PMID- 3754056
OWN - NLM
STAT- MEDLINE
DCOM- 19860411
LR  - 20041117
IS  - 0033-8419 (Print)
IS  - 0033-8419 (Linking)
VI  - 159
IP  - 1
DP  - 1986 Apr
TI  - Prostatic cancer therapy: comparison of external-beam radiation and I-125 seed 
      implantation treatment of stages B and C neoplasms.
PG  - 249-52
AB  - Of 179 patients with stage B or C adenocarcinoma of the prostate, 106 underwent 
      iodine-125 seed-implant therapy (I-125 SI) and 73 received external-beam 
      radiation therapy (EB). A retrospective analysis determined disease-free survival 
      rate, local tumor control, and complication rate for each treatment group. The 
      5-year disease-free survival rates for SI-treated patients were 75% for stage B 
      and 30% for stage C groups. Corresponding rates for EB-treated patients were 75% 
      and 40%, respectively. The rate of local tumor control for stage B patients was 
      85% for SI-treated and 88% for EB-treated patients. The corresponding rates for 
      stage C tumors were 75% for SI-treated and 92% for EB-treated patients. The rate 
      of long-term complications in each group was approximately 10%. For stage B 
      cancer of the prostate, I-125 SI treatment is an acceptable alternative to EB 
      therapy; our data are inconclusive regarding stage C treatment, but EB therapy is 
      preferred.
FAU - Morton, J D
AU  - Morton JD
FAU - Harrison, L B
AU  - Harrison LB
FAU - Peschel, R E
AU  - Peschel RE
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Radiology
JT  - Radiology
JID - 0401260
RN  - 0 (Iodine Radioisotopes)
SB  - IM
MH  - Carcinoma/mortality/*radiotherapy
MH  - Humans
MH  - Iodine Radioisotopes/*therapeutic use
MH  - Male
MH  - Prostatic Neoplasms/mortality/*radiotherapy
EDAT- 1986/04/01 00:00
MHDA- 1986/04/01 00:01
CRDT- 1986/04/01 00:00
PHST- 1986/04/01 00:00 [pubmed]
PHST- 1986/04/01 00:01 [medline]
PHST- 1986/04/01 00:00 [entrez]
AID - 10.1148/radiology.159.1.3754056 [doi]
PST - ppublish
SO  - Radiology. 1986 Apr;159(1):249-52. doi: 10.1148/radiology.159.1.3754056.