PMID- 37479006
OWN - NLM
STAT- MEDLINE
DCOM- 20231216
LR  - 20231216
IS  - 1535-6280 (Electronic)
IS  - 0146-2806 (Linking)
VI  - 48
IP  - 12
DP  - 2023 Dec
TI  - Therapeutic Outcomes Following Isolated Transcatheter Tricuspid Valve Repair: A 
      Systematic Review and Meta-analysis.
PG  - 101985
LID - S0146-2806(23)00402-4 [pii]
LID - 10.1016/j.cpcardiol.2023.101985 [doi]
AB  - Tricuspid regurgitation (TR) is traditionally treated surgically, but isolated 
      transcatheter tricuspid valve repair (ITTVR) offers a less invasive option. This 
      study conducts a meta-analysis and systematic review to evaluate ITTVR outcomes 
      in patients with TR. Database searches until March 2023 identified studies 
      assessing ITTVR safety and efficacy in moderate/severe TR patients. Primary 
      outcomes analyzed were severe TR, NYHA functional class improvement, and 6-minute 
      walking distance. Meta-analyses used Risk ratio (RR) or mean difference with a 
      random effects model. The review included 25 studies with 2421 patients. ITTVR 
      improved NYHA functional class (RR: 3.262), reduced TR severity (RR: 0.303), and 
      enhanced 6-minute walking distance (MD: +47.077 m). Echocardiographic parameters 
      improved, including reductions in TR vena contracta, TR EROA, septolateral 
      tricuspid annular diameter, RVEDD, RV FAC, and TAPSE. LVEF and PASP showed no 
      significant changes. ITTVR improves functional outcomes and echocardiographic 
      parameters in TR patients.
CI  - Copyright (c) 2023 Elsevier Inc. All rights reserved.
FAU - Siddiqui, Hasan Fareed
AU  - Siddiqui HF
AD  - Department of Internal Medicine, Dow University of Health Sciences, Karachi, 
      Sindh, Pakistan.
FAU - Khan, Adam Bilal
AU  - Khan AB
AD  - Department of Internal Medicine, Dow University of Health Sciences, Karachi, 
      Sindh, Pakistan. Electronic address: adamkhan711@yahoo.com.
FAU - Nasir, Muhammad Moiz
AU  - Nasir MM
AD  - Department of Internal Medicine, Dow University of Health Sciences, Karachi, 
      Sindh, Pakistan.
FAU - Latif, Fakhar
AU  - Latif F
AD  - Department of Internal Medicine, Dow University of Health Sciences, Karachi, 
      Sindh, Pakistan.
FAU - Siddiqui, Aisha Fareed
AU  - Siddiqui AF
AD  - Department of Internal Medicine, Aga Khan University Hospital, Karachi, Sindh, 
      Pakistan.
FAU - Akhtar, Parveen
AU  - Akhtar P
AD  - Department of Cardiology, National Institute of Cardiovascular Diseases, Karachi, 
      Sindh, Pakistan.
FAU - Hamza, Mohammad
AU  - Hamza M
AD  - Department of Internal Medicine, Albany Medical Center, Albany, NY.
FAU - Barmanwalla, Alina
AU  - Barmanwalla A
AD  - Department of Internal Medicine, MD Brigham and Women's Hospital and Cape Cod 
      Hospital, Boston, MA.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20230719
PL  - Netherlands
TA  - Curr Probl Cardiol
JT  - Current problems in cardiology
JID - 7701802
SB  - IM
MH  - Humans
MH  - Tricuspid Valve/diagnostic imaging/surgery
MH  - Treatment Outcome
MH  - *Tricuspid Valve Insufficiency/surgery
MH  - Echocardiography
MH  - *Heart Valve Prosthesis Implantation/adverse effects
MH  - Severity of Illness Index
MH  - Cardiac Catheterization
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/07/22 10:42
MHDA- 2023/12/17 09:43
CRDT- 2023/07/21 19:23
PHST- 2023/07/06 00:00 [received]
PHST- 2023/07/16 00:00 [accepted]
PHST- 2023/12/17 09:43 [medline]
PHST- 2023/07/22 10:42 [pubmed]
PHST- 2023/07/21 19:23 [entrez]
AID - S0146-2806(23)00402-4 [pii]
AID - 10.1016/j.cpcardiol.2023.101985 [doi]
PST - ppublish
SO  - Curr Probl Cardiol. 2023 Dec;48(12):101985. doi: 10.1016/j.cpcardiol.2023.101985. 
      Epub 2023 Jul 19.