PMID- 37516874
OWN - NLM
STAT- MEDLINE
DCOM- 20230731
LR  - 20230803
IS  - 1475-2840 (Electronic)
IS  - 1475-2840 (Linking)
VI  - 22
IP  - 1
DP  - 2023 Jul 29
TI  - Smoking behavior change and risk of cardiovascular disease incidence and 
      mortality in patients with type 2 diabetes mellitus.
PG  - 193
LID - 10.1186/s12933-023-01930-4 [doi]
LID - 193
AB  - BACKGROUND: We aimed to examine the association between smoking behavior change 
      and risk of cardiovascular disease (CVD) incidence and mortality in patients with 
      type 2 diabetes mellitus (T2DM). METHODS: This study used nationwide data from 
      the Korean National Health Insurance System and included 349,137 T2DM patients 
      who smoked. Smoking behavior changes were defined with five groups: quitters, 
      reducers I (>/= 50% reduction), reducers II (20-50% reduction), sustainers (+/- 20%), 
      and increasers (>/= 20% increase) from the number of cigarettes/day at the 
      baseline. RESULTS: During a median follow-up of 5.1 years, 6,514 cases of 
      myocardial infarction (MI) (1.9%), 7,837 cases of ischemic stroke (IS) (2.2%), 
      and 14,932 deaths (4.3%) were identified. Quitters had a significantly decreased 
      risk of MI (adjusted hazard ratio [aHR] 0.80, 95% CI 0.75-0.86) and IS (aHR 0.80, 
      95% CI 0.75-0.85) compared to sustainers, whereas reducers did not have a 
      significant association with the risk of MI (aHR 1.03, 95% CI 0.94-1.13) and IS 
      (aHR 1.00, 95% CI 0.92-1.08) in reducer I. Quitters also had a lower all-cause 
      and CVD mortality than sustainers. CONCLUSIONS: Smoking cessation was associated 
      with decreased CVD incidence, and all-cause and CVD mortality among T2DM 
      patients. However, smoking reduction was not associated with decreased risks for 
      these.
CI  - (c) 2023. The Author(s).
FAU - Jeong, Su-Min
AU  - Jeong SM
AD  - Department of Medicine, Seoul National University College of Medicine, Seoul, 
      Republic of Korea.
AD  - Department of Family Medicine, Seoul National University Hospital, Seoul, 
      Republic of Korea.
AD  - Department of Family Medicine, Seoul National University Health Service Center, 
      Seoul, Republic of Korea.
FAU - Yoo, Jung Eun
AU  - Yoo JE
AD  - Department of Family Medicine, Seoul National University Hospital, Seoul, 
      Republic of Korea.
AD  - Department of Family Medicine, Healthcare System Gangnam Center, Seoul National 
      University Hospital, Seoul, Republic of Korea.
FAU - Park, Junhee
AU  - Park J
AD  - Department of Family Medicine, Samsung Medical Center, Sungkyunkwan University 
      School of Medicine, Seoul, Republic of Korea.
FAU - Jung, Wonyoung
AU  - Jung W
AD  - Department of Family Medicine/Obesity and Metabolic Health Center, Kangdong 
      Sacred Heart Hospital, Hallym University, Seoul, Republic of Korea.
FAU - Lee, Kyu Na
AU  - Lee KN
AD  - Department of Statistics and Actuarial Science, Soongsil University, Seoul, 
      Republic of Korea.
FAU - Han, Kyungdo
AU  - Han K
AD  - Department of Statistics and Actuarial Science, Soongsil University, Seoul, 
      Republic of Korea.
FAU - Lee, Cheol Min
AU  - Lee CM
AD  - Department of Family Medicine, Healthcare System Gangnam Center, Seoul National 
      University Hospital, Seoul, Republic of Korea.
AD  - Department of Family Medicine, Seoul National University College of Medicine, 
      Seoul, Republic of Korea.
FAU - Nam, Ki-Woong
AU  - Nam KW
AD  - Department of Neurology, Seoul National University College of Medicine and Seoul 
      Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, 
      Republic of Korea.
FAU - Lee, Seung-Pyo
AU  - Lee SP
AD  - Department of Internal Medicine and Cardiovascular Center, Seoul National 
      University Hospital, Seoul, Republic of Korea.
FAU - Shin, Dong Wook
AU  - Shin DW
AD  - Department of Family Medicine, Samsung Medical Center, Sungkyunkwan University 
      School of Medicine, Seoul, Republic of Korea. dwshin.md@gmail.com.
AD  - Department of Clinical Research Design & Evaluation, Samsung Advanced Institute 
      for Health Science & Technology (SAIHST), Sungkyunkwan University, 81 Irwon-Ro, 
      Gangnam-gu, Seoul, 06351, Republic of Korea. dwshin.md@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20230729
PL  - England
TA  - Cardiovasc Diabetol
JT  - Cardiovascular diabetology
JID - 101147637
SB  - IM
MH  - Humans
MH  - Incidence
MH  - *Cardiovascular Diseases/diagnosis/epidemiology
MH  - *Diabetes Mellitus, Type 2/diagnosis/epidemiology
MH  - Smoking/adverse effects/epidemiology
MH  - *Cardiovascular System
MH  - *Myocardial Infarction/diagnosis/epidemiology
MH  - *Ischemic Stroke
PMC - PMC10387213
OTO - NOTNLM
OT  - Cardiovascular disease
OT  - Diabetes mellitus
OT  - Mortality
OT  - Smoking cessation
OT  - Smoking reduction
COIS- All authors have no potential conflicts of interest to declare.
EDAT- 2023/07/30 01:06
MHDA- 2023/07/31 11:42
PMCR- 2023/07/29
CRDT- 2023/07/29 23:27
PHST- 2023/05/14 00:00 [received]
PHST- 2023/07/20 00:00 [accepted]
PHST- 2023/07/31 11:42 [medline]
PHST- 2023/07/30 01:06 [pubmed]
PHST- 2023/07/29 23:27 [entrez]
PHST- 2023/07/29 00:00 [pmc-release]
AID - 10.1186/s12933-023-01930-4 [pii]
AID - 1930 [pii]
AID - 10.1186/s12933-023-01930-4 [doi]
PST - epublish
SO  - Cardiovasc Diabetol. 2023 Jul 29;22(1):193. doi: 10.1186/s12933-023-01930-4.