PMID- 37447320
OWN - NLM
STAT- MEDLINE
DCOM- 20230717
LR  - 20230718
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 15
IP  - 13
DP  - 2023 Jun 30
TI  - Binge-Eating Precursors in Children and Adolescents: Neurodevelopment, and the 
      Potential Contribution of Ultra-Processed Foods.
LID - 10.3390/nu15132994 [doi]
LID - 2994
AB  - Binge-eating disorder (BED) is a highly prevalent disorder. Subthreshold BED 
      conditions (sBED) are even more frequent in youth, but their significance 
      regarding BED etiology and long-term prognosis is unclear. A better understanding 
      of brain findings associated with BED and sBED, in the context of critical 
      periods for neurodevelopment, is relevant to answer such questions. The present 
      narrative review starts from the knowledge of the development of emotional 
      self-regulation in youth, and the brain circuits supporting emotion-regulation 
      and eating behaviour. Next, neuroimaging studies with sBED and BED samples will 
      be reviewed, and their brain-circuitry overlap will be examined. Deficits in 
      inhibition control systems are observed to precede, and hyperactivity of reward 
      regions to characterize, sBED, with overlapping findings in BED. The imbalance 
      between reward/inhibition systems, and the implication of 
      interoception/homeostatic processing brain systems should be further examined. 
      Recent knowledge of the potential impact that the high consumption of 
      ultra-processed foods in paediatric samples may have on these sBED/BED-associated 
      brain systems is then discussed. There is a need to identify, early on, those 
      sBED individuals at risk of developing BED at neurodevelopmental stages when 
      there is a great possibility of prevention. However, more neuroimaging studies 
      with sBED/BED pediatric samples are needed.
FAU - Via, Esther
AU  - Via E
AUID- ORCID: 0000-0002-2331-3232
AD  - Child and Adolescent Mental Health Research Group, Institut de Recerca Sant Joan 
      de Deu, Santa Rosa 39-57, 08950 Esplugues de Llobregat, Spain.
AD  - Department of Child and Adolescent Mental Health, Hospital Sant Joan de Deu, 
      Passeig Sant Joan de Deu, 2, 08950 Esplugues de Llobregat, Spain.
FAU - Contreras-Rodriguez, Oren
AU  - Contreras-Rodriguez O
AUID- ORCID: 0000-0001-8922-8084
AD  - Medical Imaging, Girona Biomedical Research Institute (IdIBGi), Parc Hospitalari 
      Marti i Julia-Edifici M2, Salt, 17190 Girona, Spain.
AD  - Health Institute Carlos III (ISCIII) and CIBERSAM, 28029 Madrid, Spain.
AD  - Department of Psychiatry and Legal Medicine, Faculty of Medicine, Universitat 
      Autonoma de Barcelona, 08193 Bellaterra, Spain.
LA  - eng
GR  - PI22/00655/Instituto de Salud Carlos III/
GR  - PI22/00645/Instituto de Salud Carlos III/
GR  - proyectos intramurales/Centro de Investigacion Biomedica en Red de Salud Mental/
GR  - Miguel Servet (CP20/00165)/Instituto de Salud Carlos III/
PT  - Journal Article
PT  - Review
DEP - 20230630
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
SB  - IM
MH  - Humans
MH  - Adolescent
MH  - Child
MH  - *Binge-Eating Disorder/psychology
MH  - Food, Processed
MH  - *Bulimia/complications
MH  - Brain/diagnostic imaging
MH  - Neuroimaging
PMC - PMC10347198
OTO - NOTNLM
OT  - MRI
OT  - adolescents
OT  - binge eating
OT  - children
OT  - emotional eating
OT  - inhibition
OT  - reward
OT  - ultra-processed food
COIS- The authors declare no conflict of interest.
EDAT- 2023/07/14 13:06
MHDA- 2023/07/17 06:42
PMCR- 2023/06/30
CRDT- 2023/07/14 01:22
PHST- 2023/05/08 00:00 [received]
PHST- 2023/06/12 00:00 [revised]
PHST- 2023/06/28 00:00 [accepted]
PHST- 2023/07/17 06:42 [medline]
PHST- 2023/07/14 13:06 [pubmed]
PHST- 2023/07/14 01:22 [entrez]
PHST- 2023/06/30 00:00 [pmc-release]
AID - nu15132994 [pii]
AID - nutrients-15-02994 [pii]
AID - 10.3390/nu15132994 [doi]
PST - epublish
SO  - Nutrients. 2023 Jun 30;15(13):2994. doi: 10.3390/nu15132994.