PMID- 37441027
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230718
IS  - 2046-2069 (Electronic)
IS  - 2046-2069 (Linking)
VI  - 13
IP  - 30
DP  - 2023 Jul 7
TI  - Morphologies, mechanical and in vitro behaviors of DLP-based 3D printed HA 
      scaffolds with different structural configurations.
PG  - 20830-20838
LID - 10.1039/d3ra03080f [doi]
AB  - In the field of bone engineering, porous ceramic scaffolds are in great demand 
      for repairing bone defects. In this study, hydroxyapatite (HA) ceramic scaffolds 
      with three different structural configurations, including the body-centered cubic 
      (BCC), the face-centered cubic (FCC), and the triply periodic minimal surface 
      (TPMS), were fabricated through digital light processing (DLP) based 3D printing 
      technologies. The effects of the structural configurations on the morphologies 
      and mechanical properties of the DLP-based 3D printed HA scaffolds were 
      characterized. Furthermore, in vitro evaluations, including in vitro 
      cytocompatibility, bone alkaline phosphatase (ALP) activity assay, and protein 
      expression, were conducted to assess HA scaffold behavior. Finally, we evaluated 
      the effects of structural configurations from these aspects and selected the most 
      suitable structure of HA scaffold for bone repair.
CI  - This journal is (c) The Royal Society of Chemistry.
FAU - Liu, Ke
AU  - Liu K
AD  - Center of Stomatology, China-Japan Friendship Hospital Beijing 100029 China 
      drxubaohua@163.com.
AD  - Graduate School of Peking Union Medical College, Chinese Academy of Medical 
      Sciences and Peking Union Medical College Beijing 100029 China.
FAU - Zhou, Qing
AU  - Zhou Q
AD  - Beijing Key Laboratory of Lightweight Multi-functional Composite Materials and 
      Structure, Beijing Institute of Technology Beijing 100081 China 
      herujie@bit.edu.cn.
FAU - Zhang, Xueqin
AU  - Zhang X
AD  - Beijing Key Laboratory of Lightweight Multi-functional Composite Materials and 
      Structure, Beijing Institute of Technology Beijing 100081 China 
      herujie@bit.edu.cn.
FAU - Ma, Lili
AU  - Ma L
AD  - Center of Stomatology, China-Japan Friendship Hospital Beijing 100029 China 
      drxubaohua@163.com.
FAU - Xu, Baohua
AU  - Xu B
AD  - Center of Stomatology, China-Japan Friendship Hospital Beijing 100029 China 
      drxubaohua@163.com.
FAU - He, Rujie
AU  - He R
AUID- ORCID: 0000-0003-2498-2363
AD  - Beijing Key Laboratory of Lightweight Multi-functional Composite Materials and 
      Structure, Beijing Institute of Technology Beijing 100081 China 
      herujie@bit.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20230711
PL  - England
TA  - RSC Adv
JT  - RSC advances
JID - 101581657
PMC - PMC10333813
COIS- There are no conflicts to declare.
EDAT- 2023/07/13 19:15
MHDA- 2023/07/13 19:16
PMCR- 2023/07/11
CRDT- 2023/07/13 15:18
PHST- 2023/05/09 00:00 [received]
PHST- 2023/07/03 00:00 [accepted]
PHST- 2023/07/13 19:16 [medline]
PHST- 2023/07/13 19:15 [pubmed]
PHST- 2023/07/13 15:18 [entrez]
PHST- 2023/07/11 00:00 [pmc-release]
AID - d3ra03080f [pii]
AID - 10.1039/d3ra03080f [doi]
PST - epublish
SO  - RSC Adv. 2023 Jul 11;13(30):20830-20838. doi: 10.1039/d3ra03080f. eCollection 
      2023 Jul 7.