PMID- 37507983
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230731
IS  - 2076-3921 (Print)
IS  - 2076-3921 (Electronic)
IS  - 2076-3921 (Linking)
VI  - 12
IP  - 7
DP  - 2023 Jul 18
TI  - Enhanced Polyphenols Recovery from Grape Pomace: A Comparison of Pressurized and 
      Atmospheric Extractions with Deep Eutectic Solvent Aqueous Mixtures.
LID - 10.3390/antiox12071446 [doi]
LID - 1446
AB  - Deep eutectic solvents (DES) are emerging as potent polyphenol extractors under 
      normal atmospheric conditions. Yet, their effectiveness in hot pressurized liquid 
      extraction (HPLE) must be studied more. We explored the ability of various 
      water/DES and water/hydrogen bond donors (HBDs) mixtures in both atmospheric 
      solid liquid extraction (ASLE) and HPLE (50%, 90  degrees C) for isolating specific 
      polyphenol families from Carmenere grape pomace. We assessed extraction yields 
      based on total polyphenols, antioxidant capacity, and recovery of targeted 
      polyphenols. The HBDs ethylene glycol and glycerol outperformed DES in 
      atmospheric and pressurized extractions. Ethylene glycol exhibited a higher 
      affinity for phenolic acids and flavonols, while flavanols preferred glycerol. 
      Quantum chemical computations indicated that a high-water content in DES mixtures 
      led to the formation of new hydrogen bonds, thereby reducing polyphenol-solvent 
      interactions. HPLE was found to be superior to ASLE across all tested solvents. 
      The elevated pressure in HPLE has caused significant improvement in the recovery 
      of flavanols (17-89%), phenolic acids (17-1000%), and flavonols (81-258%). 
      Scanning electron microscopy analysis of post-extraction residues suggested that 
      high pressures collapse the plant matrix, thus easing polyphenol release.
FAU - Huaman-Castilla, Nils Leander
AU  - Huaman-Castilla NL
AUID- ORCID: 0000-0002-3748-0883
AD  - Escuela de Ingenieria Agroindustrial, Universidad Nacional de Moquegua, 
      Prolongacion Calle Ancash s/n, Moquegua 18001, Peru.
FAU - Gajardo-Parra, Nicolas
AU  - Gajardo-Parra N
AD  - Chemical and Bioprocess Engineering Department, School of Engineering, Pontificia 
      Universidad Catolica de Chile, Vicuna Mackenna 4860, P.O. Box 306, Santiago 
      7820436, Chile.
FAU - Perez-Correa, Jose R
AU  - Perez-Correa JR
AUID- ORCID: 0000-0002-1278-7782
AD  - Chemical and Bioprocess Engineering Department, School of Engineering, Pontificia 
      Universidad Catolica de Chile, Vicuna Mackenna 4860, P.O. Box 306, Santiago 
      7820436, Chile.
FAU - Canales, Roberto I
AU  - Canales RI
AUID- ORCID: 0000-0002-2535-6527
AD  - Chemical and Bioprocess Engineering Department, School of Engineering, Pontificia 
      Universidad Catolica de Chile, Vicuna Mackenna 4860, P.O. Box 306, Santiago 
      7820436, Chile.
FAU - Martinez-Cifuentes, Maximiliano
AU  - Martinez-Cifuentes M
AUID- ORCID: 0000-0003-2959-3164
AD  - Departamento de Quimica Organica, Facultad de Ciencias Quimicas, Universidad de 
      Concepcion, Edmundo Larenas 129, Concepcion 4070371, Chile.
FAU - Contreras-Contreras, Gabriela
AU  - Contreras-Contreras G
AD  - Escuela de Nutricion y Dietetica, Facultad de Medicina, Universidad Finis Terrae, 
      Santiago 7501015, Chile.
FAU - Mariotti-Celis, Maria Salome
AU  - Mariotti-Celis MS
AUID- ORCID: 0000-0003-1357-812X
AD  - Escuela de Nutricion y Dietetica, Facultad de Medicina, Universidad Finis Terrae, 
      Santiago 7501015, Chile.
LA  - eng
GR  - 3160099/Agencia Nacional de Investigacion y Desarrollo/
GR  - Resolution C.O. N degrees  059-2021-UNAM/Universidad Nacional de Moquegua-Peru/
PT  - Journal Article
DEP - 20230718
PL  - Switzerland
TA  - Antioxidants (Basel)
JT  - Antioxidants (Basel, Switzerland)
JID - 101668981
PMC - PMC10376317
OTO - NOTNLM
OT  - antioxidant capacity
OT  - atmospheric extraction
OT  - deep eutectic solvents
OT  - grape pomace
OT  - hot pressurized liquid extraction
OT  - polyphenols
COIS- The authors declare no conflict of interest.
EDAT- 2023/07/29 11:45
MHDA- 2023/07/29 11:46
PMCR- 2023/07/18
CRDT- 2023/07/29 01:04
PHST- 2023/06/06 00:00 [received]
PHST- 2023/07/06 00:00 [revised]
PHST- 2023/07/14 00:00 [accepted]
PHST- 2023/07/29 11:46 [medline]
PHST- 2023/07/29 11:45 [pubmed]
PHST- 2023/07/29 01:04 [entrez]
PHST- 2023/07/18 00:00 [pmc-release]
AID - antiox12071446 [pii]
AID - antioxidants-12-01446 [pii]
AID - 10.3390/antiox12071446 [doi]
PST - epublish
SO  - Antioxidants (Basel). 2023 Jul 18;12(7):1446. doi: 10.3390/antiox12071446.