PMID- 37434338
OWN - NLM
STAT- MEDLINE
DCOM- 20230713
LR  - 20230718
IS  - 1525-6065 (Electronic)
IS  - 1064-1955 (Linking)
VI  - 42
IP  - 1
DP  - 2023 Dec
TI  - Oral nifedipine may be a preferential option for treating acute severe 
      hypertension during pregnancy: a meta-analysis.
PG  - 2209637
LID - 10.1080/10641955.2023.2209637 [doi]
AB  - AIM: To compare oral nifedipine and intravenous labetalol in the treatment of 
      acute severe hypertension in pregnancy (SHP). METHODS: The primary outcomes were 
      the required time to achieve target blood pressure (RTATBP), systolic blood 
      pressure (SBP) and diastolic BP (DBP) after treatment, secondary outcomes were 
      the number of doses (NoD) and adverse events (AEs). RESULTS: There was no 
      difference between oral nifedipine and intravenous labetalol in SBP, DBP, and AE. 
      However, oral nifedipine provided less RTATBP and NoD. CONCLUSION: Oral 
      nifedipine was associated with less RTATBP and NoD and otherwise did not differ 
      from intravenous labetalol.
FAU - Ou, Minghui
AU  - Ou M
AD  - Department of Vascular Surgery, Qingdao Municipal Hospital, Qingdao, China.
FAU - Zhang, Futao
AU  - Zhang F
AD  - Department of Vascular Surgery, The People's Hospital of Qingdao Chengyang 
      District, Qingdao, China.
FAU - Cui, Shichao
AU  - Cui S
AD  - Department of Vascular Surgery, Qingdao Municipal Hospital, Qingdao, China.
FAU - Zhao, Shibo
AU  - Zhao S
AD  - Department of Vascular Surgery, Qingdao Municipal Hospital, Qingdao, China.
FAU - Yu, Yan
AU  - Yu Y
AD  - Department of Vascular Surgery, Qingdao Municipal Hospital, Qingdao, China.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PL  - England
TA  - Hypertens Pregnancy
JT  - Hypertension in pregnancy
JID - 9421297
RN  - R5H8897N95 (Labetalol)
RN  - I9ZF7L6G2L (Nifedipine)
SB  - IM
MH  - Female
MH  - Pregnancy
MH  - Humans
MH  - *Labetalol/therapeutic use
MH  - Nifedipine/therapeutic use
MH  - Blood Pressure
MH  - *Hypertension, Pregnancy-Induced/drug therapy
OTO - NOTNLM
OT  - labetalol
OT  - meta-analysis
OT  - nifedipine
OT  - pregnancy-induced hypertension
EDAT- 2023/07/12 06:42
MHDA- 2023/07/13 06:42
CRDT- 2023/07/12 01:23
PHST- 2023/07/13 06:42 [medline]
PHST- 2023/07/12 06:42 [pubmed]
PHST- 2023/07/12 01:23 [entrez]
AID - 10.1080/10641955.2023.2209637 [doi]
PST - ppublish
SO  - Hypertens Pregnancy. 2023 Dec;42(1):2209637. doi: 10.1080/10641955.2023.2209637.