PMID- 37570300 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230814 IS - 2076-2615 (Print) IS - 2076-2615 (Electronic) IS - 2076-2615 (Linking) VI - 13 IP - 15 DP - 2023 Aug 2 TI - Maternal Supplementary Tapioca Polysaccharide Iron Improves the Growth Performance of Piglets by Regulating the Active Components of Colostrum and Cord Blood. LID - 10.3390/ani13152492 [doi] LID - 2492 AB - The purpose of this study was to investigate the effect of maternal supplementation with TpFe (tapioca polysaccharide iron) on reproductive performance, colostrum composition, cord blood active components of sows, and growth performance of their nursing piglets. Sixty healthy Duroc x Landrace x Yorkshire sows were randomly assigned to three groups at day 85 of gestation. The experimental diets included a basal diet supplemented with 100 mg/kg FeSO(4).H(2)O (CON group), the basal diet supplemented with 50 mg/kg TpFe (TpFe50 group), and the basal diet supplemented with 100 mg/kg TpFe (TpFe100 group), as calculated by Fe content. The experiment lasted from day 85 of gestation to the end of weaning (day 21 of lactation). Results showed that maternal supplementation with 100 mg/kg TpFe improved (p < 0.05) feed intake during lactation, live births, and birth weight of the litter (alive) and increased (p < 0.05) colostrum IgM (immunoglobulin m), IgA (immunoglobulin A), as well as the IgG levels, while it decreased (p < 0.05) the urea nitrogen and somatic cell count of sows. Moreover, sows in the TpFe100 group had higher (p < 0.05) serum iron levels and IgG. Additionally, maternal supplementation with 100 mg/kg TpFe increased (p < 0.05) iron level, total antioxidant capacity (T-AOC), glutathione peroxidase (GSH-px), catalase (CAT), IgG, red blood cells (RBC), and hemoglobin (Hb) of cord blood, similar with the iron content, T-AOC, GSH-px, IgG, RBC, Hb, hematocrit (HCT), and mean corpuscular volume (MCV) of weaned piglet blood. The diarrhea and mortality rates among the nursing piglets were decreased (p < 0.05), while the average weight at day 21 of age was increased (p < 0.05) in the TpFe100 group. Serum PRL (prolactin) levels of sows exhibited a positive correlation (p < 0.05) with live births. Suckling piglet diarrhea was positively correlated with colostrum urea nitrogen level but negatively correlated with colostrum IgM, IgG, and cord blood Hb content (p < 0.05). The mortality of suckling piglets was negatively correlated with serum iron content and IgM in colostrum, GSH-px, and IgG in cord serum of sows (p < 0.05). The average weight of weaning piglets was positively (p < 0.05) related to colostrum IgM and IgG levels, as well as cord serum RBC counts of sows on day 21. In conclusion, maternal supplementation with TpFe can improve the active components of colostrum and umbilical cord blood and improve the growth performance of suckling piglets. FAU - Deng, Shengting AU - Deng S AD - College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China. AD - Hunan Engineering Research Center of Intelligent Animal Husbandry, Changsha 410128, China. FAU - Fang, Chengkun AU - Fang C AD - College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China. AD - Hunan Engineering Research Center of Intelligent Animal Husbandry, Changsha 410128, China. FAU - Zhuo, Ruiwen AU - Zhuo R AD - College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China. AD - Hunan Engineering Research Center of Intelligent Animal Husbandry, Changsha 410128, China. FAU - Jiang, Qian AU - Jiang Q AUID- ORCID: 0000-0002-7840-0210 AD - College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China. AD - Hunan Engineering Research Center of Intelligent Animal Husbandry, Changsha 410128, China. FAU - Song, Yating AU - Song Y AD - College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China. AD - Hunan Engineering Research Center of Intelligent Animal Husbandry, Changsha 410128, China. FAU - Yang, Kaili AU - Yang K AD - College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China. AD - Hunan Engineering Research Center of Intelligent Animal Husbandry, Changsha 410128, China. FAU - Zhang, Sha AU - Zhang S AD - College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China. AD - Hunan Engineering Research Center of Intelligent Animal Husbandry, Changsha 410128, China. FAU - Hao, Juanyi AU - Hao J AD - College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China. AD - Hunan Engineering Research Center of Intelligent Animal Husbandry, Changsha 410128, China. FAU - Fang, Rejun AU - Fang R AD - College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China. AD - Hunan Engineering Research Center of Intelligent Animal Husbandry, Changsha 410128, China. LA - eng GR - 20211231GCZX/Hunan Engineering Research Center of Intelligent Animal Husbandry/ GR - 2021kjc-js060/Evaluation of the Effectiveness of Iron Polysaccharide Supplementation in Pig Diets/ PT - Journal Article DEP - 20230802 PL - Switzerland TA - Animals (Basel) JT - Animals : an open access journal from MDPI JID - 101635614 PMC - PMC10417719 OTO - NOTNLM OT - colostrum OT - cord blood OT - piglet OT - polysaccharide iron OT - sow COIS- The authors declare no real or perceived conflict of interest. There is no financial support from the company, and the product does not provide publicity benefits to the company. EDAT- 2023/08/12 10:50 MHDA- 2023/08/12 10:51 PMCR- 2023/08/02 CRDT- 2023/08/12 01:15 PHST- 2023/07/03 00:00 [received] PHST- 2023/07/25 00:00 [revised] PHST- 2023/07/31 00:00 [accepted] PHST- 2023/08/12 10:51 [medline] PHST- 2023/08/12 10:50 [pubmed] PHST- 2023/08/12 01:15 [entrez] PHST- 2023/08/02 00:00 [pmc-release] AID - ani13152492 [pii] AID - animals-13-02492 [pii] AID - 10.3390/ani13152492 [doi] PST - epublish SO - Animals (Basel). 2023 Aug 2;13(15):2492. doi: 10.3390/ani13152492.