PMID- 37439707
OWN - NLM
STAT- MEDLINE
DCOM- 20231108
LR  - 20231108
IS  - 1944-7922 (Electronic)
IS  - 1060-3271 (Linking)
VI  - 106
IP  - 6
DP  - 2023 Nov 2
TI  - Quantitative Determination of Organophosphorus, Pyrethroid, and Dithiolane 
      Pesticide Residues in Brown Rice Using Supercritical Fluid Extraction and Liquid 
      Chromatography-Tandem Mass Spectrometry.
PG  - 1532-1541
LID - 10.1093/jaoacint/qsad080 [doi]
AB  - BACKGROUND: Supercritical fluid extraction (SFE) is a fast, versatile, and 
      solvent-efficient automatic extraction method. Despite its advantages, the 
      results of our proficiency tests imply that the applicability assessments of SFE 
      for pesticide residues were insufficient. OBJECTIVE: In this study, as analytical 
      method using SFE was optimized and validated by testing the incurred and 
      fortified brown rice samples with organophosphorus (OP), pyrethroid (PYR), and 
      dithiolane (DIT) pesticides. METHOD: A validation study using the incurred sample 
      with etofenprox, fenitrothion, and isoprothiolane was performed by comparing the 
      analytical results obtained using the SFE and solid-liquid extraction with 
      homogenization (SLE), which is a well-validated official multi-residue extraction 
      method. The tests on the fortified samples were also performed for seven 
      pesticide residues, chlorpyrifos, diazinon, O-ethyl O-4-nitrophenyl 
      phenylphosphonothioate (EPN), etofenprox, fenitrothion, isoxathion, and 
      isoprothiolane, at three fortification levels, 0.001, 0.01, and 0.1 mg/kg. 
      RESULTS: In the test on the incurred samples, optimized SFE-to-SLE analytical 
      values (CSFE/CSLE) were 99.2-100.1%, with RSD lower than 3%. In contrast, the 
      analytical-to-spiked concentrations in the tests on the fortified samples were 
      96.4-105.0%, with RSD lower than 8.8%. CONCLUSIONS: These results indicate that 
      the proposed SFE method, which is well validated with the incurred brown rice 
      sample, is useful for determining OP, PYR, and DIT pesticide residues in brown 
      rice. HIGHLIGHTS: The proposed SFE method satisfies EU and Japanese maximum 
      residue limits (MRLs). The consumption of solvent can be reduced to one-fourth of 
      that of SLE using the proposed SFE method.
CI  - (c) The Author(s) 2023. Published by Oxford University Press on behalf of AOAC 
      INTERNATIONAL. All rights reserved. For permissions, please email: 
      journals.permissions@oup.com.
FAU - Nakamura, Keisuke
AU  - Nakamura K
AUID- ORCID: 0000-0001-7782-1040
AD  - National Metrology Institute of Japan (NMIJ), National Institute of Advanced 
      Industrial Science and Technology (AIST), Central 3, 1-1-1 Umezono, Tsukuba, 
      Ibaraki 305-8563, Japan.
FAU - Otake, Takamitsu
AU  - Otake T
AUID- ORCID: 0000-0001-8213-996X
AD  - National Metrology Institute of Japan (NMIJ), National Institute of Advanced 
      Industrial Science and Technology (AIST), Central 3, 1-1-1 Umezono, Tsukuba, 
      Ibaraki 305-8563, Japan.
FAU - Hanari, Nobuyasu
AU  - Hanari N
AUID- ORCID: 0000-0003-3093-2450
AD  - National Metrology Institute of Japan (NMIJ), National Institute of Advanced 
      Industrial Science and Technology (AIST), Central 3, 1-1-1 Umezono, Tsukuba, 
      Ibaraki 305-8563, Japan.
LA  - eng
GR  - Health and Labour Sciences Research/
GR  - 20KA1001/Ministry of Health, Labour, and Welfare/
GR  - Japan Society for the Promotion of Science/
GR  - KAKENHI/
GR  - JP21 K14657/Grant-in-Aid for Early-Career Scientists/
PT  - Journal Article
PL  - England
TA  - J AOAC Int
JT  - Journal of AOAC International
JID - 9215446
RN  - 0 (Pesticide Residues)
RN  - 0LD7P9153C (ethofenprox)
RN  - 88HCS898G6 (isoprothiolane)
RN  - W8M4X3Y7ZY (Fenitrothion)
RN  - 0 (Pyrethrins)
RN  - 0 (Solvents)
SB  - IM
MH  - *Pesticide Residues/analysis
MH  - *Oryza
MH  - *Chromatography, Supercritical Fluid/methods
MH  - Tandem Mass Spectrometry
MH  - Fenitrothion/analysis
MH  - *Pyrethrins/analysis
MH  - Chromatography, Liquid/methods
MH  - Solvents/chemistry
EDAT- 2023/07/13 12:32
MHDA- 2023/11/08 06:44
CRDT- 2023/07/13 10:13
PHST- 2022/11/29 00:00 [received]
PHST- 2023/06/26 00:00 [revised]
PHST- 2023/06/26 00:00 [accepted]
PHST- 2023/11/08 06:44 [medline]
PHST- 2023/07/13 12:32 [pubmed]
PHST- 2023/07/13 10:13 [entrez]
AID - 7223728 [pii]
AID - 10.1093/jaoacint/qsad080 [doi]
PST - ppublish
SO  - J AOAC Int. 2023 Nov 2;106(6):1532-1541. doi: 10.1093/jaoacint/qsad080.