PMID- 37430404
OWN - NLM
STAT- Publisher
LR  - 20231013
IS  - 2234-2400 (Print)
IS  - 2234-2443 (Electronic)
IS  - 2234-2400 (Linking)
VI  - 56
IP  - 5
DP  - 2023 Sep
TI  - Anesthesia care provider sedation versus conscious sedation for endoscopic 
      ultrasound-guided tissue acquisition: a retrospective cohort study.
PG  - 658-665
LID - 10.5946/ce.2023.006 [doi]
AB  - BACKGROUND/AIMS: We aimed to study the effects of sedation on endoscopic 
      ultrasound-guided tissue acquisition. METHODS: We conducted a retrospective study 
      evaluating the role of sedation in endoscopic ultrasound-guided tissue 
      acquisition by comparing two groups: anesthesia care provider (ACP) sedation and 
      endoscopist-directed conscious sedation (CS). RESULTS: Technical success was 
      achieved in 219/233 (94.0%) in the ACP group and 114/136 (83.8%) in the CS group 
      (p=0.0086). In multivariate analysis, the difference in technical success between 
      the two groups was not significant (adjusted odds ratio [aOR], 0.5; 95% 
      confidence interval [CI], 0.234-1.069; p=0.0738). A successful diagnostic yield 
      was present in 146/196 (74.5%) in the ACP group and 66/106 (62.3%) in the CS 
      group, respectively (p=0.0274). In multivariate analysis, the difference in 
      diagnostic yield between the two groups was not significant (aOR, 0.643; 95% CI, 
      0.356-1.159; p=0.142). A total of 33 adverse events (AEs) were observed. The 
      incidence of AEs was significantly lower in the CS group (5/33 CS vs. 28/33 ACP; 
      OR, 0.281; 95% CI, 0.095-0.833; p=0.022). CONCLUSION: CS provided equivalent 
      technical success and diagnostic yield for malignancy in endoscopic 
      ultrasound-guided tissue acquisition. Increased AEs were associated with 
      anesthesia for the endoscopic ultrasound-guided tissue acquisition.
FAU - Shaha, Sneha
AU  - Shaha S
AD  - Department of Medicine, Loma Linda University Medical Center, Loma Linda, CA, 
      USA.
FAU - Gao, Yinglin
AU  - Gao Y
AD  - Department of Medicine, Loma Linda University Medical Center, Loma Linda, CA, 
      USA.
FAU - Peng, Jiahao
AU  - Peng J
AD  - Department of Medicine, Loma Linda University Medical Center, Loma Linda, CA, 
      USA.
FAU - Che, Kendrick
AU  - Che K
AD  - Division of Gastroenterology and Hepatology, Loma Linda University Medical 
      Center, Loma Linda, CA, USA.
FAU - Kim, John J
AU  - Kim JJ
AD  - Division of Gastroenterology and Hepatology, Loma Linda University Medical 
      Center, Loma Linda, CA, USA.
FAU - Skef, Wasseem
AU  - Skef W
AD  - Division of Gastroenterology and Hepatology, Department of Medicine, Baylor 
      College of Medicine, Houston, TX, USA.
LA  - eng
PT  - Journal Article
DEP - 20230703
PL  - Korea (South)
TA  - Clin Endosc
JT  - Clinical endoscopy
JID - 101576886
PMC - PMC10565438
OTO - NOTNLM
OT  - Anesthesia
OT  - Conscious sedation
OT  - Endoscopic ultrasound-guided fine needle aspiration
OT  - General anesthesia
COIS- Conflicts of Interest The authors have no potential conflicts of interest.
EDAT- 2023/07/11 01:08
MHDA- 2023/07/11 01:08
PMCR- 2023/09/01
CRDT- 2023/07/10 23:49
PHST- 2022/12/02 00:00 [received]
PHST- 2023/02/12 00:00 [accepted]
PHST- 2023/07/11 01:08 [pubmed]
PHST- 2023/07/11 01:08 [medline]
PHST- 2023/07/10 23:49 [entrez]
PHST- 2023/09/01 00:00 [pmc-release]
AID - ce.2023.006 [pii]
AID - ce-2023-006 [pii]
AID - 10.5946/ce.2023.006 [doi]
PST - ppublish
SO  - Clin Endosc. 2023 Sep;56(5):658-665. doi: 10.5946/ce.2023.006. Epub 2023 Jul 3.