PMID- 37451007 OWN - NLM STAT- MEDLINE DCOM- 20230808 LR - 20230808 IS - 1873-2828 (Electronic) IS - 1350-4177 (Print) IS - 1350-4177 (Linking) VI - 98 DP - 2023 Aug TI - Acoustic cavitation for the process intensification of biological oxidation of CETP effluent containing mainly pharmaceutical compounds: Understanding into effect of parameters and toxicity analysis. PG - 106524 LID - S1350-4177(23)00236-5 [pii] LID - 10.1016/j.ultsonch.2023.106524 [doi] LID - 106524 AB - The current work investigates the efficacy of acoustic cavitation (AC) based pretreatment as a process intensification method for improving the conventional biological oxidation (BO) treatment of the effluent from common effluent treatment plant (CETP) mainly containing pharmaceutical compounds. The effluent acclimatized with cow dung-based sludge was utilized for the aerobic oxidation with an optimum condition of 1:3 ratio of sludge to effluent and 6 h as duration. COD reduction of 19.58% was achieved with the conventional biological oxidation, which was demonstrated to be improved by incorporating acoustic cavitation-based pretreatment approaches under optimized conditions of 125 W and 70% duty cycle for only AC as well as oxidant loadings as 1000 mg/L for H(2)O(2), 250 mg/L Fe(II) with 1000 mg/L H(2)O(2) for Fenton, 1000 mg/L for KPS and 0.5 L/min for the O(3) during the combination approaches. The improved COD reduction after the use of pretreatment approaches followed by the BO of 6 h duration was 29.26%, 72.42%, 85.47%, 45.68% and 69.26% for the AC, AC + H(2)O(2), AC + Fenton, AC + KPS and AC + O(3) based approaches respectively. The toxicity assay of the effluent before and after every pretreatment approach using bacterial strains ofStaphylococcus aureusandPseudomonas aeruginosaensured the biodegradability of the treated effluent as no toxic intermediates could be seen. Overall, the present work elucidated the effectiveness of acoustic cavitation-based pretreatment approaches for the improvement of conventional BO of CETP effluent. CI - Copyright (c) 2023 The Author(s). Published by Elsevier B.V. All rights reserved. FAU - Lakshmi, N J AU - Lakshmi NJ AD - Department of Chemical Engineering, Institute of Chemical Technology, Matunga, Mumbai 400019, India. FAU - Gogate, Parag R AU - Gogate PR AD - Department of Chemical Engineering, Institute of Chemical Technology, Matunga, Mumbai 400019, India. Electronic address: pr.gogate@ictmumbai.edu.in. FAU - Pandit, Aniruddha B AU - Pandit AB AD - Department of Chemical Engineering, Institute of Chemical Technology, Matunga, Mumbai 400019, India. LA - eng PT - Journal Article DEP - 20230710 PL - Netherlands TA - Ultrason Sonochem JT - Ultrasonics sonochemistry JID - 9433356 RN - 0 (Sewage) RN - BBX060AN9V (Hydrogen Peroxide) RN - 0 (Pharmaceutical Preparations) RN - 0 (Water Pollutants, Chemical) SB - IM MH - *Sewage/microbiology MH - Waste Disposal, Fluid/methods MH - Hydrogen Peroxide MH - Oxidation-Reduction MH - Acoustics MH - Pharmaceutical Preparations MH - *Water Pollutants, Chemical PMC - PMC10368907 OTO - NOTNLM OT - Acclimatized sludge OT - Acoustic Cavitation OT - Biological oxidation OT - Common Effluent Treatment Plant OT - Process intensification COIS- Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2023/07/15 10:42 MHDA- 2023/08/08 06:42 PMCR- 2023/07/10 CRDT- 2023/07/14 18:02 PHST- 2023/04/16 00:00 [received] PHST- 2023/06/20 00:00 [revised] PHST- 2023/07/09 00:00 [accepted] PHST- 2023/08/08 06:42 [medline] PHST- 2023/07/15 10:42 [pubmed] PHST- 2023/07/14 18:02 [entrez] PHST- 2023/07/10 00:00 [pmc-release] AID - S1350-4177(23)00236-5 [pii] AID - 106524 [pii] AID - 10.1016/j.ultsonch.2023.106524 [doi] PST - ppublish SO - Ultrason Sonochem. 2023 Aug;98:106524. doi: 10.1016/j.ultsonch.2023.106524. Epub 2023 Jul 10.