PMID- 37441953
OWN - NLM
STAT- MEDLINE
DCOM- 20230920
LR  - 20230920
IS  - 1090-2414 (Electronic)
IS  - 0147-6513 (Linking)
VI  - 263
DP  - 2023 Sep 15
TI  - Pesticides residues determination and probabilistic health risk assessment in the 
      soil and cantaloupe by Monte Carlo simulation: A case study in Kashan and 
      Aran-Bidgol, Iran.
PG  - 115229
LID - S0147-6513(23)00733-9 [pii]
LID - 10.1016/j.ecoenv.2023.115229 [doi]
AB  - Cantaloupe is a popular agricultural product in the hot season of Iran. On the 
      other hand, the frequent use of pesticides in cantaloupe fields is the most 
      important threat to the health of farmers and consumers. Therefore, the present 
      study aims to measure the concentration of diazinon (DZN), chlorpyrifos (CPF), 
      and malathion (MLT) in cantaloupe cultivated in Kashan and Aran-Bidgol (Iran) and 
      to estimate the possible oral and dermal risk of these pesticides by Monte Carlo 
      simulation (MCS). 36 cantaloupe samples, 18 samples before, and 18 samples after 
      the latent period were collected from different places of cantaloupe cultivation 
      from April to May 2021. After measuring the pesticides using the QuEChERS 
      approach, oral and dermal risk assessments were calculated.The mean and standard 
      deviation of the concentrations of chlorpyrifos, malathion, and diazinon in 18 
      cantaloupe samples, after the latent period, were (30.39 +/- 13.85), 
      (18.361 +/- 1.8), and (21.97 +/- 0.86) mug kg-(1), respectively. Concentration of 
      Malathion, diazinon, and Chlorpyrifos in the soil were 0.22, 0.25, and 
      0.3 mg kg-(1), respectively, and pesticide cumulative risk assessment in soil was 
      obtained 0.011 for Malathion, 0.05 for diazinon and 0.03 for Chlorpyrifos. Target 
      Hazard Quotient (THQ) according to the cantaloupe consumption and dermal exposure 
      in children and adults, was safe range. Although non-cancerous dermal and oral 
      risk of cantaloupe is low, constant exposure can be harmful. Therefore, the 
      findings of this study play an important role in increasing the understanding of 
      the negative health consequences of pesticide contamination in cantaloupe for 
      consumers, especially local residents, and can help by adopting remedial 
      strategies to reduce environmental concerns.
CI  - Copyright (c) 2023 The Authors. Published by Elsevier Inc. All rights reserved.
FAU - Hesami Arani, Mohsen
AU  - Hesami Arani M
AD  - Department of Environmental Health Engineering, School of public Health, Iran 
      University of Medical Sciences, Tehran, Iran; Health System Research, Deputy of 
      Health, Kashan University of Medical Sciences, Kashan, Iran.
FAU - Kermani, Majid
AU  - Kermani M
AD  - Department of Environmental Health Engineering, School of public Health, Iran 
      University of Medical Sciences, Tehran, Iran; Research Center for Environmental 
      Health Technology, Iran University of Medical Sciences, Tehran, Iran.
FAU - Rezaei Kalantary, Roshanak
AU  - Rezaei Kalantary R
AD  - Department of Environmental Health Engineering, School of public Health, Iran 
      University of Medical Sciences, Tehran, Iran; Research Center for Environmental 
      Health Technology, Iran University of Medical Sciences, Tehran, Iran. Electronic 
      address: rezaei.r@iums.ac.ir.
FAU - Jaafarzadeh, Neamatollah
AU  - Jaafarzadeh N
AD  - Environmental Technologies Research Center, Ahvaz Jundishapur University of 
      Medical Sciences, Ahvaz, Iran. Electronic address: n.jaafarzade@gmail.com.
FAU - Bagheri Arani, Samaneh
AU  - Bagheri Arani S
AD  - Advanced studies of Art, Faculty of Art and Architecture, University of Kashan, 
      Kashan, Iran.
LA  - eng
PT  - Journal Article
DEP - 20230711
PL  - Netherlands
TA  - Ecotoxicol Environ Saf
JT  - Ecotoxicology and environmental safety
JID - 7805381
RN  - 0 (Pesticide Residues)
RN  - JCS58I644W (Chlorpyrifos)
RN  - YUS1M1Q929 (Diazinon)
RN  - U5N7SU872W (Malathion)
RN  - 0 (Soil)
RN  - 0 (Pesticides)
SB  - IM
MH  - Adult
MH  - Child
MH  - Humans
MH  - *Pesticide Residues/analysis
MH  - *Chlorpyrifos/analysis
MH  - Diazinon
MH  - Malathion
MH  - *Cucumis melo
MH  - Soil
MH  - Iran
MH  - Monte Carlo Method
MH  - *Pesticides/analysis
MH  - Risk Assessment
OTO - NOTNLM
OT  - Cantaloupe
OT  - Chlorpyrifos
OT  - Diazinon
OT  - Malathion
OT  - Monte Carlo Simulation
OT  - Risk Assessments
OT  - Soil
COIS- Declaration of Competing Interest The authors of this article declare that they 
      have no conflict of interests.
EDAT- 2023/07/14 13:07
MHDA- 2023/09/20 06:42
CRDT- 2023/07/13 18:07
PHST- 2023/04/13 00:00 [received]
PHST- 2023/06/11 00:00 [revised]
PHST- 2023/07/01 00:00 [accepted]
PHST- 2023/09/20 06:42 [medline]
PHST- 2023/07/14 13:07 [pubmed]
PHST- 2023/07/13 18:07 [entrez]
AID - S0147-6513(23)00733-9 [pii]
AID - 10.1016/j.ecoenv.2023.115229 [doi]
PST - ppublish
SO  - Ecotoxicol Environ Saf. 2023 Sep 15;263:115229. doi: 
      10.1016/j.ecoenv.2023.115229. Epub 2023 Jul 11.