PMID- 37488834
OWN - NLM
STAT- MEDLINE
DCOM- 20231110
LR  - 20231117
IS  - 2005-6648 (Electronic)
IS  - 1226-3303 (Print)
IS  - 1226-3303 (Linking)
VI  - 38
IP  - 6
DP  - 2023 Nov
TI  - Nailfold capillaroscopy findings of interstitial pneumonia with autoimmune 
      features.
PG  - 903-911
LID - 10.3904/kjim.2022.358 [doi]
AB  - BACKGROUND/AIMS: We evaluated nailfold capillaroscopy (NFC) of interstitial 
      pneumonia with autoimmune features (IPAF) and compared it with that of patients 
      with connective tissue disease-interstitial lung disease (CTD-ILD) and idiopathic 
      interstitial pneumonia (IIP). METHODS: Patients with newly diagnosed as ILD were 
      evaluated using NFC. Baseline demographic, clinical, serological, and 
      high-resolution CT findings were collected. NFC was semi-quantitatively scored 
      with six domains ranging from 0 to 18. In addition, the overall patterns 
      (scleroderma/non-scleroderma patterns) were determined. RESULTS: A total of 81 
      patients (31 with CTD-ILD, 18 with IPAF, and 32 with IIP) were included. The 
      non-specific interstitial pneumonia pattern was the most common ILD pattern in 
      the CTD-ILD and IPAF groups, whereas the usual interstitial pneumonia pattern was 
      the most common in the IIP group. The semi-quantitative score of the CTD-ILD 
      group was higher than that of the IPAF or IIP groups (5.8 vs 4.2 vs 3.0, p < 
      0.001, respectively). Giant capillaries and haemorrhages were more frequently 
      present in the CTD-ILD and IPAF groups than in the IIP group. A scleroderma 
      pattern was present in 27.8% of the IPAF group, whereas none of the IIP patients 
      showed a scleroderma pattern. CONCLUSION: NFC findings may be useful in 
      classifying patients with ILD into CTD-ILD/IPAF/IIP.
FAU - Lee, Sang-Heon
AU  - Lee SH
AD  - Division of Rheumatology, Department of Internal Medicine, Research Institute of 
      Medical Science, Konkuk University School of Medicine, Seoul, Korea.
FAU - Min, Hong Ki
AU  - Min HK
AD  - Division of Rheumatology, Department of Internal Medicine, Konkuk University 
      Medical Center, Seoul, Korea.
FAU - Kim, Se-Hee
AU  - Kim SH
AD  - Division of Rheumatology, Department of Internal Medicine, Konkuk University 
      Medical Center, Seoul, Korea.
AD  - Department of Rheumatology, Kyung Hee University Hospital at Gangdong, College of 
      Medicine, Kyung Hee University, Seoul, Korea.
FAU - Kim, Young Whan
AU  - Kim YW
AD  - Division of Pulmonary Medicine, Department of Internal Medicine, Konkuk 
      University School of Medicine, Seoul, Korea.
FAU - Yoo, Kwang Ha
AU  - Yoo KH
AD  - Division of Pulmonary Medicine, Department of Internal Medicine, Konkuk 
      University School of Medicine, Seoul, Korea.
FAU - Kim, Hee Joung
AU  - Kim HJ
AD  - Division of Pulmonary Medicine, Department of Internal Medicine, Konkuk 
      University School of Medicine, Seoul, Korea.
FAU - Kim, In Ae
AU  - Kim IA
AD  - Precision Medicine Lung Cancer Center, Konkuk University Medical Center, Seoul, 
      Korea.
FAU - Kim, Hae-Rim
AU  - Kim HR
AD  - Division of Rheumatology, Department of Internal Medicine, Research Institute of 
      Medical Science, Konkuk University School of Medicine, Seoul, Korea.
LA  - eng
GR  - Konkuk University/
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230725
PL  - Korea (South)
TA  - Korean J Intern Med
JT  - The Korean journal of internal medicine
JID - 8712418
SB  - IM
MH  - Humans
MH  - Microscopic Angioscopy
MH  - Tomography, X-Ray Computed
MH  - *Lung Diseases, Interstitial/diagnostic imaging
MH  - *Idiopathic Pulmonary Fibrosis
MH  - *Idiopathic Interstitial Pneumonias/diagnosis
MH  - *Connective Tissue Diseases/diagnosis/diagnostic imaging
PMC - PMC10636555
OTO - NOTNLM
OT  - Connective tissue disease
OT  - Idiopathic interstitial pneumonia
OT  - Interstitial pneumonia with autoimmune feature
OT  - Nailfold capillary
COIS- Conflicts of interest The authors disclose no conflicts.
EDAT- 2023/07/25 06:43
MHDA- 2023/11/10 06:44
PMCR- 2023/11/01
CRDT- 2023/07/25 01:18
PHST- 2022/11/15 00:00 [received]
PHST- 2023/05/18 00:00 [accepted]
PHST- 2023/11/10 06:44 [medline]
PHST- 2023/07/25 06:43 [pubmed]
PHST- 2023/07/25 01:18 [entrez]
PHST- 2023/11/01 00:00 [pmc-release]
AID - kjim.2022.358 [pii]
AID - kjim-2022-358 [pii]
AID - 10.3904/kjim.2022.358 [doi]
PST - ppublish
SO  - Korean J Intern Med. 2023 Nov;38(6):903-911. doi: 10.3904/kjim.2022.358. Epub 
      2023 Jul 25.