PMID- 37431350 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230718 IS - 2168-8184 (Print) IS - 2168-8184 (Electronic) IS - 2168-8184 (Linking) VI - 15 IP - 6 DP - 2023 Jun TI - Early Major Adverse Cardiovascular Event in a Patient With Chronic Kidney Disease: A Case Report. PG - e40161 LID - 10.7759/cureus.40161 [doi] LID - e40161 AB - Acute coronary syndrome (ACS) is common in people with chronic kidney disease (CKD) and is linked to poor short- and long-term outcomes. The diagnosis of myocardial infarction is challenging in patients with CKD as they have baseline elevated troponin levels. To date, there are no widely accepted guidelines to suggest what is a clinically significant change in troponin levels in these patients. We report a case of a patient with CKD who presented with chest pain to the emergency department (ED). His baseline troponin was high; however, the delta change was 11%. He was discharged from the ED for outpatient follow-up, but within 36 hours, he had significant ST elevation myocardial infarction (STEMI) with unstable hemodynamics and acute heart failure requiring urgent intubation and coronary revascularization. This case highlights the gap in clinical knowledge and practice in a relatively not uncommon presentation in emergency departments. CI - Copyright (c) 2023, Saleh Juman Alseiari et al. FAU - Saleh Juman Alseiari, Saleh AU - Saleh Juman Alseiari S AD - Department of Emergency Medicine, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, ARE. FAU - Fadil Ali Al Thehli, Reem AU - Fadil Ali Al Thehli R AD - Department of Emergency Medicine, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, ARE. FAU - Farooq, Munawar AU - Farooq M AD - Department of Internal Medicine, Emergency Medicine Section, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, ARE. LA - eng PT - Case Reports DEP - 20230608 PL - United States TA - Cureus JT - Cureus JID - 101596737 PMC - PMC10329737 OTO - NOTNLM OT - acs OT - acute coronary syndromes OT - acute heart failure OT - cardiac biomarkers OT - chest pain OT - chronic kidney disease OT - mace OT - major adverse cardiovascular event OT - myocardial infarction OT - troponin rise COIS- The authors have declared that no competing interests exist. EDAT- 2023/07/11 06:42 MHDA- 2023/07/11 06:43 PMCR- 2023/06/08 CRDT- 2023/07/11 03:35 PHST- 2023/06/08 00:00 [accepted] PHST- 2023/07/11 06:43 [medline] PHST- 2023/07/11 06:42 [pubmed] PHST- 2023/07/11 03:35 [entrez] PHST- 2023/06/08 00:00 [pmc-release] AID - 10.7759/cureus.40161 [doi] PST - epublish SO - Cureus. 2023 Jun 8;15(6):e40161. doi: 10.7759/cureus.40161. eCollection 2023 Jun.