PMID- 37449451
OWN - NLM
STAT- MEDLINE
DCOM- 20230912
LR  - 20230912
IS  - 1522-726X (Electronic)
IS  - 1522-1946 (Linking)
VI  - 102
IP  - 3
DP  - 2023 Sep
TI  - Correlation between measured and predicted mismatch with valve hemodynamics in 
      transcatheter aortic valve replacement: A sex-based analysis.
PG  - 505-512
LID - 10.1002/ccd.30764 [doi]
AB  - BACKGROUND: Data regarding the reliability of predicted effective orifice area 
      indexed (pEOAi) is scarce in transcatheter aortic valve replacement (TAVR). AIMS: 
      To assess the validity of the pEOAi in TAVR by correlating its value with 
      echocardiography-derived hemodynamic data. METHODS: A single-center retrospective 
      cohort study of TAVR patients from 2012 to 2021 with available echocardiograms 
      was conducted. Patient-prosthesis mismatch (PPM) was defined based on the Valve 
      Academic Research Consortium 3 criteria. The main endpoints were the congruence 
      of measured effective orifice area indexed (EOAi) and pEOAi with the hemodynamic 
      data obtained by echocardiography. The secondary endpoint included a correlation 
      of predicted PPM (pPPM) and measured PPM (mPPM) with postoperative New York Heart 
      Association (NYHA) status. RESULTS: A total of 318 patients were included. pPPM 
      was more frequent than mPPM (54 [17%]; all moderate PPM vs. 39 [12.3%]: 32 
      moderate and 7 severe PPM). Predicted and measured EOAi were statistically 
      correlated with postprocedural transvalvular mean gradient and Doppler velocity 
      index (all p < 0.001), including in both sex-based subgroups. The positive 
      predictive value and negative predictive value (NPV) of pPPM for postprocedural 
      transvalvular mean gradient >/= 20 mmHg were 16% and 97%, respectively. Only pPPM 
      was significantly more prevalent in the group in which NYHA failed to improve 
      than in those with symptom improvement (30.1% vs. 16%, p = 0.027). CONCLUSION: 
      Predicted PPM has an excellent NPV for postprocedural transvalvular mean 
      gradient >/= 20 mmHg and seems to be a good predictor of NYHA status evolution as 
      opposed to measured PPM. Predicted EOAi can be used in procedural planning to 
      reduce the risk of PPM in both TAVR male and female patients.
CI  - (c) 2023 Wiley Periodicals LLC.
FAU - Natalis, Alexandre
AU  - Natalis A
AUID- ORCID: 0000-0002-9146-0146
AD  - Centre Hospitalier Universitaire de Montreal (CHUM), Montreal, Quebec, Canada.
FAU - Masson, Jean-Bernard
AU  - Masson JB
AD  - Centre Hospitalier Universitaire de Montreal (CHUM), Montreal, Quebec, Canada.
FAU - Mansour, Mohamad J
AU  - Mansour MJ
AUID- ORCID: 0000-0003-4184-275X
AD  - Centre Hospitalier Universitaire de Montreal (CHUM), Montreal, Quebec, Canada.
FAU - Asmar, Mike Al
AU  - Asmar MA
AD  - Centre Hospitalier Universitaire de Montreal (CHUM), Montreal, Quebec, Canada.
FAU - Potvin, Jeannot
AU  - Potvin J
AD  - Centre Hospitalier Universitaire de Montreal (CHUM), Montreal, Quebec, Canada.
FAU - Gobeil, Jean-Francois
AU  - Gobeil JF
AD  - Centre Hospitalier Universitaire de Montreal (CHUM), Montreal, Quebec, Canada.
FAU - Riahi, Mounir
AU  - Riahi M
AUID- ORCID: 0000-0002-6770-2651
AD  - Centre Hospitalier Universitaire de Montreal (CHUM), Montreal, Quebec, Canada.
FAU - Noiseux, Nicolas
AU  - Noiseux N
AD  - Centre Hospitalier Universitaire de Montreal (CHUM), Montreal, Quebec, Canada.
FAU - Stevens, Louis-Mathieu
AU  - Stevens LM
AD  - Centre Hospitalier Universitaire de Montreal (CHUM), Montreal, Quebec, Canada.
FAU - Forcillo, Jessica
AU  - Forcillo J
AD  - Centre Hospitalier Universitaire de Montreal (CHUM), Montreal, Quebec, Canada.
LA  - eng
PT  - Journal Article
DEP - 20230714
PL  - United States
TA  - Catheter Cardiovasc Interv
JT  - Catheterization and cardiovascular interventions : official journal of the 
      Society for Cardiac Angiography & Interventions
JID - 100884139
SB  - IM
MH  - Humans
MH  - Male
MH  - Female
MH  - *Transcatheter Aortic Valve Replacement/adverse effects
MH  - Aortic Valve/diagnostic imaging/surgery
MH  - *Heart Valve Prosthesis Implantation/adverse effects
MH  - *Heart Valve Prosthesis/adverse effects
MH  - *Aortic Valve Stenosis/diagnostic imaging/surgery/etiology
MH  - Retrospective Studies
MH  - Reproducibility of Results
MH  - Treatment Outcome
MH  - Hemodynamics
MH  - Prosthesis Design
OTO - NOTNLM
OT  - aortic stenosis
OT  - gender issue
OT  - hemodynamics
OT  - imaging modalities
OT  - patient-prosthesis mismatch
OT  - transcatheter aortic valve replacement
EDAT- 2023/07/14 13:08
MHDA- 2023/09/12 06:41
CRDT- 2023/07/14 05:29
PHST- 2023/05/15 00:00 [revised]
PHST- 2023/01/15 00:00 [received]
PHST- 2023/07/08 00:00 [accepted]
PHST- 2023/09/12 06:41 [medline]
PHST- 2023/07/14 13:08 [pubmed]
PHST- 2023/07/14 05:29 [entrez]
AID - 10.1002/ccd.30764 [doi]
PST - ppublish
SO  - Catheter Cardiovasc Interv. 2023 Sep;102(3):505-512. doi: 10.1002/ccd.30764. Epub 
      2023 Jul 14.