PMID- 37448444 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230718 IS - 1831-4732 (Electronic) IS - 1831-4732 (Linking) VI - 21 IP - 7 DP - 2023 Jul TI - Modification of the existing maximum residue levels and setting of import tolerances for flupyradifurone and DFA in various crops and animal commodities. PG - e08081 LID - 10.2903/j.efsa.2023.8081 [doi] LID - e08081 AB - In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant Bayer CropScience SA-NV submitted a request to the competent national authority in the Netherlands to modify the existing maximum residue levels (MRLs) and to set import tolerances for the active substance flupyradifurone and its metabolite difluoroacetic acid (DFA) in various plant and animal commodities. The data submitted in support of the requests were found sufficient to derive MRL proposals for flupyradifurone and/or DFA in the crops under consideration. The calculated EU livestock dietary burden indicated that for several animal matrices the EU MRLs for flupyradifurone and/or DFA would need to be modified. Adequate analytical methods for enforcement are available to control the residues of both compounds in the plant and animal commodities under consideration, and in honey. Based on the risk assessment results, EFSA concluded that the proposed and authorised uses of flupyradifurone on various crops and subsequent residues of flupyradifurone and DFA in plant and animal commodities will not result in a consumer exposure exceeding the toxicological reference values and therefore is unlikely to pose a risk to consumers' health. CI - (c) 2023 European Food Safety Authority. EFSA Journal published by Wiley-VCH GmbH on behalf of European Food Safety Authority. CN - EFSA (European Food Safety Authority) FAU - Bellisai, Giulia AU - Bellisai G FAU - Bernasconi, Giovanni AU - Bernasconi G FAU - Carrasco Cabrera, Luis AU - Carrasco Cabrera L FAU - Castellan, Irene AU - Castellan I FAU - Del Aguila, Monica AU - Del Aguila M FAU - Ferreira, Lucien AU - Ferreira L FAU - Santonja, German Giner AU - Santonja GG FAU - Greco, Luna AU - Greco L FAU - Jarrah, Samira AU - Jarrah S FAU - Leuschner, Renata AU - Leuschner R FAU - Miron, Ileana AU - Miron I FAU - Nave, Stefanie AU - Nave S FAU - Pedersen, Ragnor AU - Pedersen R FAU - Reich, Hermine AU - Reich H FAU - Ruocco, Silvia AU - Ruocco S FAU - Santos, Miguel AU - Santos M FAU - Scarlato, Alessia Pia AU - Scarlato AP FAU - Theobald, Anne AU - Theobald A FAU - Tiramani, Manuela AU - Tiramani M FAU - Verani, Alessia AU - Verani A LA - eng PT - Journal Article DEP - 20230712 PL - United States TA - EFSA J JT - EFSA journal. European Food Safety Authority JID - 101642076 PMC - PMC10336656 OTO - NOTNLM OT - MRL OT - animal commodities OT - consumer risk assessment OT - difluoroacetic acid (DFA) OT - flupyradifurone OT - pesticide OT - various crops EDAT- 2023/07/14 13:07 MHDA- 2023/07/14 13:08 PMCR- 2023/07/12 CRDT- 2023/07/14 03:44 PHST- 2023/07/14 13:08 [medline] PHST- 2023/07/14 13:07 [pubmed] PHST- 2023/07/14 03:44 [entrez] PHST- 2023/07/12 00:00 [pmc-release] AID - EFS28081 [pii] AID - 10.2903/j.efsa.2023.8081 [doi] PST - epublish SO - EFSA J. 2023 Jul 12;21(7):e08081. doi: 10.2903/j.efsa.2023.8081. eCollection 2023 Jul.