PMID- 37501066
OWN - NLM
STAT- MEDLINE
DCOM- 20230731
LR  - 20230731
IS  - 1742-4755 (Electronic)
IS  - 1742-4755 (Linking)
VI  - 20
IP  - 1
DP  - 2023 Jul 27
TI  - Early sexual debut is associated with drug use and decreased educational 
      attainment among males and females in Kisumu County, Kenya.
PG  - 111
LID - 10.1186/s12978-023-01639-3 [doi]
LID - 111
AB  - Differing global sociocultural contexts of sexual relationships influence age at 
      first sexual intercourse with potentially long-lasting region-specific effects 
      such as increased risk of contracting HIV and other sexually transmitted 
      infections (STIs). In these cross-sectional analyses of data from the screening 
      and enrollment visits for an HIV incidence study in Kisumu County, Kenya, we 
      evaluated factors associated with having experienced an early sexual debut (ESD) 
      among males and females aged 18-35 years. Clinical evaluation was performed and 
      sexual behaviors were assessed via questionnaire. ESD was defined as 
      self-reported age 15 years or younger at first sexual intercourse. Robust Poisson 
      regression was used to estimate prevalence ratios (PRs) and 95% confidence 
      intervals (95% CIs) for factors associated with ESD. Of 1057 participants, 542 
      (51.3%) were female. Participants' median age at study screening was 25 years 
      (interquartile range [IQR]: 22-29), and at sexual debut was 16 years (IQR: 
      14-17). Five hundred and four participants (47.7%) reported ESD. ESD was less 
      common among females (PR 0.78, CI 0.67-0.90) and participants with more than 
      primary education (PR 0.56, CI 0.47-0.66). ESD was more common in participants 
      with a history of drug use (PR 1.28, CI 1.10-1.49). Drug use removed the 
      protective effect of education (some secondary education or less, no drug use: PR 
      0.72, CI 0.61-0.85; some secondary education or less, drug use: PR 0.94, CI 
      0.74-1.18). ESD was common in our study and associated with lower educational 
      attainment and increased likelihood of drug use. Interventions are needed early 
      in life, well before 15 years of age, to encourage engagement in schooling and 
      prevent drug use. Comprehensive sexual education and interventions to prevent 
      drug use may be beneficial before the age of 15 years.
CI  - (c) 2023. The Author(s).
FAU - Sing'oei, Valentine
AU  - Sing'oei V
AD  - HJF Medical Research International, Ole Odume Road, P.O. Box 37758-00100, 
      Nairobi, Kenya.
AD  - U.S. Army Medical Research Directorate, P.O. Box 54-40100, Kisumu, Kenya.
FAU - Owuoth, John K
AU  - Owuoth JK
AD  - HJF Medical Research International, Ole Odume Road, P.O. Box 37758-00100, 
      Nairobi, Kenya.
AD  - U.S. Army Medical Research Directorate, P.O. Box 54-40100, Kisumu, Kenya.
FAU - Otieno, June
AU  - Otieno J
AD  - U.S. Army Medical Research Directorate, P.O. Box 54-40100, Kisumu, Kenya.
FAU - Yates, Adam
AU  - Yates A
AD  - U.S. Military HIV Research Program, Walter Reed Army Institute of Research, 503 
      Robert Grant Ave, Silver Spring, MD, 20910, USA.
AD  - Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., 
      6720-A Rockledge Drive, Suite 100, Bethesda, MD, 20817, USA.
FAU - Andagalu, Ben
AU  - Andagalu B
AD  - U.S. Army Medical Research Directorate, P.O. Box 54-40100, Kisumu, Kenya.
FAU - Smith, Hunter J
AU  - Smith HJ
AD  - U.S. Army Medical Research Directorate, P.O. Box 54-40100, Kisumu, Kenya.
FAU - Copeland, Nathanial K
AU  - Copeland NK
AD  - U.S. Army Medical Research Directorate, P.O. Box 54-40100, Kisumu, Kenya.
FAU - Polyak, Christina S
AU  - Polyak CS
AD  - U.S. Military HIV Research Program, Walter Reed Army Institute of Research, 503 
      Robert Grant Ave, Silver Spring, MD, 20910, USA.
AD  - Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., 
      6720-A Rockledge Drive, Suite 100, Bethesda, MD, 20817, USA.
FAU - Crowell, Trevor A
AU  - Crowell TA
AD  - U.S. Military HIV Research Program, Walter Reed Army Institute of Research, 503 
      Robert Grant Ave, Silver Spring, MD, 20910, USA. tcrowell@hivresearch.org.
