PMID- 37475674
OWN - NLM
STAT- MEDLINE
DCOM- 20231004
LR  - 20231004
IS  - 0300-0729 (Print)
IS  - 0300-0729 (Linking)
VI  - 61
IP  - 5
DP  - 2023 Oct 1
TI  - Septoplasty and/or inferior turbinoplasty produce significant improvements of the 
      sense of smell.
PG  - 421-431
LID - 10.4193/Rhin22.461 [doi]
AB  - BACKGROUND: Patients with septal deviation and/or turbinal hypertrophy may 
      experience olfactory disfunction (OD). The aim of this study was to analyse the 
      effect of septoplasty and/or turbinoplasty on both lateralized and bilateral 
      olfactory function. METHODOLOGY: Prospective study of 47 patients with nasal 
      obstruction secondary to septal deviation and/or turbinal hypertrophy and 20 
      healthy controls. The Barcelona Olfactory test (BOT-8), a new supraliminal 
      orthonasal subjective olfactometry, was applied 3 times in a row (in each nostril 
      separately and in both simultaneously). The 8 items were applied randomly to 
      minimize the possible risk of learning. The test has not established the minimal 
      clinically important difference (MCID). Anterior rhinomanometry and acoustic 
      rhinometry were performed. All participants self-assessed smell loss and nasal 
      obstruction using a visual analogue scale (VAS) and completed questionnaires for 
      nasal obstruction (Nasal Obstruction Symptom Evaluation, NOSE) and for quality of 
      life (QoL), using disease-specific (SinoNasal Outcome Test-22, SNOT-22) and 
      generic (Short Form-12 Health Survey, SF-12) questionnaires. Nasal measurements 
      and questionnaires were performed preoperatively and 12 months after surgery. 
      RESULTS: Before surgery, patients reported worse VAS on smell loss and on nasal 
      obstruction compared to controls. Patients scored lower BOT-8 than controls. 
      Lateralized preoperative olfactory function showed that all BOT-8 characteristics 
      were lower at the narrow side than the wider one. Smell function and QoL improved 
      significantly one year after surgery. CONCLUSIONS: Nasal septal deviation and 
      turbinal hypertrophy lead to an olfactory impairment on the obstructed nostril. 
      Nasal surgery provides a positive outcome on olfactory function, as well as on 
      subjective and objective outcomes.
FAU - Mackers, P
AU  - Mackers P
AD  - Rhinology and Skull Base Units, Smell Clinic, Otorhinolaryngology Department 
      Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Catalonia, 
      Spain; and Otorhinolaryngology Department, Hospital del Mar, Barcelona, 
      Catalonia, Spain.
FAU - Rojas-Lechuga, M J
AU  - Rojas-Lechuga MJ
AD  - Rhinology and Skull Base Units, Smell Clinic, Otorhinolaryngology Department 
      Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Catalonia, 
      Spain.
FAU - Langdon, C
AU  - Langdon C
AD  - Rhinology and Skull Base Units, Smell Clinic, Otorhinolaryngology Department 
      Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Catalonia, 
      Spain; and Otorhinolaryngology Department, Hospital Sant Joan de Deu, Barcelona, 
      Catalonia, Spain.
FAU - NoguA S, A
AU  - NoguA S A
AD  - Rhinology and Skull Base Units, Smell Clinic, Otorhinolaryngology Department 
      Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Catalonia, 
      Spain; and Otorhinolaryngology Department Consorci Sanitari Alt Penedes Garraf. 
      Barcelona, Catalonia, Spain.
FAU - Mullol, J
AU  - Mullol J
AD  - Rhinology and Skull Base Units, Smell Clinic, Otorhinolaryngology Department 
      Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Catalonia, 
      Spain; and Clinical and Experimental Respiratory Immunollergy, IDIBAPS, 
      Barcelona, Catalonia, Spain; and CIBER of Respiratory Diseases (CIBERES), Health 
      Institute Carlos III, Spain.
FAU - Alobid, I
AU  - Alobid I
AD  - Rhinology and Skull Base Units, Smell Clinic, Otorhinolaryngology Department 
      Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Catalonia, 
      Spain; and Clinical and Experimental Respiratory Immunollergy, IDIBAPS, 
      Barcelona, Catalonia, Spain; and CIBER of Respiratory Diseases (CIBERES), Health 
      Institute Carlos III, Spain; and Unidad Alergo Rino, Centro Medico Teknon, 
      Barcelona, Catalonia, Spain.
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Rhinology
JT  - Rhinology
JID - 0347242
SB  - IM
MH  - Humans
MH  - Smell
MH  - Quality of Life
MH  - *Nasal Obstruction/surgery/diagnosis
MH  - Prospective Studies
MH  - Anosmia/surgery
MH  - Treatment Outcome
MH  - *Rhinoplasty
MH  - Nasal Septum/surgery
MH  - *Nose Deformities, Acquired/surgery
EDAT- 2023/07/21 06:43
MHDA- 2023/10/04 06:44
CRDT- 2023/07/21 03:36
PHST- 2023/10/04 06:44 [medline]
PHST- 2023/07/21 06:43 [pubmed]
PHST- 2023/07/21 03:36 [entrez]
AID - 3098 [pii]
AID - 10.4193/Rhin22.461 [doi]
PST - ppublish
SO  - Rhinology. 2023 Oct 1;61(5):421-431. doi: 10.4193/Rhin22.461.