PMID- 37428224 OWN - NLM STAT- Publisher LR - 20240210 IS - 1432-1068 (Electronic) IS - 1633-8065 (Print) IS - 1633-8065 (Linking) DP - 2023 Jul 10 TI - The trajectory of patient-reported outcomes and minimal clinically important differences in isolated and polytraumatic pelvis and acetabular fractures. LID - 10.1007/s00590-023-03631-w [doi] AB - PURPOSE: Patient-reported minimal clinically important differences (MCID) provide a standard to compare clinical outcomes. The purpose of this study was to calculate the MCID of PROMIS Physical Function (PF), Pain Interference (PI), Anxiety (AX), and Depression (DEP) scores in patients with pelvis and/or acetabular fractures. METHODS: All patients with operatively treated pelvic and/or acetabular fractures were identified. Patients were categorized as either only pelvis and/or acetabular fractures (PA) or polytrauma (PT). PROMIS PF, PI, AX, and DEP scores were evaluated at 3-month, 6-month, and 12-month intervals. Distribution-based MCID and anchor-based MCID were calculated for the overall cohort, PA, and PT groups. RESULTS: The overall distribution-based MCIDs were PF (5.19), PI (3.97), AX (4.33), and DEP (4.41). The overall anchor-based MCIDs were PF (7.18), PI (8.03), AX (5.85), DEP (5.00). The percentage of patients achieving MCID for AX was 39.8-54% at 3 months and 32.7-56% at 12 months. The percentage of patients achieving MCID for DEP was 35.7-39.3% at 3 months and 32.1-35.7% at 12 months. The PT group had worse PROMIS PF scores than the PA group at all time points [post-operative, 3-month, 6-month, and 12-month scores, (28.3 (6.3) vs. 26.8 (6.8) P = 0.016), (38.1 (9.2) vs. 35.0 (8.7) P = 0.037), (42.8 (8.2) vs. 39 (9.6) P = 0.015), (46.2 (9.7) vs. 41.2 (9.7) P = 0.011)]. CONCLUSION: An overall MCID for PROMIS PF was 5.19-7.18, PROMIS PI 3.97-8.03, PROMIS AX of 4.33-5.85, and PROMIS DEP of 4.41-5.00. The PT group had worse PROMIS PF at all time points. The percentage of patients achieving MCID for AX and DEP plateaued at 3 months post-operatively. LEVEL OF EVIDENCE: Level IV. CI - (c) 2023. The Author(s), under exclusive licence to Springer-Verlag France SAS, part of Springer Nature. FAU - Thorne, Tyler AU - Thorne T AUID- ORCID: 0000-0001-8305-6306 AD - Department of Orthopaedic Surgery, University of Utah, 590 Wakara Way, Salt Lake City, UT, 84108, USA. FAU - Cizik, Amy AU - Cizik A AD - Department of Orthopaedic Surgery, University of Utah, 590 Wakara Way, Salt Lake City, UT, 84108, USA. FAU - Dong, Willie AU - Dong W AD - Department of Orthopaedic Surgery, University of Utah, 590 Wakara Way, Salt Lake City, UT, 84108, USA. FAU - Da Silva, Zarek AU - Da Silva Z AD - Department of Orthopaedic Surgery, University of Utah, 590 Wakara Way, Salt Lake City, UT, 84108, USA. FAU - Wei, Yingjia AU - Wei Y AD - Division of Epidemiology, Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA. FAU - Zhang, Yue AU - Zhang Y AD - Division of Epidemiology, Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA. FAU - Haller, Justin M AU - Haller JM AUID- ORCID: 0000-0002-8269-3925 AD - Department of Orthopaedic Surgery, University of Utah, 590 Wakara Way, Salt Lake City, UT, 84108, USA. justin.haller@hsc.utah.edu. LA - eng GR - UL1 RR025764/RR/NCRR NIH HHS/United States GR - UL1 TR002538/TR/NCATS NIH HHS/United States GR - UL1 TR000105/TR/NCATS NIH HHS/United States GR - L30 AR077934/AR/NIAMS NIH HHS/United States GR - UL1 TR001067/TR/NCATS NIH HHS/United States PT - Journal Article DEP - 20230710 PL - France TA - Eur J Orthop Surg Traumatol JT - European journal of orthopaedic surgery & traumatology : orthopedie traumatologie JID - 9518037 SB - IM PMC - PMC10776809 MID - NIHMS1930807 OTO - NOTNLM OT - Acetabular OT - Anxiety OT - Depression OT - MCID OT - PROMIS OT - Pain OT - Pelvic OT - Physical function OT - Psychometric analysis EDAT- 2023/07/10 13:05 MHDA- 2023/07/10 13:05 PMCR- 2025/01/10 CRDT- 2023/07/10 11:06 PHST- 2023/05/22 00:00 [received] PHST- 2023/06/17 00:00 [accepted] PHST- 2025/01/10 00:00 [pmc-release] PHST- 2023/07/10 13:05 [medline] PHST- 2023/07/10 13:05 [pubmed] PHST- 2023/07/10 11:06 [entrez] AID - 10.1007/s00590-023-03631-w [pii] AID - 10.1007/s00590-023-03631-w [doi] PST - aheadofprint SO - Eur J Orthop Surg Traumatol. 2023 Jul 10:10.1007/s00590-023-03631-w. doi: 10.1007/s00590-023-03631-w.