PMID- 37537775
OWN - NLM
STAT- Publisher
LR  - 20230804
IS  - 2212-4020 (Electronic)
IS  - 1872-2105 (Linking)
DP  - 2023 Aug 3
TI  - Emerging Nanotechnology-based Therapeutics: A New Insight into Promising Drug 
      Delivery System for Lung Cancer Therapy.
LID - 10.2174/1872210517666230613154847 [doi]
AB  - BACKGROUND: Lung cancer is a foremost global health issue due to its poor 
      diagnosis. The advancement of novel drug delivery systems and medical devices 
      will aid its therapy. OBJECTIVE: In this review, the authors thoroughly introduce 
      the ideas and methods for improving nanomedicine- based approaches for lung 
      cancer therapy. This article provides mechanistic insight into various novel drug 
      delivery systems (DDSs) including nanoparticles, solid lipid nanoparticles, 
      liposomes, dendrimers, niosomes, and nanoemulsions for lung cancer therapy with 
      recent research work. This review provides insights into various patents 
      published for lung cancer therapy based on nanomedicine. This review also 
      highlights the current status of approved and clinically tested nanoformulations 
      for their treatment. METHODOLOGY: For finding scholarly related data for the 
      literature search, many search engines were employed including PubMed, Science 
      Direct, Google, Scihub, Google Scholar, Research Gate, Web of Sciences, and 
      several others. Various keywords and phrases were used for the search such as 
      "nanoparticles", "solid lipid nanoparticles", "liposomes", "dendrimers", 
      "niosomes", "nanoemulsions", "lung cancer", "nanomedicine", "nanomaterial", 
      "nanotechnology", "in vivo" and "in vitro". The most innovative and cutting-edge 
      nanotechnology-based approaches that are employed in pre-clinical and clinical 
      studies to address problems associated with lung cancer therapies are also 
      mentioned in future prospects. A variety of problems encountered with current 
      lung cancer therapy techniques that frequently led to inadequate therapeutic 
      success are also discussed in the end. CONCLUSION: The development of 
      nanoformulations at the pilot scale still faces some difficulties, but their 
      prospects for treating lung cancer appear to be promising in the future. Future 
      developments and trends are anticipated as the evaluation comes to a close.
CI  - Copyright(c) Bentham Science Publishers; For any queries, please email at 
      epub@benthamscience.net.
FAU - Verma, Ravinder
AU  - Verma R
AUID- ORCID: 0000-0003-3397-703X
AD  - Department of Pharmaceutical Sciences, Chaudhary Bansi Lal University, 
      Bhiwani-127021, India.
FAU - Rao, Lakshita
AU  - Rao L
AD  - Department of Pharmaceutical Sciences, Gurugram University, Gurugram, India.
FAU - Nagpal, Diksha
AU  - Nagpal D
AD  - Department of Pharmaceutical Sciences, Maharshi Dayanand University, 
      Rohtak-124001, India.
FAU - Yadav, Manish
AU  - Yadav M
AD  - Department of Pharmacy, G.D. Goenka University, Sohna Road, Gurugram-122103, 
      India.
FAU - Kumar, Vivek
AU  - Kumar V
AD  - Shri Ram College of Pharmacy, Karnal, India.
FAU - Kumar, Vikram
AU  - Kumar V
AD  - Shri Baba Mastnath Institute of Pharmaceutical Sciences and Research, Baba 
      Mastnath University, Rohtak - 124001, India.
FAU - Kumar, Harish
AU  - Kumar H
AD  - Department of Pharmaceutical Sciences, Chaudhary Bansi Lal University, 
      Bhiwani-127021, India.
FAU - Parashar, Jatin
AU  - Parashar J
AD  - B.S. Anangpuria Institute of Pharmacy, Faridabad-121004, India.
FAU - Bansal, Nitin
AU  - Bansal N
AD  - Department of Pharmaceutical Sciences, Chaudhary Bansi Lal University, 
      Bhiwani-127021, India.
FAU - Kumar, Manish
AU  - Kumar M
AD  - School of Pharmaceutical Sciences, CT University, Ludhiana- 142024 Punjab.
FAU - Pandey, Parijat
AU  - Pandey P
AD  - Department of Pharmaceutical Sciences, Gurugram University, Gurugram, India.
FAU - Mittal, Vineet
AU  - Mittal V
AD  - Department of Pharmaceutical Sciences, Maharshi Dayanand University, 
      Rohtak-124001, India.
FAU - Kaushik, Deepak
AU  - Kaushik D
AD  - Department of Pharmaceutical Sciences, Maharshi Dayanand University, 
      Rohtak-124001, India.
LA  - eng
PT  - Journal Article
DEP - 20230803
PL  - United Arab Emirates
TA  - Recent Pat Nanotechnol
JT  - Recent patents on nanotechnology
JID - 101291922
SB  - IM
OTO - NOTNLM
OT  - Nanomedicine
OT  - dendrimers
OT  - liposomes
OT  - lung cancer
OT  - nanoemulsions.
OT  - niosomes
OT  - solid lipid nanoparticles
EDAT- 2023/08/04 06:42
MHDA- 2023/08/04 06:42
CRDT- 2023/08/04 00:43
PHST- 2023/02/01 00:00 [received]
PHST- 2023/05/18 00:00 [revised]
PHST- 2023/05/23 00:00 [accepted]
PHST- 2023/08/04 06:42 [medline]
PHST- 2023/08/04 06:42 [pubmed]
PHST- 2023/08/04 00:43 [entrez]
AID - NANOTEC-EPUB-132504 [pii]
AID - 10.2174/1872210517666230613154847 [doi]
PST - aheadofprint
SO  - Recent Pat Nanotechnol. 2023 Aug 3. doi: 10.2174/1872210517666230613154847.