PMID- 37443053
OWN - NLM
STAT- MEDLINE
DCOM- 20230717
LR  - 20230718
IS  - 1477-7525 (Electronic)
IS  - 1477-7525 (Linking)
VI  - 21
IP  - 1
DP  - 2023 Jul 13
TI  - Health-related quality of life and its associated factors among outpatients with 
      heart failure: a cross-sectional study.
PG  - 73
LID - 10.1186/s12955-023-02142-w [doi]
LID - 73
AB  - BACKGROUND: Heart Failure (HF) is a chronic disease associated with life-limiting 
      symptoms that could negatively impact patients' health-related quality of life 
      (HRQOL). This study aimed to evaluate HRQOL and explore the factors associated 
      with poor HRQOL among patients with HF in Jordan. METHODS: This cross-sectional 
      study used the validated Arabic version of the Minnesota Living with Heart 
      Failure Questionnaire to assess HRQOL in outpatients with HF visiting cardiology 
      clinics at two public hospitals in Jordan. Variables were collected from medical 
      records and custom-designed questionnaires, including socio-demographics, 
      biomedical variables, and disease and medication characteristics. Ordinal 
      regression analysis was used to explore variables associated with poor HRQOL 
      among HF patients. RESULTS: Ordinal regression analysis showed that the number of 
      HF medications (P < 0.05) and not taking a loop diuretic (P < 0.05) significantly 
      increased HRQOL, while the number of other chronic diseases (P < 0.05), stage 
      III/IV of HF (P < 0.01), low monthly income (P < 0.05), and being unsatisfied 
      with the prescribed medications (P < 0.05) significantly decreased HRQOL of HF 
      patients. CONCLUSIONS: Although the current study demonstrated low HRQOL among 
      patients with HF in Jordan, HRQOL has a considerable opportunity for improvement 
      in those patients. Variables identified in the present study, including low 
      monthly income, higher New York Heart Association (NYHA) classes, a higher number 
      of comorbidities, and/or taking a loop diuretic, should be considered in future 
      intervention programs, aiming to improve HRQOL in patients with HF.
CI  - (c) 2023. The Author(s).
FAU - Jarab, Anan S
AU  - Jarab AS
AD  - Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of 
      Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan.
AD  - College of Pharmacy, Al Ain University, Abu Dhabi, UAE.
FAU - Hamam, Hanan W
AU  - Hamam HW
AD  - Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of 
      Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan.
FAU - Al-Qerem, Walid A
AU  - Al-Qerem WA
AD  - Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, 
      P.O. Box 130, Amman, 11733, Jordan.
FAU - Heshmeh, Shrouq R Abu
AU  - Heshmeh SRA
AD  - Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of 
      Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan.
FAU - Mukattash, Tareq L
AU  - Mukattash TL
AD  - Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of 
      Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan.
FAU - Alefishat, Eman A
AU  - Alefishat EA
AUID- ORCID: 0000-0003-4584-9166
AD  - Department of Pharmacology, College of Medicine and Health Science, Khalifa 
      University of Science and Technology, Abu Dhabi, 127788, United Arab Emirates. 
      eman.alefishat@ku.ac.ae.
AD  - Department of Biopharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, The 
      University of Jordan, Amman, 11942, Jordan. eman.alefishat@ku.ac.ae.
AD  - Center For Biotechnology, Khalifa University of Science and Technology, Abu 
      Dhabi, 127788, United Arab Emirates. eman.alefishat@ku.ac.ae.
LA  - eng
PT  - Journal Article
DEP - 20230713
PL  - England
TA  - Health Qual Life Outcomes
JT  - Health and quality of life outcomes
JID - 101153626
RN  - 0 (Sodium Potassium Chloride Symporter Inhibitors)
SB  - IM
MH  - Humans
MH  - *Quality of Life
MH  - Cross-Sectional Studies
MH  - Outpatients
MH  - Sodium Potassium Chloride Symporter Inhibitors
MH  - *Heart Failure/complications
MH  - Surveys and Questionnaires
MH  - Chronic Disease
PMC - PMC10347808
OTO - NOTNLM
OT  - Health-related quality of life
OT  - Heart failure
OT  - Intervention
OT  - Jordan
OT  - Minnesota living with heart failure questionnaire
COIS- The authors declare no competing interests.
EDAT- 2023/07/14 13:05
MHDA- 2023/07/17 06:42
PMCR- 2023/07/13
CRDT- 2023/07/13 23:30
PHST- 2022/11/22 00:00 [received]
PHST- 2023/06/03 00:00 [accepted]
PHST- 2023/07/17 06:42 [medline]
PHST- 2023/07/14 13:05 [pubmed]
PHST- 2023/07/13 23:30 [entrez]
PHST- 2023/07/13 00:00 [pmc-release]
AID - 10.1186/s12955-023-02142-w [pii]
AID - 2142 [pii]
AID - 10.1186/s12955-023-02142-w [doi]
PST - epublish
SO  - Health Qual Life Outcomes. 2023 Jul 13;21(1):73. doi: 10.1186/s12955-023-02142-w.