Urologie, Martin-Luther Universitat Halle-Wittenberg, Halle (Saale), Deutschland. FAU - Hofner, Klaus AU - Hofner K AD - Klinik fur Urologie, Evangelisches Krankenhaus, Oberhausen, Deutschland. FAU - Bschleipfer, Thomas AU - Bschleipfer T AD - Klinik fur Urologie und Kinderurologie, Regiomed Klinikum, Coburg, Deutschland. LA - ger PT - English Abstract PT - Journal Article PT - Review TT - Diagnostik des benignen Prostatasyndroms : Die deutsche S2e-Leitlinie 2023 Teil 1. DEP - 20230704 PL - Germany TA - Urologie JT - Urologie (Heidelberg, Germany) JID - 9918384886606676 SB - IM MH - Male MH - Humans MH - *Prostatic Hyperplasia/diagnosis MH - Prostate/diagnostic imaging MH - Urinary Bladder/diagnostic imaging MH - Ultrasonography/adverse effects MH - *Lower Urinary Tract Symptoms/diagnosis MH - *Urinary Bladder Neck Obstruction/complications OTO - NOTNLM OT - Assessment OT - Benign prostatic hyperplasia OT - Bladder outlet obstruction OT - Guidelines OT - Lower urinary tract symptoms EDAT- 2023/07/04 13:08 MHDA- 2023/07/31 06:43 CRDT- 2023/07/04 11:05 PHST- 2023/06/07 00:00 [accepted] PHST- 2023/07/31 06:43 [medline] PHST- 2023/07/04 13:08 [pubmed] PHST- 2023/07/04 11:05 [entrez] AID - 10.1007/s00120-023-02142-0 [pii] AID - 10.1007/s00120-023-02142-0 [doi] PST - ppublish SO - Urologie. 2023 Aug;62(8):805-817. doi: 10.1007/s00120-023-02142-0. Epub 2023 Jul 4.