PMID- 37523908
OWN - NLM
STAT- MEDLINE
DCOM- 20230823
LR  - 20230823
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1706
DP  - 2023 Sep 13
TI  - Three-dimensional fluorinated covalent organic frameworks coated capillary for 
      the separation of fluoroquinolones by capillary electrochromatography.
PG  - 464234
LID - S0021-9673(23)00459-4 [pii]
LID - 10.1016/j.chroma.2023.464234 [doi]
AB  - In this work, a three-dimensional fluorinated covalent organic frameworks (3D 
      FCOFs) JUC-515 was synthesized from tetra(4-aminophenyl)methane (TAM) and 
      2,3,5,6-tetrafluoroterephthalol (TFA) by an ionic liquid method. JUC-515 was 
      introduced into the capillary column and bonded to the inner wall of the 
      capillary column by chemical bonding. Through a variety of characterization 
      results, JUC-515 was successfully synthesized and introduced into the capillary 
      column. The effects of buffer solution concentration, organic additive content 
      and pH of the buffer solution on the separation of fluoroquinolones (FQs) were 
      investigated in detail. The JUC-515-coated capillary column showed good 
      resolution (>1.5) and reproducibility. The relative standard deviations (RSDs) of 
      the retention time for intraday, interday, column-to-column and interbatch 
      precision were less than 0.88%, 2.45%, 2.74% and 3.32%, respectively. The RSDs of 
      the peak area for intraday, interday, column-to-column and interbatch precision 
      were less than 3.79%, 4.31%, 3.33% and 5.62%, respectively. The JUC-515-coated 
      capillary column could be used no less than 150 times. The results showed that 
      the JUC-515-coated capillary column had good separation performance. In addition, 
      by separating fluorinated beta-phenylalanine analogs, beta-phenylalanine and 
      trifluoromethyl beta-phenylalanine analogs, the separation mechanism based on 
      fluorine interactions was discussed. In conclusion, JUC-515 had good potential as 
      a stationary phase for capillary electrochromatography.
CI  - Copyright (c) 2023. Published by Elsevier B.V.
FAU - Yin, Han
AU  - Yin H
AD  - Department of Chemistry, Capital Normal University, Beijing, 100048, PR China.
FAU - Zhen, Ziyi
AU  - Zhen Z
AD  - Department of Chemistry, Capital Normal University, Beijing, 100048, PR China.
FAU - Ning, Weijie
AU  - Ning W
AD  - Department of Chemistry, Capital Normal University, Beijing, 100048, PR China.
FAU - Zhang, Lu
AU  - Zhang L
AD  - Department of Chemistry, Capital Normal University, Beijing, 100048, PR China.
FAU - Xiang, Yuhong
AU  - Xiang Y
AD  - Department of Chemistry, Capital Normal University, Beijing, 100048, PR China. 
      Electronic address: xiangyh@cnu.edu.cn.
FAU - Ye, Nengsheng
AU  - Ye N
AD  - Department of Chemistry, Capital Normal University, Beijing, 100048, PR China. 
      Electronic address: yensh@cnu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20230722
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Metal-Organic Frameworks)
RN  - 0 (Fluoroquinolones)
RN  - 47E5O17Y3R (Phenylalanine)
SB  - IM
MH  - *Metal-Organic Frameworks/chemistry
MH  - *Capillary Electrochromatography/methods
MH  - Fluoroquinolones
MH  - Reproducibility of Results
MH  - Phenylalanine
OTO - NOTNLM
OT  - Fluorine interactions
OT  - Fluoroquinolones
OT  - Open-tubular capillary electrochromatography
OT  - Three-dimensional fluorinated covalent organic frameworks
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/08/01 01:08
MHDA- 2023/08/23 06:42
CRDT- 2023/07/31 18:05
PHST- 2023/05/24 00:00 [received]
PHST- 2023/07/18 00:00 [revised]
PHST- 2023/07/20 00:00 [accepted]
PHST- 2023/08/23 06:42 [medline]
PHST- 2023/08/01 01:08 [pubmed]
PHST- 2023/07/31 18:05 [entrez]
AID - S0021-9673(23)00459-4 [pii]
AID - 10.1016/j.chroma.2023.464234 [doi]
PST - ppublish
SO  - J Chromatogr A. 2023 Sep 13;1706:464234. doi: 10.1016/j.chroma.2023.464234. Epub 
      2023 Jul 22.