PMID- 37497698
OWN - NLM
STAT- MEDLINE
DCOM- 20240405
LR  - 20240405
IS  - 1875-6417 (Electronic)
IS  - 1573-3998 (Linking)
VI  - 20
IP  - 3
DP  - 2024
TI  - Metformin in Type 2 Diabetes: Evidence for its Beneficial Effects on Frailty and 
      Sarcopenia.
PG  - e270723219177
LID - 10.2174/1573399820666230727101141 [doi]
AB  - This narrative review aimed to discuss the potential interplay among frailty 
      syndrome, sarcopenia and metformin in type 2 diabetes mellitus (T2DM). There is 
      emerging evidence on the potential protective role of metformin on both frailty 
      and sarcopenia. However, results are not always consistent. Thus, further 
      research is needed to provide a definitive answer on any role of metformin in 
      improving frailty and/or sarcopenia in T2DM.
CI  - Copyright(c) Bentham Science Publishers; For any queries, please email at 
      epub@benthamscience.net.
FAU - Pyrgioti, Elisavet E
AU  - Pyrgioti EE
AUID- ORCID: 0000-0003-1016-9646
AD  - Pharmacist, Private Practice, Athens, Greece.
FAU - Karakousis, Nikolaos D
AU  - Karakousis ND
AUID- ORCID: 0000-0003-4882-7042
AD  - Second Department of Internal Medicine, Diabetes Centre-Diabetic Foot Clinic, 
      Democritus University of Thrace, Alexandroupolis, Greece.
FAU - Georgakopoulos, Petros N
AU  - Georgakopoulos PN
AD  - Primary Healthcare, Internal Medicine Department, Amarousion, Attica, Greece.
FAU - Papanas, Nikolaos
AU  - Papanas N
AUID- ORCID: 0000-0002-7320-785X
AD  - Second Department of Internal Medicine, Diabetes Centre-Diabetic Foot Clinic, 
      Democritus University of Thrace, Alexandroupolis, Greece.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United Arab Emirates
TA  - Curr Diabetes Rev
JT  - Current diabetes reviews
JID - 101253260
RN  - 9100L32L2N (Metformin)
SB  - IM
MH  - Humans
MH  - Aged
MH  - *Diabetes Mellitus, Type 2/complications/drug therapy
MH  - *Metformin/therapeutic use
MH  - *Frailty/drug therapy
MH  - *Sarcopenia/drug therapy
MH  - Frail Elderly
OTO - NOTNLM
OT  - Metformin
OT  - T2DM.
OT  - antidiabetic drugs
OT  - frailty
OT  - low muscle mass
OT  - sarcopenia
EDAT- 2023/07/27 06:42
MHDA- 2024/04/05 06:44
CRDT- 2023/07/27 05:53
PHST- 2023/03/24 00:00 [received]
PHST- 2023/06/01 00:00 [revised]
PHST- 2023/06/27 00:00 [accepted]
PHST- 2024/04/05 06:44 [medline]
PHST- 2023/07/27 06:42 [pubmed]
PHST- 2023/07/27 05:53 [entrez]
AID - CDR-EPUB-133200 [pii]
AID - 10.2174/1573399820666230727101141 [doi]
PST - ppublish
SO  - Curr Diabetes Rev. 2024;20(3):e270723219177. doi: 
      10.2174/1573399820666230727101141.