PMID- 37438689
OWN - NLM
STAT- MEDLINE
DCOM- 20230714
LR  - 20230718
IS  - 1471-2431 (Electronic)
IS  - 1471-2431 (Linking)
VI  - 23
IP  - 1
DP  - 2023 Jul 12
TI  - Congenital heart diseases with airway stenosis: a predictive nomogram to 
      risk-stratify patients without airway intervention.
PG  - 351
LID - 10.1186/s12887-023-04160-5 [doi]
LID - 351
AB  - BACKGROUND: This study focused on congenital heart disease (CHD) patients 
      complicated with airway stenosis (AS) without airway intervention and aimed to 
      identify the patients with potential risks. METHODS: Patients diagnosed with CHD 
      and AS were enrolled in this retrospective study. The primary outcome was defined 
      as a postoperative mechanical ventilation duration of more than two weeks. We 
      constructed a prediction model to predict the risk of prolonged mechanical 
      ventilation (PMV). RESULTS: A total of 185 patients diagnosed with CHD and AS in 
      Fuwai Hospital from July 2009 to December 2022 were included in the study. Weight 
      at CHD surgery, cardiopulmonary bypass (CPB) duration, complex CHD and comorbid 
      tracheobronchomalacia were identified as risk factors and included in the model. 
      The ROC curve showed a good distinguishing ability, with an AUC of 0.847 (95% CI: 
      0.786-0.908). According to the optimal cut-off value of the ROC curve, patients 
      were divided into high- and low-risk groups, and the subsequent analysis showed 
      significant differences in peri-operative characteristics and in-hospital deaths. 
      CONCLUSIONS: With the predictive model, several factors could be used to assess 
      the risky patients with PMV. More attention should be paid to these patients by 
      early identification and routine surveillance.
CI  - (c) 2023. The Author(s).
FAU - He, Qiyu
AU  - He Q
AD  - Pediatric Cardiac Surgery Centre, National Centre for Cardiovascular Diseases, 
      State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy 
      of Medical Sciences, Peking Union Medical College, Beijing, 100037, China.
FAU - Liu, Yuze
AU  - Liu Y
AD  - Pediatric Cardiac Surgery Centre, National Centre for Cardiovascular Diseases, 
      State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy 
      of Medical Sciences, Peking Union Medical College, Beijing, 100037, China.
FAU - Dou, Zheng
AU  - Dou Z
AD  - Pediatric Cardiac Surgery Centre, National Centre for Cardiovascular Diseases, 
      State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy 
      of Medical Sciences, Peking Union Medical College, Beijing, 100037, China.
FAU - Ma, Kai
AU  - Ma K
AD  - Pediatric Cardiac Surgery Centre, National Centre for Cardiovascular Diseases, 
      State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy 
      of Medical Sciences, Peking Union Medical College, Beijing, 100037, China.
FAU - Li, Shoujun
AU  - Li S
AD  - Pediatric Cardiac Surgery Centre, National Centre for Cardiovascular Diseases, 
      State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy 
      of Medical Sciences, Peking Union Medical College, Beijing, 100037, China. 
      drlishoujunfw@163.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230712
PL  - England
TA  - BMC Pediatr
JT  - BMC pediatrics
JID - 100967804
SB  - IM
MH  - Humans
MH  - Constriction, Pathologic
MH  - *Nomograms
MH  - Retrospective Studies
MH  - *Heart Defects, Congenital/complications/surgery
MH  - Hospitals
PMC - PMC10337114
OTO - NOTNLM
OT  - Airway stenosis
OT  - Congenital heart diseases
OT  - Mechanical ventilation
OT  - Nomogram
OT  - Predictive model
COIS- The authors declare no competing interests.
EDAT- 2023/07/13 01:06
MHDA- 2023/07/14 13:06
PMCR- 2023/07/12
CRDT- 2023/07/12 23:40
PHST- 2023/05/15 00:00 [received]
PHST- 2023/06/26 00:00 [accepted]
PHST- 2023/07/14 13:06 [medline]
PHST- 2023/07/13 01:06 [pubmed]
PHST- 2023/07/12 23:40 [entrez]
PHST- 2023/07/12 00:00 [pmc-release]
AID - 10.1186/s12887-023-04160-5 [pii]
AID - 4160 [pii]
AID - 10.1186/s12887-023-04160-5 [doi]
PST - epublish
SO  - BMC Pediatr. 2023 Jul 12;23(1):351. doi: 10.1186/s12887-023-04160-5.