PMID- 37573600 OWN - NLM STAT- MEDLINE DCOM- 20231204 LR - 20231217 IS - 1078-6791 (Print) IS - 1078-6791 (Linking) VI - 29 IP - 8 DP - 2023 Nov TI - The Effect of Warm Acupuncture on EOS, IgE, Inflammatory Factors, and T Lymphocyte Subsets in Patients with Allergic Rhinitis of Lung Qi Deficiency and Cold-Type. PG - 271-277 LID - AT8574 [pii] AB - OBJECTIVE: The purpose of this study was to investigate the effects of warming needle therapy on eosinophils, specific immunoglobulin E (IgE), inflammatory factors, and T lymphocyte subsets in patients with lung qi deficiency and cold-type allergic rhinitis (AR). METHODS: A total of 155 patients with lung qi deficiency and cold-type AR from May 2021 to December 2022 were randomly divided into a study group of 76 cases and a control group of 79 cases. The control group received medication (chlorpheniramine and fluticasone), and the study group received medication combined with warming needle therapy. The efficacy, TCM syndrome score, eosinophils, IgE, inflammatory factors (interleukin-6 (IL-6), IL-8, and tumor necrosis factor-alpha (TNF-alpha)), T lymphocyte subsets (CD3+, CD4+, and CD8+), and rhinoconjunctivitis quality of life questionnaire (RQLQ) scores were evaluated after 2 weeks of treatment. RESULTS: The total effective rate in the study group was 92.11%, which was higher than that in the control group (77.22%) (P < .05). The TCM syndrome scores of the study group were lower than those of the control group after 1 and 2 weeks of treatment (P < .05). The positive rate of eosinophils in the study group was lower than that in the control group after 1 week (47.37% vs. 64.56%, P < .05) and after 2 weeks (21.05% vs. 37.97%, P < .05) of treatment. The serum levels of specific IgE, IL-6, IL-8, and TNF-alpha in the study group were lower than those in the control group after 1 and 2 weeks of treatment (P < .05). The peripheral blood levels of CD3+ and CD4+ were higher and the peripheral blood level of CD8+ was lower in the study group than in the control group after 1 and 2 weeks of treatment (P < .05). The RQLQ scores of the study group were lower than those of the control group after 1 and 2 weeks of treatment (P < .05). CONCLUSION: Warming needle therapy can effectively improve the clinical symptoms of patients with lung qi deficiency and cold-type AR, reduce inflammation, and enhance immune function. FAU - Sun, Dunpo AU - Sun D FAU - Jiang, Mingxiao AU - Jiang M FAU - Lu, Meng AU - Lu M FAU - Ma, Xiaomin AU - Ma X FAU - Shang, Guochao AU - Shang G FAU - Wang, Yisong AU - Wang Y LA - eng PT - Journal Article PT - Randomized Controlled Trial PL - United States TA - Altern Ther Health Med JT - Alternative therapies in health and medicine JID - 9502013 RN - 0 (Tumor Necrosis Factor-alpha) RN - 0 (Interleukin-6) RN - 0 (Interleukin-8) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Humans MH - Qi MH - Quality of Life MH - Tumor Necrosis Factor-alpha MH - Interleukin-6 MH - Interleukin-8 MH - *Rhinitis, Allergic/therapy MH - *Acupuncture Therapy MH - Syndrome MH - Immunoglobulin E MH - Lung MH - T-Lymphocyte Subsets EDAT- 2023/08/13 18:41 MHDA- 2023/12/04 12:43 CRDT- 2023/08/13 16:52 PHST- 2023/12/04 12:43 [medline] PHST- 2023/08/13 18:41 [pubmed] PHST- 2023/08/13 16:52 [entrez] AID - AT8574 [pii] PST - ppublish SO - Altern Ther Health Med. 2023 Nov;29(8):271-277.