PMID- 37429439 OWN - NLM STAT- MEDLINE DCOM- 20230911 LR - 20230916 IS - 1874-1754 (Electronic) IS - 0167-5273 (Linking) VI - 390 DP - 2023 Nov 1 TI - Two-incision totally thoracoscopic mitral valve repair combined with radiofrequency atrial fibrillation ablation in rheumatic mitral valve disease: Early results of a case series of 43 consecutive patients. PG - 131158 LID - S0167-5273(23)00965-8 [pii] LID - 10.1016/j.ijcard.2023.131158 [doi] AB - BACKGROUND: Few studies have reported the outcomes of two-incision total thoracoscopic mitral valve repair (MVr) and concomitant radiofrequency atrial fibrillation ablation (RAFA) in patients with rheumatic mitral valve disease and atrial fibrillation (AF). METHODS: We retrospectively analyzed 43 consecutive patients who underwent MVr and RAFA through two-incision total thoracoscopic technique from October 2018 to June 2022. We collected data on baseline characteristics, perioperative outcomes, and early-term results. RESULTS: The mean age was 55.67 +/- 7.64 years and 29 (67.4%) patients had New York Heart Association (NYHA) class III or IV. The mean cardiopulmonary bypass (CPB) time was 115.56 +/- 8.53 min and aortic clamping time was 81.42 +/- 7.54 min. There were no in-hospital deaths or strokes. The mean preoperative mitral valve orifice area (MVOA) was 0.95 (0.84-1.16) cm2 and increased to 2.56 (2.41-2.87) cm2 at discharge and 2.54 (2.44-2.76) cm2 at 3 months after surgery (P < .001). At discharge, 32 (74.4%) patients were in sinus rhythm, 7 (20.9%) were in junctional or atrial flutter rhythm, and 4 (9.3%) remained in AF. At 6 months, 35 (81.4%) patients were in sinus rhythm, 5 (11.63%) were in junctional or atrial flutter rhythm, and 3 (4.7%) were in AF. CONCLUSIONS: Two-incision total thoracoscopic MVr and RAFA is a safe and effective procedure that can improve the MVOA and promote conversion of AF to sinus rhythm in patients with rheumatic mitral valve disease and AF. Further studies with larger sample size and longer follow-up are needed to confirm the long-term benefits of this approach. CI - Copyright (c) 2023 Elsevier B.V. All rights reserved. FAU - Xu, Zheng AU - Xu Z AD - Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou 350001, PR China; Key Laboratory of Cardio-Thoracic Surgery, Fujian Medical University, Fujian Province University, Fuzhou 350001, PR China. FAU - Dai, Xiao-Fu AU - Dai XF AD - Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou 350001, PR China; Key Laboratory of Cardio-Thoracic Surgery, Fujian Medical University, Fujian Province University, Fuzhou 350001, PR China. FAU - Lin, Feng AU - Lin F AD - Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou 350001, PR China. FAU - Chen, Liang-Wan AU - Chen LW AD - Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou 350001, PR China; Key Laboratory of Cardio-Thoracic Surgery, Fujian Medical University, Fujian Province University, Fuzhou 350001, PR China. FAU - Lin, Zhi-Qin AU - Lin ZQ AD - Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou 350001, PR China. Electronic address: zhiqinemail@163.com. LA - eng PT - Journal Article DEP - 20230708 PL - Netherlands TA - Int J Cardiol JT - International journal of cardiology JID - 8200291 SB - IM MH - Humans MH - Middle Aged MH - Mitral Valve/diagnostic imaging/surgery MH - *Atrial Fibrillation/diagnosis/surgery/complications MH - Retrospective Studies MH - *Atrial Flutter/surgery MH - Treatment Outcome MH - *Heart Valve Diseases/complications/surgery MH - *Rheumatic Heart Disease/complications/diagnosis/surgery MH - *Catheter Ablation/methods MH - Thoracoscopy OTO - NOTNLM OT - Atrial fibrillation OT - Radiofrequency ablation OT - Rheumatic mitral valve disease OT - Total thoracoscopic mitral valve repair COIS- Declaration of Competing Interest None declared. EDAT- 2023/07/11 01:07 MHDA- 2023/09/11 06:42 CRDT- 2023/07/10 19:23 PHST- 2023/04/16 00:00 [received] PHST- 2023/06/07 00:00 [revised] PHST- 2023/07/05 00:00 [accepted] PHST- 2023/09/11 06:42 [medline] PHST- 2023/07/11 01:07 [pubmed] PHST- 2023/07/10 19:23 [entrez] AID - S0167-5273(23)00965-8 [pii] AID - 10.1016/j.ijcard.2023.131158 [doi] PST - ppublish SO - Int J Cardiol. 2023 Nov 1;390:131158. doi: 10.1016/j.ijcard.2023.131158. Epub 2023 Jul 8.