PMID- 37456472
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230718
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 15
IP  - 6
DP  - 2023 Jun
TI  - An Unusual Case of Acute Cholecystitis Caused by Lactobacillus paracasei.
PG  - e40334
LID - 10.7759/cureus.40334 [doi]
LID - e40334
AB  - Lactobacillus paracasei is a gram-positive rod commonly found in probiotic foods 
      and is well known to promote healthy gastrointestinal tracts. However, there have 
      been a few case reports that have found Lactobacillus paracasei to be the 
      causative agent in complications such as endocarditis, meningitis, peritonitis, 
      pancreatitis, and cholecystitis. We present the case of a 76-year-old woman who 
      was admitted for decompensated heart failure. The patient also reported abdominal 
      pain in the right upper quadrant. Ultrasound findings suggested cholelithiasis 
      and a subsequent hepatobiliary iminodiacetic acid (HIDA) scan confirmed acute 
      cholecystitis. This patient was not a good candidate for cholecystectomy because 
      of the risk of cardiac complications. Hence, percutaneous cholecystostomy tube 
      (PCT) placement was done, and the aspirate drained during the procedure was sent 
      for pathology. This bile culture was positive for Lactobacillus paracasei and 
      negative for any other kinds of bacteria. The incidence of Lactobacillus 
      species-induced cholecystitis makes up only 0.08% to 0.2% of cases, which makes 
      this an unusual case of acute cholecystitis caused by Lactobacillus paracasei. We 
      will discuss several pathogenic aspects of Lactobacillus paracasei, such as its 
      ability to generate biofilms, pore-forming toxins, drug transporters, and 
      antibiotic susceptibility.
CI  - Copyright (c) 2023, Kim et al.
FAU - Kim, Hui Un
AU  - Kim HU
AD  - Internal Medicine, American University of Antigua, New York City, USA.
FAU - Choo, Byeongyeon
AU  - Choo B
AD  - Internal Medicine, American University of Antigua, New York City, USA.
FAU - Pyakuryal, Arun
AU  - Pyakuryal A
AD  - Internal Medicine, Western Reserve Health Education/Northeast Ohio Medical 
      University (NEOMED), Warren, USA.
FAU - Shah, Munir
AU  - Shah M
AD  - Infectious Disease, Western Reserve Health Education/Northeast Ohio Medical 
      University (NEOMED), Warren, USA.
LA  - eng
PT  - Case Reports
DEP - 20230612
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC10338649
OTO - NOTNLM
OT  - acute cholecystitis
OT  - bile culture
OT  - gallbladder
OT  - lactobacillus
OT  - percutaneous cholecystostomy
COIS- The authors have declared that no competing interests exist.
EDAT- 2023/07/17 06:42
MHDA- 2023/07/17 06:43
PMCR- 2023/06/12
CRDT- 2023/07/17 04:24
PHST- 2023/06/07 00:00 [accepted]
PHST- 2023/07/17 06:43 [medline]
PHST- 2023/07/17 06:42 [pubmed]
PHST- 2023/07/17 04:24 [entrez]
PHST- 2023/06/12 00:00 [pmc-release]
AID - 10.7759/cureus.40334 [doi]
PST - epublish
SO  - Cureus. 2023 Jun 12;15(6):e40334. doi: 10.7759/cureus.40334. eCollection 2023 
      Jun.