AD  - Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., 
      6720-A Rockledge Drive, Suite 100, Bethesda, MD, 20817, USA. 
      tcrowell@hivresearch.org.
CN  - RV393 Study Team
LA  - eng
PT  - Journal Article
DEP - 20230727
PL  - England
TA  - Reprod Health
JT  - Reproductive health
JID - 101224380
SB  - IM
MH  - Male
MH  - Humans
MH  - Female
MH  - Adult
MH  - Kenya/epidemiology
MH  - Cross-Sectional Studies
MH  - *Sexual Behavior
MH  - Educational Status
MH  - *HIV Infections/epidemiology
PMC - PMC10375697
OAB - Early sexual debut can be defined as first sexual intercourse at or before 
      15 years of age. There are many social and cultural factors that influence the 
      age of sexual debut. People who start having sex early in life may exhibit 
      behaviors that increase risk for HIV and other sexually transmitted infections. 
      We conducted a study of men and women aged 18-35 years in Kisumu County, Kenya, 
      which included documentation of medical history, physical examination, laboratory 
      tests, and a questionnaire to assess sexual behaviors. Among the 1057 people 
      studied, the average age of sexual debut was 16.0 years for females and 
      15.4 years for males. A total of 504 (47.7%) participants reported early sexual 
      debut. The data showed that early sexual debut was less common in females and in 
      participants with more years of education. Early sexual debut was more common in 
      participants with a history of drug use. The findings suggest that interventions 
      to prevent early sexual debut might be improved if they focus on educational 
      attainment and prevention of drug use.
OABL- eng
OTO - NOTNLM
OT  - Africa South of the Sahara
OT  - Early sexual debut
OT  - HIV
OT  - Kenya
OT  - Sex initiation
OT  - Sexual behavior
COIS- The authors declare that they have no competing interests.
FIR - Adongo, Rachel
IR  - Adongo R
FIR - Aguttu, Rachel
IR  - Aguttu R
FIR - Akala, Hosea
IR  - Akala H
FIR - Ake, Julie
IR  - Ake J
FIR - Bondo, Michael
IR  - Bondo M
FIR - Broach, Erica
IR  - Broach E
FIR - Busisa, Christine
IR  - Busisa C
FIR - Cowden, Jessica
IR  - Cowden J
FIR - de Souza, Mark
IR  - de Souza M
FIR - Eller, Leigh Anne
IR  - Eller LA
FIR - Gogo, Milicent
IR  - Gogo M
FIR - Hassen, Zebiba
IR  - Hassen Z
FIR - Hu, Dale
IR  - Hu D
FIR - Imbach, Michelle
IR  - Imbach M
FIR - Juma, Anne
IR  - Juma A
FIR - Kasera, Oscar
IR  - Kasera O
FIR - Li, Qun
IR  - Li Q
FIR - Mbuchi, Margaret
IR  - Mbuchi M
FIR - Milazzo, Mark
IR  - Milazzo M
FIR - Modjarrad, Kayvon
IR  - Modjarrad K
FIR - Ngonda, Eric
IR  - Ngonda E
FIR - Nwoga, Chiaka
IR  - Nwoga C
FIR - Nyariro, Jacob
IR  - Nyariro J
FIR - Ochola, Jew
IR  - Ochola J
FIR - Ohore, Roseline
IR  - Ohore R
FIR - Okumu, Thomas
IR  - Okumu T
FIR - Omondi, Mary
IR  - Omondi M
FIR - Omondi, Timothy
IR  - Omondi T
FIR - Ooro, Linnah
IR  - Ooro L
FIR - Orando, Beatrice
IR  - Orando B
FIR - Owira, Victorine
IR  - Owira V
FIR - Oyugi, Roselyn
IR  - Oyugi R
FIR - Robb, Merlin
IR  - Robb M
FIR - Rono, Eric
IR  - Rono E
FIR - Tran, Chi
IR  - Tran C
EDAT- 2023/07/28 01:08
MHDA- 2023/07/31 11:42
PMCR- 2023/07/27
CRDT- 2023/07/27 23:38
PHST- 2023/01/24 00:00 [received]
PHST- 2023/06/13 00:00 [accepted]
PHST- 2023/07/31 11:42 [medline]
PHST- 2023/07/28 01:08 [pubmed]
PHST- 2023/07/27 23:38 [entrez]
PHST- 2023/07/27 00:00 [pmc-release]
AID - 10.1186/s12978-023-01639-3 [pii]
AID - 1639 [pii]
AID - 10.1186/s12978-023-01639-3 [doi]
PST - epublish
SO  - Reprod Health. 2023 Jul 27;20(1):111. doi: 10.1186/s12978-023-01639-3.