PMID- 37465058
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230720
IS  - 1177-889X (Print)
IS  - 1177-889X (Electronic)
IS  - 1177-889X (Linking)
VI  - 17
DP  - 2023
TI  - Determinants of Medication Non-Adherence Among the Elderly with Co-Existing 
      Hypertension and Type 2 Diabetes Mellitus in Rural Areas of Udupi District in 
      Karnataka, India.
PG  - 1641-1656
LID - 10.2147/PPA.S380784 [doi]
AB  - PURPOSE: Medication adherence is a crucial component in the management of elderly 
      with co-morbid chronic conditions. Hence, this study aimed to investigate the 
      determinants of medication non-adherence among rural elderly with co-morbid 
      chronic conditions of hypertension (HTN) and type 2 diabetes mellitus (T2DM) in 
      India. PATIENTS AND METHODS: This cross-sectional study adopted the probability 
      proportional to size (PPS) sampling technique to find the determinants of 
      medication non-adherence among elderly residing in rural coverage areas of five 
      randomly selected primary health centres (PHC) in Udupi district, Karnataka, 
      India. A total of 360 elderly (72 samples from each cluster) who met the 
      inclusion criteria and consented were interviewed using predesigned prevalidated 
      and standardized or reliable tools. The data were coded and entered in SPSS 
      version 16.0 and analyzed using both descriptive and inferential statistics. 
      RESULTS: The study found that 55.6% (n=200) of rural elderly with co-morbid 
      conditions HTN and T2DM were non-adherent to their medications and established 
      Spearman correlation coefficient rank (r) value between undesirable 
      person-related factors (r=-0.444); good family support (including financial 
      support) (r=0.185); poor accessibility to healthcare facility (r=-0.209); 
      detrimental medication-related factors including high cost of medication 
      (r=-0.237) were found to be significant at 0.05 level of confidence (p < 0.05). 
      Further, the study depicted that the chi-square test (chi(2)) was identified to be 
      significantly associated (p<0.05) with a variable such as education, knowledge, 
      number of illnesses and impairments, vision, memory, and physical impairments. 
      CONCLUSION: Medication adherence could be improved among rural elderly with 
      co-morbid conditions by identifying and addressing the determinants at the 
      earliest. Further, it is vital to identify the suitable intervention program to 
      address these avoidable problems.
CI  - (c) 2023 K et al.
FAU - K, Jeyalakshmi
AU  - K J
AUID- ORCID: 0000-0003-2280-2787
AD  - Department of Community Health Nursing, Manipal College of Nursing, Manipal 
      Academy of Higher Education, Manipal, Karnataka, India.
FAU - Rao, Mahadev
AU  - Rao M
AD  - Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, 
      Manipal Academy of Higher Education, Manipal, Karnataka, India.
FAU - Yn, Shashidhara
AU  - Yn S
AD  - Department of Community Health Nursing, Manipal College of Nursing, Manipal 
      Academy of Higher Education, Manipal, Karnataka, India.
FAU - Thunga, Girish
AU  - Thunga G
AD  - Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, 
      Manipal Academy of Higher Education, Manipal, Karnataka, India.
FAU - N, Ravishankar
AU  - N R
AD  - Department of Biostatistics, Vallabhbhai Patel Chest Institute, University of 
      Delhi, Delhi, India.
FAU - Sudhakar, Christopher
AU  - Sudhakar C
AD  - Department of Mental Health Nursing & Director - Quality, Manipal Academy of 
      Higher Education, Manipal, Karnataka, India.
FAU - Sanatombi Devi, Elsa
AU  - Sanatombi Devi E
AD  - Department of Medical Surgical Nursing, Manipal College of Nursing, Manipal 
      Academy of Higher Education, Manipal, Karnataka, India.
LA  - eng
PT  - Journal Article
DEP - 20230713
PL  - New Zealand
TA  - Patient Prefer Adherence
JT  - Patient preference and adherence
JID - 101475748
PMC - PMC10351531
OTO - NOTNLM
OT  - drug compliance
OT  - factors
OT  - multiple chronic conditions
OT  - old age people
COIS- The authors report no conflicts of interest in this work.
EDAT- 2023/07/19 06:43
MHDA- 2023/07/19 06:44
PMCR- 2023/07/13
CRDT- 2023/07/19 03:54
PHST- 2023/01/27 00:00 [received]
PHST- 2023/06/08 00:00 [accepted]
PHST- 2023/07/19 06:44 [medline]
PHST- 2023/07/19 06:43 [pubmed]
PHST- 2023/07/19 03:54 [entrez]
PHST- 2023/07/13 00:00 [pmc-release]
AID - 380784 [pii]
AID - 10.2147/PPA.S380784 [doi]
PST - epublish
SO  - Patient Prefer Adherence. 2023 Jul 13;17:1641-1656. doi: 10.2147/PPA.S380784. 
      eCollection 2023.