PMID- 37469762 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230721 IS - 2734-1461 (Electronic) IS - 2765-4559 (Print) IS - 2734-1461 (Linking) VI - 1 IP - 2 DP - 2021 Apr TI - Cerebral Toxocara canis larval infection presenting as delayed encephalopathy and nonconvulsive status epilepticus: a case report. PG - 51-55 LID - 10.47936/encephalitis.2021.00024 [doi] AB - Adult cerebral Toxocara canis larval infections are rare. Humans are infected by contacting soil that contains infectious eggs or by eating undercooked meat. We encountered a patient with cerebral T. canis infection who showed recurrent altered mentality with nonconvulsive status epilepticus (NCSE). A 71-year-old male was admitted with complaints of drowsy mentality and abnormal behavior. Magnetic resonance imaging revealed non-enhanced multiple gliosis and calcified lesions. Electroencephalography revealed NCSE, which was cured with valproate. However, he was readmitted because of recurrence of symptoms. On cerebrospinal fluid examination, T. canis antibodies were observed. Subsequently, he was treated with albendazole and corticosteroids. Although corticosteroid improved his symptoms, the therapy could not be continued because the patient developed septic shock. This is the first report of cerebral T. canis larval infection presenting as delayed encephalopathy and NCSE. In patients with unexplainable progressive encephalopathy, particularly when gliosis or calcified lesions are observed on neuroimaging, cerebral T. canis larval infection should be considered and treated promptly. CI - Copyright (c) 2021 Korean Encephalitis and Neuroinflammation Society. FAU - Lee, Jung-Ju AU - Lee JJ AUID- ORCID: 0000-0001-7498-5656 AD - Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea. FAU - Kang, Kyusik AU - Kang K AD - Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea. FAU - Lee, Woong-Woo AU - Lee WW AD - Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea. FAU - Kim, Byung-Kun AU - Kim BK AD - Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea. FAU - Park, Jong-Moo AU - Park JM AD - Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea. FAU - Kwon, Ohyun AU - Kwon O AD - Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea. FAU - Cho, Soohyun AU - Cho S AD - Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea. LA - eng PT - Case Reports DEP - 20210405 PL - Korea (South) TA - Encephalitis JT - Encephalitis (Seoul, Korea) JID - 9918592381006676 PMC - PMC10295886 OTO - NOTNLM OT - Adrenal cortex hormones OT - Albendazole OT - Status epilepticus OT - Toxocara canis COIS- Conflicts of Interest No potential conflict of interest relevant to this article was reported. EDAT- 2021/04/01 00:00 MHDA- 2021/04/01 00:01 PMCR- 2021/04/01 CRDT- 2023/07/20 04:08 PHST- 2021/02/03 00:00 [received] PHST- 2021/03/03 00:00 [revised] PHST- 2021/03/10 00:00 [accepted] PHST- 2021/04/01 00:01 [medline] PHST- 2021/04/01 00:00 [pubmed] PHST- 2023/07/20 04:08 [entrez] PHST- 2021/04/01 00:00 [pmc-release] AID - encephalitis-2021-00024 [pii] AID - 10.47936/encephalitis.2021.00024 [doi] PST - ppublish SO - Encephalitis. 2021 Apr;1(2):51-55. doi: 10.47936/encephalitis.2021.00024. Epub 2021 Apr 5.