PMID- 37421257
OWN - NLM
STAT- Publisher
LR  - 20231221
IS  - 1942-7522 (Electronic)
IS  - 0145-5613 (Linking)
DP  - 2023 Jul 8
TI  - Correlation of Multiple Allergen Simultaneous Test with Nasal Provocation Test of 
      House Dust Mite.
PG  - 1455613231185065
LID - 10.1177/01455613231185065 [doi]
AB  - Objectives: Compared with the skin prick test, relationship between the multiple 
      allergen simultaneous test (MAST) and nasal provocation test (NPT) has rarely 
      been evaluated. We evaluated the relationship between the results of the MAST and 
      NPT against house dust mites in the Korean population. Methods: Medical records 
      of patients who underwent both MAST and NPT were reviewed. Positive MAST was 
      diagnosed when the levels of immunoglobulin E (IgE) specific for Dermatophagoides 
      farinae (DF) and Dermatophagoides pteronyssinus (DP) were >/=2 positivity or >/=0.70 
      IU/ml. During the NPT, changes in subjective symptoms, including nasal 
      obstruction, rhinorrhea, sneezing, itching, ocular discomfort, and peak nasal 
      inspiratory flow (PNIF), were measured. The correlation between NPT and MAST 
      results was statistically analyzed. Results: A total of 96 participants were 
      enrolled in this study: 26 were assigned to the MAST-positive group, and 70 were 
      assigned to the MAST-negative group. Changes in subjective symptoms before and 
      after the nasal allergen challenge were significantly associated with the MAST 
      results. Changes in PNIF before and after the nasal allergen challenge were also 
      significantly associated with the MAST results. We found that a cutoff value of 
      "a subjective total nasal symptom change" of more than 17.5 had a sensitivity of 
      68.6% and a specificity of 69.2%, while a cutoff value of "a PNIF change" of more 
      than 6.51 had a sensitivity of 67.1% and a specificity of 69.2%. Conclusion: NPT 
      was significantly associated with MAST, and further studies regarding the 
      relationship between NPT using various allergen conditions and MAST are 
      warranted.
FAU - Kim, Kyung Soo
AU  - Kim KS
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University 
      College of Medicine, Dongjak-gu, Seoul, South Korea.
FAU - Min, Hyun Jin
AU  - Min HJ
AUID- ORCID: 0000-0003-3075-1350
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University 
      College of Medicine, Dongjak-gu, Seoul, South Korea.
LA  - eng
PT  - Journal Article
DEP - 20230708
PL  - United States
TA  - Ear Nose Throat J
JT  - Ear, nose, & throat journal
JID - 7701817
SB  - IM
OTO - NOTNLM
OT  - allergic rhinitis
OT  - correlation
OT  - diagnosis
OT  - nasal provocation tests
COIS- Declaration of Conflicting InterestsThe author(s) declared no potential conflicts 
      of interest with respect to the research, authorship, and/or publication of this 
      article.
EDAT- 2023/07/08 19:41
MHDA- 2023/07/08 19:41
CRDT- 2023/07/08 07:13
PHST- 2023/07/08 19:41 [pubmed]
PHST- 2023/07/08 19:41 [medline]
PHST- 2023/07/08 07:13 [entrez]
AID - 10.1177/01455613231185065 [doi]
PST - aheadofprint
SO  - Ear Nose Throat J. 2023 Jul 8:1455613231185065. doi: 10.1177/01455613231185065.