PMID- 37454826
OWN - NLM
STAT- MEDLINE
DCOM- 20231216
LR  - 20231216
IS  - 1535-6280 (Electronic)
IS  - 0146-2806 (Linking)
VI  - 49
IP  - 1 Pt A
DP  - 2024 Jan
TI  - Functional and Quality of Life Outcomes After TAVR in Patients With Low Gradient 
      Aortic Stenosis.
PG  - 101941
LID - S0146-2806(23)00358-4 [pii]
LID - 10.1016/j.cpcardiol.2023.101941 [doi]
AB  - Severe aortic stenosis is a common valvular heart disease associated with 
      significant mortality and morbidity. Transcatheter aortic valve replacement 
      (TAVR) is an effective treatment for this condition. Less data is available 
      regarding functional and quality-of-life outcomes in patients with severe, 
      low-gradient aortic stenosis following TAVR. This single-center, retrospective 
      study compared changes in New York Heart Association (NYHA) class and Kansas City 
      Cardiomyopathy Questionnaire (KCCQ) scores at 30 days and 1 year in patients with 
      3 variants of severe, low-gradient aortic stenosis following TAVR. Secondary 
      outcomes included 1-year major adverse cardiovascular event. A total of 170 
      patients were included. All 3 low-gradient variants had significant improvement 
      in NYHA class and KCCQ overall scores at 30 days and 1 year. There were no 
      significant differences in KCCQ overall scores between the 3 groups and no 
      significant differences in secondary outcomes. Patients with low-gradient aortic 
      stenosis experienced significant improvements in functional and quality-of-life 
      outcomes following TAVR.
CI  - Copyright (c) 2023 Elsevier Inc. All rights reserved.
FAU - Chiang, Caleb
AU  - Chiang C
AD  - Rush University Medical Center, Chicago, IL.
FAU - Brandon, Margaret
AU  - Brandon M
AD  - Rush University Medical Center, Chicago, IL. Electronic address: 
      margaret_e_brandon@rush.edu.
FAU - Danley, Kelsey
AU  - Danley K
AD  - Rush University Medical Center, Chicago, IL.
FAU - Luo, Shengyuan
AU  - Luo S
AD  - Rush University Medical Center, Chicago, IL.
FAU - Honasoge, Akilesh
AU  - Honasoge A
AD  - Rush University Medical Center, Chicago, IL.
FAU - Derbas, Laith A
AU  - Derbas LA
AD  - Rush University Medical Center, Chicago, IL.
FAU - Jolly, Neeraj
AU  - Jolly N
AD  - Rush University Medical Center, Chicago, IL.
FAU - Collado, Fareed
AU  - Collado F
AD  - Rush University Medical Center, Chicago, IL.
FAU - Kavinsky, Clifford J
AU  - Kavinsky CJ
AD  - Rush University Medical Center, Chicago, IL.
FAU - Suradi, Hussam S
AU  - Suradi HS
AD  - Rush University Medical Center, Chicago, IL.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230716
PL  - Netherlands
TA  - Curr Probl Cardiol
JT  - Current problems in cardiology
JID - 7701802
SB  - IM
MH  - Humans
MH  - Quality of Life
MH  - *Transcatheter Aortic Valve Replacement/adverse effects
MH  - Health Status
MH  - Retrospective Studies
MH  - *Aortic Valve Stenosis/surgery
MH  - Treatment Outcome
MH  - Aortic Valve/surgery
MH  - Risk Factors
MH  - Severity of Illness Index
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/07/17 00:42
MHDA- 2023/12/17 09:44
CRDT- 2023/07/16 19:26
PHST- 2023/06/27 00:00 [received]
PHST- 2023/07/04 00:00 [accepted]
PHST- 2023/12/17 09:44 [medline]
PHST- 2023/07/17 00:42 [pubmed]
PHST- 2023/07/16 19:26 [entrez]
AID - S0146-2806(23)00358-4 [pii]
AID - 10.1016/j.cpcardiol.2023.101941 [doi]
PST - ppublish
SO  - Curr Probl Cardiol. 2024 Jan;49(1 Pt A):101941. doi: 
      10.1016/j.cpcardiol.2023.101941. Epub 2023 Jul 16.