PMID- 37460303
OWN - NLM
STAT- MEDLINE
DCOM- 20240126
LR  - 20240210
IS  - 2186-1005 (Electronic)
IS  - 1341-1098 (Print)
IS  - 1341-1098 (Linking)
VI  - 30
IP  - 1
DP  - 2024 Jan 25
TI  - A Predictive Nomogram for Intensive Care-Acquired Weakness after Cardiopulmonary 
      Bypass.
LID - 10.5761/atcs.oa.23-00029 [doi]
LID - 23-00029
AB  - PURPOSE: Intensive care unit-acquired weakness (ICUAW) affects patient prognosis 
      after cardiopulmonary bypass (CPB) surgery, but its risk factors remain unclear. 
      We investigated these risk factors and developed a nomogram for predicting ICUAW 
      after CPB. METHODS: Baseline characteristics, preoperative laboratory data, and 
      intra- and postoperative variables of 473 patients after CPB were determined in 
      this prospective cohort study. Lower limb muscles on bedside ultrasound images 
      were compared 1 day before and 7 days after CPB. Risk factors were assessed using 
      logistic regression models. RESULTS: Approximately 50.95% of the patients 
      developed ICUAW after CPB. The body mass index (BMI), New York Heart Association 
      (NYHA) class, lactate, albumin, aortic clamping time, operation time, and acute 
      physiological and chronic health evaluation II were determined as independent 
      risk factors. The average absolute error of coincidence was 0.019; the area under 
      the curve, sensitivity, and specificity were 0.811, 0.727, and 0.733, 
      respectively, for the predictive nomogram. CONCLUSION: A high BMI, poor NYHA 
      class, preoperative high serum lactate, low serum albumin, long surgical 
      duration, aortic clamping, and high acute physiological and chronic health 
      evaluation II score are risk factors for ICUAW after CPB. This robust and 
      easy-to-use nomogram was developed for clinical decision-making.
FAU - Zhong, Fuxiu
AU  - Zhong F
AD  - Department of Nursing, Fujian Medical University Union Hospital, Fuzhou, China.
FAU - Zhang, Haoruo
AU  - Zhang H
AD  - Department of Plastic Surgery, Fujian Medical University Union Hospital, Fuzhou, 
      China.
FAU - Peng, Yanchun
AU  - Peng Y
AD  - Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, 
      China.
FAU - Lin, Xueying
AU  - Lin X
AD  - Department of Ultrasound, Fujian Medical University Union Hospital, Fuzhou, 
      China.
FAU - Chen, Liangwan
AU  - Chen L
AD  - Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, 
      China.
AD  - Heart Medicine Research Center, Fujian Medical University Union Hospital, Fuzhou, 
      China.
FAU - Lin, Yanjuan
AU  - Lin Y
AD  - Department of Nursing, Fujian Medical University Union Hospital, Fuzhou, China.
AD  - Heart Medicine Research Center, Fujian Medical University Union Hospital, Fuzhou, 
      China.
LA  - eng
PT  - Journal Article
DEP - 20230715
PL  - Japan
TA  - Ann Thorac Cardiovasc Surg
JT  - Annals of thoracic and cardiovascular surgery : official journal of the 
      Association of Thoracic and Cardiovascular Surgeons of Asia
JID - 9703158
RN  - 0 (Lactates)
SB  - IM
MH  - Humans
MH  - *Cardiopulmonary Bypass/adverse effects
MH  - *Nomograms
MH  - Prospective Studies
MH  - Treatment Outcome
MH  - Risk Factors
MH  - Critical Care
MH  - Lactates
PMC - PMC10851444
OTO - NOTNLM
OT  - cardiopulmonary bypass
OT  - circulation
OT  - intensive care unit-acquired weakness
OT  - nomogram
OT  - risk factor
COIS- The authors declare no conflict of interest.
EDAT- 2023/07/18 01:09
MHDA- 2024/01/26 06:43
PMCR- 2024/01/01
CRDT- 2023/07/17 21:53
PHST- 2024/01/26 06:43 [medline]
PHST- 2023/07/18 01:09 [pubmed]
PHST- 2023/07/17 21:53 [entrez]
PHST- 2024/01/01 00:00 [pmc-release]
AID - atcs.oa.23-00029 [pii]
AID - 10.5761/atcs.oa.23-00029 [doi]
PST - ppublish
SO  - Ann Thorac Cardiovasc Surg. 2024 Jan 25;30(1):23-00029. doi: 
      10.5761/atcs.oa.23-00029. Epub 2023 Jul 15.