PMID- 37445446
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230718
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 12
IP  - 13
DP  - 2023 Jun 30
TI  - Patient-Reported Outcome Measures following Coblation Nucleoplasty for Cervical 
      Discogenic Dizziness.
LID - 10.3390/jcm12134413 [doi]
LID - 4413
AB  - BACKGROUND: There is little research in the literature comparing the efficacy of 
      coblation nucleoplasty with conservative treatment in the treatment of cervical 
      discogenic dizziness and reporting the achieved rate of minimal clinically 
      important differences (MCID) and patient acceptable symptom state (PASS) after 
      surgery. This retrospective study aims to explore the patient-reported outcome 
      measures (PROM) following coblation nucleoplasty for cervical discogenic 
      dizziness and to compare the therapeutic effect of coblation nucleoplasty with 
      prolonged conservative treatment. METHODS: Sixty-one patients with cervical 
      discogenic dizziness and a positive intradiscal diagnostic test eligible for 
      single-level cervical coblation nucleoplasty were included in the study. Among 
      these 61 patients, 40 patients underwent cervical coblation nucleoplasty, while 
      the remaining 21 patients refused surgery and received continued conservative 
      treatment. The primary PROMs were the intensity and frequency of dizziness and 
      secondary PROMs were related to the neck disability index (NDI) and visual analog 
      scale (VAS) for neck pain (VAS-neck) during a 12-month follow-up period. 
      Moreover, the achieved rate of MCID and PASS in both groups was assessed 12 
      months after surgery. RESULTS: Dizziness intensity, dizziness frequency, VAS-neck 
      score, and NDI score were significantly improved from the baseline at all 
      follow-up time points in both treatment groups, except for showing no significant 
      improvement in dizziness frequency in the conservative treatment group at 6 and 
      12 months after surgery. However, at each follow-up time point, the above indexes 
      were lower in the surgery group than in the conservative treatment group. In 
      addition, the achieved rates for PASS and MCID in all indexes in the surgery 
      group were significantly higher than those in the conservative treatment group at 
      12 months after surgery. CONCLUSIONS: Cervical coblation nucleoplasty 
      significantly improved the intensity and frequency of dizziness, neck pain, and 
      NDI in patients with cervical discogenic dizziness, and the results were superior 
      to those from prolonged conservative treatment. Meanwhile, cervical coblation 
      nucleoplasty is a good choice for patients with chronic neck pain and refractory 
      cervical discogenic dizziness who have not demonstrated the indications for open 
      surgery and have not responded well to conservative treatment.
FAU - Li, Yongchao
AU  - Li Y
AUID- ORCID: 0000-0002-4460-9702
AD  - Department of Orthopedics, The Third Medical Centre of Chinese PLA General 
      Hospital, Beijing 100039, China.
FAU - Wu, Bing
AU  - Wu B
AD  - Department of Orthopedics, The Third Medical Centre of Chinese PLA General 
      Hospital, Beijing 100039, China.
FAU - Li, Mao
AU  - Li M
AD  - Department of Surgery, Peking University Hospital, Beijing 100034, China.
FAU - Pang, Xiaodong
AU  - Pang X
AD  - Department of Orthopedics, The Third Medical Centre of Chinese PLA General 
      Hospital, Beijing 100039, China.
FAU - Yang, Liang
AU  - Yang L
AD  - Department of Orthopeadics, Featured Medical Center of Chinese People's Armed 
      Police Forces, Tianjin 300162, China.
FAU - Dai, Chen
AU  - Dai C
AD  - Department of Orthopedics, The Third Medical Centre of Chinese PLA General 
      Hospital, Beijing 100039, China.
FAU - Peng, Baogan
AU  - Peng B
AD  - Department of Orthopedics, The Third Medical Centre of Chinese PLA General 
      Hospital, Beijing 100039, China.
LA  - eng
PT  - Journal Article
DEP - 20230630
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC10342256
OTO - NOTNLM
OT  - cervical discogenic dizziness
OT  - cervicogenic dizziness
OT  - coblation nucleoplasty
OT  - neck pain
OT  - patient-reported outcome measures
COIS- The authors declare no conflict of interest.
EDAT- 2023/07/14 13:06
MHDA- 2023/07/14 13:07
PMCR- 2023/06/30
CRDT- 2023/07/14 01:11
PHST- 2023/05/15 00:00 [received]
PHST- 2023/06/25 00:00 [revised]
PHST- 2023/06/28 00:00 [accepted]
PHST- 2023/07/14 13:07 [medline]
PHST- 2023/07/14 13:06 [pubmed]
PHST- 2023/07/14 01:11 [entrez]
PHST- 2023/06/30 00:00 [pmc-release]
AID - jcm12134413 [pii]
AID - jcm-12-04413 [pii]
AID - 10.3390/jcm12134413 [doi]
PST - epublish
SO  - J Clin Med. 2023 Jun 30;12(13):4413. doi: 10.3390/jcm12134413.