PMID- 37534503
OWN - NLM
STAT- MEDLINE
DCOM- 20230804
LR  - 20230804
IS  - 1526-3711 (Electronic)
IS  - 1526-3711 (Linking)
VI  - 24
IP  - 6
DP  - 2023 Jun 1
TI  - A Comparative Evaluation of Physical Parameters of Saliva and Correlation with 
      Periodontal Condition in Down Syndrome Children and Healthy Controls.
PG  - 372-380
LID - 10.5005/jp-journals-10024-3481 [doi]
AB  - AIM: The aim of this study was to assess the significance and role of physical 
      parameters of saliva on periodontal health in children with Down syndrome (DS). 
      MATERIALS AND METHODS: A comparative evaluation of physical parameters of saliva 
      such as flow rate, viscosity, pH, quantity and buffering capacity, and buffer 
      capacity was carried out using GC Saliva-Check Buffer kit and correlated with 
      periodontal condition examined using community periodontal index of treatment 
      needs (CPITN) in 40 DS subjects (group I) and 40 healthy controls (group II) aged 
      8-15 years. RESULTS: Down syndrome subjects had a low resting salivary flow rate, 
      moderately acidic saliva, very low quantity of stimulated saliva, and low 
      buffering capacity. On correlating salivary parameters with the periodontal 
      condition, DS subjects with CPITN code 1 had low resting salivary flow rate, 
      normal viscosity, moderately acidic pH, very low quantity of stimulated saliva, 
      and low buffering capacity. Down syndrome subjects with CPITN code 2 had low 
      resting flow rate, increased viscosity, very low quantity of stimulated saliva, 
      low buffering capacity, and moderately acidic pH. Healthy controls with CPITN 
      code 0 had normal resting flow rate, viscosity of saliva, quantity of stimulated 
      saliva, buffering capacity, and moderately acidic pH. CONCLUSION: Compared to 
      healthy controls, DS subjects showed decreased values for resting flow rate, pH, 
      quantity of stimulated saliva, and buffering capacity. A statistically 
      significant correlation was observed between the physical parameters of saliva 
      and periodontal condition in DS subjects (p < 0.05). CLINICAL SIGNIFICANCE: 
      Periodontal diseases start at a very early age and periodontal health 
      deteriorates at a faster rate in DS children for which saliva also plays its 
      part. Prime importance should be given to frequent oral hygiene and preventive 
      measures in DS children thus preventing accumulation of debris and plaque.
FAU - Chandra, Hurlihal Sharath
AU  - Chandra HS
AD  - Department of Paediatric and Preventive Dentistry, SJM Dental College and 
      Hospital, PB Road, Chitradurga, Karnataka, India, Phone: +91 9743048418, e-mail: 
      sharathchandrah2012@gmail.com.
FAU - Johnson, Jency Samuel
AU  - Johnson JS
AD  - Dubai Health Authority, HMS Mirdif Hospital, Dubai, UAE.
FAU - Sagar, Lakshmi
AU  - Sagar L
AD  - Department of Orthodontics, CKS Teja Institute of Dental Sciences & Research, 
      Chadalawada Nagar, Tirupati, Andhra Pradesh, India.
FAU - Naveen, Makam
AU  - Naveen M
AD  - Department of Orthodontics, SJM Dental College and Hospital, Chitradurga, 
      Karnataka, India.
FAU - Ziauddin, Shaik
AU  - Ziauddin S
AD  - Department of Orthodontics, Coorg Institute of Dental Sciences, Virajpet, 
      Karnataka, India.
FAU - Britto, Frankantony
AU  - Britto F
AD  - Department of Oral and Maxillofacial Pathology, SJM Dental College and Hospital, 
      Chitradurga, Karnataka, India.
FAU - Havaldar, Krishnamoorthy Shankar
AU  - Havaldar KS
AD  - Department of Pediatric and Preventive Dentistry, KVG Dental College and 
      Hospital, Sullia, Karnataka, India.
FAU - Shalini, Hurlihal
AU  - Shalini H
AD  - Department of Community Medicine, JJM Medical College, Davanagere, Karnataka, 
      India.
LA  - eng
PT  - Journal Article
DEP - 20230601
PL  - India
TA  - J Contemp Dent Pract
JT  - The journal of contemporary dental practice
JID - 101090552
SB  - IM
MH  - Humans
MH  - Child
MH  - Saliva
MH  - *Down Syndrome
MH  - Hydrogen-Ion Concentration
MH  - *Periodontal Diseases/complications
MH  - *Gingival Diseases
OTO - NOTNLM
OT  - Down syndrome
OT  - Periodontal disease Salivary factors.
EDAT- 2023/08/03 06:42
MHDA- 2023/08/04 06:43
CRDT- 2023/08/03 05:36
PHST- 2023/08/04 06:43 [medline]
PHST- 2023/08/03 06:42 [pubmed]
PHST- 2023/08/03 05:36 [entrez]
AID - 10.5005/jp-journals-10024-3481 [doi]
PST - epublish
SO  - J Contemp Dent Pract. 2023 Jun 1;24(6):372-380. doi: 
      10.5005/jp-journals-10024-3481.