PMID- 37456051 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230718 IS - 2405-8440 (Print) IS - 2405-8440 (Electronic) IS - 2405-8440 (Linking) VI - 9 IP - 7 DP - 2023 Jul TI - Cardiac imaging for the prediction of sudden cardiac arrest in patients with heart failure. PG - e17710 LID - 10.1016/j.heliyon.2023.e17710 [doi] LID - e17710 AB - The identification of heart failure (HF) patients at risk for arrhythmic sudden cardiac arrest (SCA) is a major challenge in the cardiovascular field. In addition to optimal medical treatment for HF, implantable cardioverter defibrillator (ICD) is currently recommended to prevent SCA in patients with reduced left ventricular ejection fraction (LVEF). The indication for an ICD implantation, in addition to HF etiology, New York Health Association (NYHA) class and life expectancy, mainly depends on LVEF value at echocardiography. However, the actual role of LVEF in the prediction of SCA has recently been debated, while newer multimodality imaging techniques with increased prognostic accuracy have been developed. Speckle tracking imaging allows the quantification of mechanical dispersion, a marker of electrophysiological heterogeneity predisposing to malignant arrhythmias, while advanced cardiac magnetic resonance techniques such as myocardial T1-mapping and extracellular volume fraction assessment allow the evaluation of interstitial diffuse fibrosis. Nuclear imaging is helpful for the appraisal of sympathetic nervous system dysfunction, while newer computed tomography techniques assessing myocardial delayed enhancement allow the identification of focal myocardial scar. This review will focus on the most modern advances in the field of cardiovascular imaging along with its applications for the prediction of SCA in patients with HF. Modern artificial intelligence applications in cardiovascular imaging will also be discussed. CI - (c) 2023 The Authors. Published by Elsevier Ltd. FAU - De Lio, Francesca AU - De Lio F AD - Division of Cardiology, Citta della Salute e della Scienza di Torino University Hospital, University of Torino, Turin, Italy. FAU - Andreis, Alessandro AU - Andreis A AD - Division of Cardiology, Citta della Salute e della Scienza di Torino University Hospital, University of Torino, Turin, Italy. FAU - De Lio, Giulia AU - De Lio G AD - Division of Cardiology, Citta della Salute e della Scienza di Torino University Hospital, University of Torino, Turin, Italy. FAU - Bellettini, Matteo AU - Bellettini M AD - Division of Cardiology, Citta della Salute e della Scienza di Torino University Hospital, University of Torino, Turin, Italy. FAU - Pidello, Stefano AU - Pidello S AD - Division of Cardiology, Citta della Salute e della Scienza di Torino University Hospital, University of Torino, Turin, Italy. FAU - Raineri, Claudia AU - Raineri C AD - Division of Cardiology, Citta della Salute e della Scienza di Torino University Hospital, University of Torino, Turin, Italy. FAU - Gallone, Guglielmo AU - Gallone G AD - Division of Cardiology, Citta della Salute e della Scienza di Torino University Hospital, University of Torino, Turin, Italy. FAU - Alunni, Gianluca AU - Alunni G AD - Division of Cardiology, Citta della Salute e della Scienza di Torino University Hospital, University of Torino, Turin, Italy. FAU - Frea, Simone AU - Frea S AD - Division of Cardiology, Citta della Salute e della Scienza di Torino University Hospital, University of Torino, Turin, Italy. FAU - Imazio, Massimo AU - Imazio M AD - Cardiology Unit, Cardiothoracic Department, University Hospital "Santa Maria della Misericordia", Udine, Italy. FAU - Castagno, Davide AU - Castagno D AD - Division of Cardiology, Citta della Salute e della Scienza di Torino University Hospital, University of Torino, Turin, Italy. FAU - De Ferrari, Gaetano Maria AU - De Ferrari GM AD - Division of Cardiology, Citta della Salute e della Scienza di Torino University Hospital, University of Torino, Turin, Italy. LA - eng PT - Journal Article PT - Review DEP - 20230628 PL - England TA - Heliyon JT - Heliyon JID - 101672560 PMC - PMC10338975 OTO - NOTNLM OT - Arrhythmias OT - Cardiac imaging OT - Cardiac magnetic resonance OT - Diastole OT - Heart failure OT - ICD OT - Speckle tracking OT - Sudden death OT - Ventricular fibrillation OT - Ventricular tachycardia COIS- The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2023/07/17 06:42 MHDA- 2023/07/17 06:43 PMCR- 2023/06/28 CRDT- 2023/07/17 04:19 PHST- 2022/03/13 00:00 [received] PHST- 2023/06/11 00:00 [revised] PHST- 2023/06/26 00:00 [accepted] PHST- 2023/07/17 06:43 [medline] PHST- 2023/07/17 06:42 [pubmed] PHST- 2023/07/17 04:19 [entrez] PHST- 2023/06/28 00:00 [pmc-release] AID - S2405-8440(23)04918-6 [pii] AID - e17710 [pii] AID - 10.1016/j.heliyon.2023.e17710 [doi] PST - epublish SO - Heliyon. 2023 Jun 28;9(7):e17710. doi: 10.1016/j.heliyon.2023.e17710. eCollection 2023 Jul.