PMID- 37453910
OWN - NLM
STAT- MEDLINE
DCOM- 20230731
LR  - 20230802
IS  - 1879-291X (Electronic)
IS  - 0301-5629 (Linking)
VI  - 49
IP  - 9
DP  - 2023 Sep
TI  - Reliability of Ultrasound Imaging in Examining Integrity and Inflammation in the 
      Dorsalis Pedis Artery.
PG  - 2199-2202
LID - S0301-5629(23)00211-9 [pii]
LID - 10.1016/j.ultrasmedbio.2023.06.017 [doi]
AB  - OBJECTIVE: Assessment of small vessel inflammatory diseases such as rheumatoid 
      vasculitis is challenging. Small arteries such as the dorsalis pedis artery (DPA) 
      are difficult to assess for changes in the arterial wall with medical imaging. 
      Ultrasound imaging is a viable tool for examining the integrity and inflammatory 
      changes in the arterial wall; however, no empirical data on its reliability have 
      been described. METHODS: We measured the intra- and inter-rater reliability of 
      ultrasound measurements across five parameters evaluating arterial integrity of 
      the proximal DPA in participants with and without small vessel disease. We 
      recruited 10 participants with rheumatoid arthritis and 10 healthy controls. Two 
      sonographers using ultrasound independently measured DPA lumen diameter, artery 
      diameter, lumen-to-arterial diameter ratio, arterial Doppler velocity and 
      inflammatory changes in the proximal wall of the DPA. The intraclass correlation 
      coefficient (ICC) was used to evaluate 95% confidence intervals within and 
      between raters. Bland-Altman analyses were used to assess limits of agreement and 
      were compared with minimal clinically important differences (MCID). RESULTS: Four 
      of five selected parameters were found to have excellent intra- and inter-rater 
      reliability within and between raters (ICC = 0.903-0.996). Acceptable reliability 
      was found for measurement of arterial blood flow velocity within raters 
      (ICC = 0.815-0.909), but not between raters (ICC = 0.634). Standard mean errors 
      in all parameters were within minimal clinically important differences. 
      CONCLUSION: Ultrasound imaging has been found to be a reliable method of 
      assessment of arterial integrity and inflammation of the proximal DPA in people 
      with small vessel disease. Evaluation of arterial blood flow velocity requires 
      cautious interpretation.
CI  - Copyright (c) 2023 World Federation for Ultrasound in Medicine & Biology. Published 
      by Elsevier Inc. All rights reserved.
FAU - Boman, Robyn
AU  - Boman R
AD  - School of Health Sciences, Western Sydney University, NSW, Australia.
FAU - Penkala, Stefania
AU  - Penkala S
AD  - School of Health Sciences, Western Sydney University, NSW, Australia; 
      Translational Health Research Institute, Western Sydney University, NSW, 
      Australia.
FAU - Chan, Rosa H M
AU  - Chan RHM
AD  - Department of Electrical Engineering, City University of Hong Kong, Hong Kong.
FAU - Joshua, Fredrick
AU  - Joshua F
AD  - Faculty of Medicine and Health Sciences, Macquarie University, NSW, Australia.
FAU - Cheung, Roy T H
AU  - Cheung RTH
AD  - School of Health Sciences, Western Sydney University, NSW, Australia; 
      Translational Health Research Institute, Western Sydney University, NSW, 
      Australia. Electronic address: Roy.Cheung@westernsydney.edu.au.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230713
PL  - England
TA  - Ultrasound Med Biol
JT  - Ultrasound in medicine & biology
JID - 0410553
SB  - IM
MH  - Humans
MH  - Reproducibility of Results
MH  - Ultrasonography/methods
MH  - *Ultrasonography, Doppler
MH  - Arteries
MH  - *Vascular Diseases
MH  - Inflammation/diagnostic imaging
OTO - NOTNLM
OT  - Autoimmune disease
OT  - Blood vessel
OT  - Measurement agreement
COIS- Conflict of interest The authors declare no competing interests.
EDAT- 2023/07/16 01:07
MHDA- 2023/07/31 06:43
CRDT- 2023/07/15 22:02
PHST- 2023/05/11 00:00 [received]
PHST- 2023/06/06 00:00 [revised]
PHST- 2023/06/26 00:00 [accepted]
PHST- 2023/07/31 06:43 [medline]
PHST- 2023/07/16 01:07 [pubmed]
PHST- 2023/07/15 22:02 [entrez]
AID - S0301-5629(23)00211-9 [pii]
AID - 10.1016/j.ultrasmedbio.2023.06.017 [doi]
PST - ppublish
SO  - Ultrasound Med Biol. 2023 Sep;49(9):2199-2202. doi: 
      10.1016/j.ultrasmedbio.2023.06.017. Epub 2023 Jul 13.