PMID- 37434671
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230928
IS  - 0165-8107 (Print)
IS  - 1744-506X (Electronic)
IS  - 0165-8107 (Linking)
VI  - 47
IP  - 4
DP  - 2023
TI  - Differentiating Occult Neuroretinitis and Non-Arteritic Anterior Ischaemic Optic 
      Neuropathy: Clinical and Optical Coherence Tomography Characteristics.
PG  - 208-217
LID - 10.1080/01658107.2023.2220778 [doi]
AB  - We report clinical and optical coherence tomography (OCT) differences among 
      patients with occult neuroretinitis and non-arteritic anterior ischaemic optic 
      neuropathy (NAAION). We retrospectively reviewed records of patients with a final 
      diagnosis of occult neuroretinitis and NAAION seen at our institute. Data were 
      collected regarding patient demographics, clinical features, concomitant systemic 
      risk factors, visual function, and optical coherence tomography (OCT) findings at 
      presentation and subsequent follow-up. Fourteen and 16 patients were diagnosed to 
      have occult neuroretinitis and NAAION, respectively. Patients with NAAION were 
      slightly older (median age 49, inter-quartile range [IQR]: 45-54 years, versus 
      41, IQR: 31-50 years) than patients with neuroretinitis. Seventy-five per cent of 
      patients with NAAION were male versus 43% with neuroretinitis (p = 0.07). 
      Systemic risk factors were present in 87.5% of patients with NAAION versus 21.4% 
      in patients with neuroretinitis (p = 0.001). At presentation, all patients 
      presented with blurred vision, had similar visual function, and had optic disc 
      oedema. In addition, none of the patients had evident retinitis lesions, but 10 
      (71%) showed evident retinitis lesion at follow-up. Neuroretinitis patients had 
      more often vitreous cells (64% versus 6%, p = 0.001), and subretinal fluid (78.6% 
      versus 37.5%, p = 0.03) than the patients with NAAION. In summary, NAAION 
      patients tended to be slightly older, more often male, and had associated 
      systemic diseases more often than those with neuroretinitis. Neuroretinitis 
      patients more often had posterior vitreous cells and subretinal fluid on OCT. 
      However, larger prospective studies are needed.
CI  - (c) 2023 Taylor & Francis Group, LLC.
FAU - Ganatra, Snehal
AU  - Ganatra S
AD  - Child Sight Institute, Nimmagadda Prasad Children's Eye Care Centre, L V Prasad 
      Eye Institute, Visakhapatnam, India.
FAU - Panchal, Bhavik
AU  - Panchal B
AD  - Vitreoretina and Uveitis Services, L V Prasad Eye Institute, Visakhapatnam, 
      India.
FAU - Pathengay, Avinash
AU  - Pathengay A
AD  - Vitreoretina and Uveitis Services, L V Prasad Eye Institute, Visakhapatnam, 
      India.
FAU - Sachdeva, Virender
AU  - Sachdeva V
AD  - Child Sight Institute, Nimmagadda Prasad Children's Eye Care Centre, L V Prasad 
      Eye Institute, Visakhapatnam, India.
LA  - eng
PT  - Journal Article
DEP - 20230707
PL  - England
TA  - Neuroophthalmology
JT  - Neuro-ophthalmology (Aeolus Press)
JID - 8408966
PMC - PMC10332201
OTO - NOTNLM
OT  - Occult
OT  - differentiating
OT  - neuroretinitis
OT  - non-arteritic anterior ischaemic optic neuropathy
OT  - optical coherence tomography
COIS- No potential conflict of interest was reported by the authors.
EDAT- 2023/07/12 06:42
MHDA- 2023/07/12 06:43
PMCR- 2024/07/07
CRDT- 2023/07/12 03:45
PHST- 2024/07/07 00:00 [pmc-release]
PHST- 2023/07/12 06:43 [medline]
PHST- 2023/07/12 06:42 [pubmed]
PHST- 2023/07/12 03:45 [entrez]
AID - 2220778 [pii]
AID - 10.1080/01658107.2023.2220778 [doi]
PST - epublish
SO  - Neuroophthalmology. 2023 Jul 7;47(4):208-217. doi: 10.1080/01658107.2023.2220778. 
      eCollection 2023.