PMID- 37562338
OWN - NLM
STAT- MEDLINE
DCOM- 20231102
LR  - 20231107
IS  - 1527-3288 (Electronic)
IS  - 0147-9563 (Linking)
VI  - 62
DP  - 2023 Nov-Dec
TI  - Predictors of gain in exercise capacity through cardiac rehabilitation: Sex and 
      age matter.
PG  - 200-206
LID - S0147-9563(23)00211-X [pii]
LID - 10.1016/j.hrtlng.2023.08.003 [doi]
AB  - BACKGROUND: Cardiac rehabilitation (CR) is a cornerstone of secondary prevention 
      that improves cardiovascular outcomes. However, the determinants of treatment 
      success are poorly understood. OBJECTIVES: We investigated the associations of 
      health-related quality of life (HRQoL), sex, age, employment status and housing 
      situation with improvement in exercise capacity throughout CR. METHODS: We 
      analyzed data from 392 CR outpatients (81% men and 19% women). Exercise capacity 
      at baseline and upon completion of the program was measured with the 6-minute 
      walk distance (6MWD). HRQoL at CR entry was assessed with the Short Form 36 
      Health Survey (SF-36). RESULTS: A multivariable regression analysis revealed that 
      both men and women showed significant improvement in exercise capacity (p < 
      .001). Female sex (B = 18.118, 95% CI 0.341 - 36.035, p = .046) and younger age 
      (B = -0.887, 95% CI -1.463 - -0.312, p = .003) emerged as predictors of greater 
      improvement, while HRQoL, employment status, and housing situation were not 
      associated with significant change in exercise capacity. The final model 
      explained 25% of the variance in exercise capacity change (adjusted R(2) = 0.25, 
      p < .001). CONCLUSIONS: Our results indicate that women and younger participants 
      benefit from CR by improving their exercise capacity. Employment status, housing 
      situation and HRQoL showed no effects on CR outcome.
CI  - Copyright (c) 2023 The Author(s). Published by Elsevier Inc. All rights reserved.
FAU - Fuentes Artiles, Ruben
AU  - Fuentes Artiles R
AD  - Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, 
      University Hospital Zurich, University of Zurich, Zurich, Switzerland; Department 
      of Medicine, Limmattal Hospital, Schlieren, Switzerland. Electronic address: 
      ruben.fuentes@bluewin.ch.
FAU - Euler, Sebastian
AU  - Euler S
AD  - Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, 
      University Hospital Zurich, University of Zurich, Zurich, Switzerland.
FAU - Auschra, Bianca
AU  - Auschra B
AD  - Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, 
      University Hospital Zurich, University of Zurich, Zurich, Switzerland.
FAU - da Silva, Hadassa Brito
AU  - da Silva HB
AD  - Department of Cardiology, University Heart Center, University Hospital Zurich, 
      University of Zurich, Zurich, Switzerland.
FAU - Niederseer, David
AU  - Niederseer D
AD  - Department of Cardiology, University Heart Center, University Hospital Zurich, 
      University of Zurich, Zurich, Switzerland.
FAU - Schmied, Christian
AU  - Schmied C
AD  - Department of Cardiology, University Heart Center, University Hospital Zurich, 
      University of Zurich, Zurich, Switzerland.
FAU - von Kanel, Roland
AU  - von Kanel R
AD  - Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, 
      University Hospital Zurich, University of Zurich, Zurich, Switzerland.
FAU - Jellestad, Lena
AU  - Jellestad L
AD  - Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, 
      University Hospital Zurich, University of Zurich, Zurich, Switzerland.
LA  - eng
PT  - Journal Article
DEP - 20230808
PL  - United States
TA  - Heart Lung
JT  - Heart & lung : the journal of critical care
JID - 0330057
SB  - IM
MH  - Male
MH  - Humans
MH  - Female
MH  - *Cardiac Rehabilitation/methods
MH  - Quality of Life
MH  - Exercise Tolerance
MH  - Walking
MH  - Heart
MH  - Exercise Therapy
OTO - NOTNLM
OT  - 6 min walk distance
OT  - Cardiac rehabilitation
OT  - Health-related quality of life
OT  - Sex
COIS- Declaration of Competing Interest The authors declare that they have no conflict 
      of interest.
EDAT- 2023/08/11 00:42
MHDA- 2023/08/11 00:43
CRDT- 2023/08/10 18:10
PHST- 2023/03/24 00:00 [received]
PHST- 2023/08/01 00:00 [revised]
PHST- 2023/08/03 00:00 [accepted]
PHST- 2023/08/11 00:43 [medline]
PHST- 2023/08/11 00:42 [pubmed]
PHST- 2023/08/10 18:10 [entrez]
AID - S0147-9563(23)00211-X [pii]
AID - 10.1016/j.hrtlng.2023.08.003 [doi]
PST - ppublish
SO  - Heart Lung. 2023 Nov-Dec;62:200-206. doi: 10.1016/j.hrtlng.2023.08.003. Epub 2023 
      Aug 8.